<p>Difference in Pain and Discomfort of Comparable Wrist Movements Induced by Magnetic or Electrical Stimulation for Peripheral Nerves in the Dorsal Forearm</p>

Medical Devices Evidence and Research, Год журнала: 2020, Номер Volume 13, С. 439 - 447

Опубликована: Дек. 1, 2020

Both repetitive peripheral magnetic stimulation (rPMS) and transcutaneous electrical current (TES) could elicit the limb movements; it is still unclear how subjective sensation changed according to amount of movements. We investigated pain discomfort induced by newly developed rPMS TES nerves in dorsal forearm.The subjects were 12 healthy adults. The stimulus site was right forearm; thus, when stimulated, wrist dorsiflexion induced. delivered new stimulator, Pathleader at 10 intensity levels, 1-mA increments. duration each 2 s. analysis parameters discomfort, measured a numerical rating scale. scale corresponding levels integrated range movement (iROM) or compared. values analyzed two-way repeated measures ANOVA with conditions (rPMS, TES) seven iROM (20-140 ºs).In experiments, stimuli administered all intensities. In none dropped out between 1 16 mA, but there dropouts intensities as follows: subject 17 20 22 23 27 29 mA 21 24 26 mA. main effects significant for discomfort. Post hoc demonstrated that significantly lower compared above 60 ºs 80 ºs, respectively.New Pathleader, caused less than TES, this only evident comparatively large joint movements occurred.

Язык: Английский

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Modulation of the Corticomotor Excitability by Repetitive Peripheral Magnetic Stimulation on the Median Nerve in Healthy Subjects

Frontiers in Neural Circuits, Год журнала: 2021, Номер 15

Опубликована: Март 18, 2021

Objective: We aimed to examine the effects of repetitive peripheral nerve magnetic stimulation (rPNMS) on excitability contralateral motor cortex and function upper limb in healthy subjects. Methods: Forty-six subjects were randomly assigned either a group ( n = 23) or sham 23). The received using pulses at 20 Hz, which applied median non-dominant hand, whereas underwent same protocol without output. primary outcome was transcranial (TMS)-induced corticomotor for abductor pollicis brevis stimulated hand terms resting threshold (rMT), slope recruitment curve, peak amplitude evoked potential (MEP), measured baseline immediately after each session. secondary outcomes including dexterity grip strength assessed baseline, stimulation, 24 h post-stimulation. Results: Compared with increased intervention. also curve intervention enhanced h. However, between-group difference changes not significant. significant associated their value. Conclusions: Repetitive may modulate together possible lasting improvement dexterity, indicating that it might be helpful clinical rehabilitation.

Язык: Английский

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Effect of High-Frequency Repetitive Peripheral Magnetic Stimulation on Motor Performance in Intracerebral Haemorrhage: A Clinical Trial

Journal of Stroke and Cerebrovascular Diseases, Год журнала: 2022, Номер 31(7), С. 106446 - 106446

Опубликована: Май 2, 2022

Язык: Английский

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A new method to elicit and measure movement illusions in stroke by means of muscle tendon vibration: the Standardized Kinesthetic Illusion Procedure (SKIP)

Somatosensory & Motor Research, Год журнала: 2020, Номер 37(1), С. 28 - 36

Опубликована: Янв. 2, 2020

Purpose: Muscle tendon vibration (MTV) strongly activates muscle spindles and can evoke kinaesthetic illusions. Although potentially relevant for sensorimotor rehabilitation in stroke, MTV is scarcely used clinical practice, likely because of the absence standardised procedures to elicit characterise movement This work developed validated a Standardised Kinaesthetic Illusion Procedure (SKIP) favour use MTV-induced illusions settings.Materials methods: SKIP scores were obtained 15 individuals with chronic stroke 18 age- gender-matched healthy counterparts. A further 13 subjects tested provide more data general population. was applied over Achilles scoring system characterised clearness direction ankle dorsiflexion movements.Results: All participants perceived on paretic side significantly lower compared non healthy. Illusions less clear sometimes unexpected directions impaired ankle, but still possible presence deficits.Conclusions: represents an ancillary useful method movements induced by MTV. could be assess processing proprioceptive afferents their potential impact motor control recovery. It may guide therapy improve Future needed investigate metrological properties our (reliability, responsiveness, etc.), also neurophysiological underpinnings

Язык: Английский

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Repetitive peripheral sensory stimulation for motor recovery after stroke: a scoping review

Topics in Stroke Rehabilitation, Год журнала: 2024, Номер 31(7), С. 723 - 737

Опубликована: Март 7, 2024

Enhancing afferent information from the paretic limb can improve post-stroke motor recovery. However, uncertainties exist regarding varied sensory peripheral neuromodulation protocols and their specific impacts. This study outlines use of repetitive stimulation (RPSS) magnetic (rPMS) in individuals with stroke.

Язык: Английский

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Magnetic nanomaterials mediate precise magnetic therapy

Biomedical Physics & Engineering Express, Год журнала: 2024, Номер 10(5), С. 052001 - 052001

Опубликована: Июль 9, 2024

Abstract Magnetic nanoparticle (MNP)-mediated precision magnet therapy plays a crucial role in treating various diseases. This therapeutic strategy compensates for the limitations of low spatial resolution and focusing magnetic stimulation, realizes goal wireless teletherapy with precise targeting focal areas. paper summarizes preparation methods nanomaterials, properties nanoparticles, biological effects, measurement detecting magnetism; discusses research progress magnetotherapy treatment psychiatric disorders, neurological injuries, metabolic bone-related looks forward to future development trend therapy.

Язык: Английский

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Variation of corticospinal excitability during kinesthetic illusion induced by musculotendinous vibration

Journal of Neurophysiology, Год журнала: 2023, Номер 130(5), С. 1118 - 1125

Опубликована: Сен. 14, 2023

Despite being studied for more than 50 years, the neurophysiological mechanisms underlying vibration (VIB)-induced kinesthetic illusions are still unclear. The aim of this study was to investigate how corticospinal excitability tested by transcranial magnetic stimulation (TMS) is modulated during VIB-induced illusions. Twenty healthy adults received over wrist flexor muscles (80 Hz, 1 mm, 10 s). TMS applied primary motor cortex representation extensors at 120% resting threshold in four random conditions (10 trials/condition): baseline (without VIB), s, 5 and s after VIB onset. Means motor-evoked potential (MEP) amplitudes latencies were calculated. Statistical analysis found a significant effect (stimulation timings) on MEP (P = 0.035). Paired-comparisons demonstrated lower compared with 0.025) 0.003), although none them differed from values. Results suggest time-specific modulation antagonistic those vibrated, i.e., involved perceived movement. An early decrease observed followed stabilization values near subsequent time points. At illusion not yet or strong enough upregulate networks coherent proprioceptive input. Spinal mechanisms, such as reciprocal inhibition, could also contribute drive nonvibrated short period before emerges. Our results that neuromodulatory effects likely time-dependent, future work needed further mechanisms.NEW & NOTEWORTHY when perceiving evolves dynamically time. This might be linked delayed occurrence progressive increase strength illusory perception first seconds start. Different spinal/cortical play VIB, depending muscle, presence/absence an illusion, specific timing which pre/post VIB.

Язык: Английский

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Visual feedback improves movement illusions induced by tendon vibration after chronic stroke

Journal of NeuroEngineering and Rehabilitation, Год журнала: 2021, Номер 18(1)

Опубликована: Окт. 30, 2021

Illusion of movement induced by tendon vibration is commonly used in rehabilitation and seems valuable for motor after stroke, playing a role cerebral plasticity. The aim was to study if congruent visual cues using Virtual Reality (VR) could enhance the illusion wrist among participants with stroke.We included 20 chronic stroke participants. They experienced their (100 Hz, 30 times) inducing movement. Three VR conditions were added vibration: moving virtual hand (Moving condition); static (Static or no at all (Hidden condition). evaluated each condition intensity illusory Likert scale, sensation wrist's degree scale they answered questionnaire about preferred condition.The Moving significantly superior Hidden Static terms (p < 0.001) extension 0.001). There significant difference between these 2 criteria. considered best one increase (in 70% participants). Two did not feel any movement.This showed interest order consistency regardless clinical severity. By stimulating brain areas, this visuo-proprioceptive feedback be an interesting tool rehabilitation. Record number Clinical Trials: NCT04130711, registered on October 17th 2019 ( https://clinicaltrials.gov/ct2/show/NCT04130711?id=NCT04130711&draw=2&rank=1 ).

Язык: Английский

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Theta-Burst Stimulation of Forearm Muscles in Patients With Complex Regional Pain Syndrome: Influence on Brain and Clinical Outcomes

Frontiers in Pain Research, Год журнала: 2021, Номер 2

Опубликована: Сен. 21, 2021

Objective: Complex regional pain syndrome (CRPS) is a common condition characterized by the changes in brain that are not yet addressed conventional treatment regimens. Repetitive peripheral magnetic stimulation (rPMS) of muscles painless and non-invasive can influence these (the induction plasticity) to reduce improve motricity. In patients with CRPS, this open-label pilot study tested rPMS after-effects on intensity sensorimotor control upper limb along excitability primary motor cortex (M1). Methods: Eight CRPS were enrolled single-session program. Patients at pre- post-rPMS over flexor digitorum superficialis (FDS) muscle. The clinical outcomes intensity, proprioception, active range motion (ROM), grip strength. M1 was using single- paired-pulse transcranial (TMS) M1. Results: our small sample study, reduced instant week pain, improved proprioception ROM, hemispheric imbalance several TMS outcomes. more contralateral side hyperactivated baseline, reduced. Discussion: This provided promising findings for use focus plastic changes. Future randomized, placebo-controlled trials should confirm existence causal relationship between decrease pain. will favor development personalized treatments neurostimulation CRPS.

Язык: Английский

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Effects of Repetitive Peripheral Magnetic Stimulation through Hand Splint Materials on Induced Movement and Corticospinal Excitability in Healthy Participants

Brain Sciences, Год журнала: 2022, Номер 12(2), С. 280 - 280

Опубликована: Фев. 17, 2022

Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive neuromodulation technique. Magnetic fields induced by rPMS pass through almost all materials, and it has clinical applications for neurorehabilitation. However, the effects of clothing orthosis on movement corticospinal excitability remain unclear. The aim this study was to determine whether induces enhances hand splint materials. applied directly skin (L0) one (L1) or two (L2) layers material in 14 healthy participants at 25-Hz, 2-s train per 6 s total 20 min. delivered forearm with stimulus intensity set 1.5-times intensity-induced muscle contractions under L0 condition. We recorded wrist movements during motor-evoked potentials extensor carpi radialis pre- post-application. results showed that L1, facilitated but not L1 L2. This suggests can make electromagnetic induction periphery even when over demonstrates potential technique

Язык: Английский

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