Neurorehabilitation and neural repair,
Год журнала:
2016,
Номер
30(10), С. 963 - 971
Опубликована: Май 25, 2016
Background.
Gait
is
influenced
by
higher
order
cognitive
and
cortical
control
mechanisms.
Functional
near
infrared
spectroscopy
(fNIRS)
has
been
used
to
examine
frontal
activation
during
walking
in
healthy
older
adults,
reporting
increased
oxygenated
hemoglobin
(HbO2)
levels
dual
task
(DT),
compared
with
usual
walking.
Objective.
To
investigate
the
role
of
lobe
DT
obstacle
negotiation,
adults
patients
Parkinson’s
disease
(PD).
Methods.
Thirty-eight
(mean
age
70.4
±
0.9
years)
68
PD
71.7
1.1
years,)
performed
3
tasks:
(
a)
walking,
b)
c)
obstacles
fNIRS
accelerometers.
Linear-mix
models
were
detect
changes
between
groups
within
tasks.
Results.
Patients
had
P
<
.030).
During
DT,
HbO2
only
.001).
=
.001)
tended
increase
.053).
Higher
cost
.003)
worse
performance
observed
Conclusions.
A
different
pattern
was
groups.
The
suggests
that
prefrontal
cortex
plays
an
important
already
simple
However,
relative
baseline
negotiation
not
demonstrates
depends
on
nature
task.
These
findings
may
have
implications
for
rehabilitation
gait
PD.
Lab on a Chip,
Год журнала:
2017,
Номер
18(2), С. 217 - 248
Опубликована: Ноя. 28, 2017
Wearable
sensors
have
recently
seen
a
large
increase
in
both
research
and
commercialization.
However,
success
wearable
has
been
mix
of
progress
setbacks.
Most
commercial
smart
adaptation
existing
mechanical,
electrical
optical
methods
measuring
the
body.
This
involved
innovations
how
to
miniaturize
sensing
technologies,
make
them
conformal
flexible,
development
companion
software
that
increases
value
measured
data.
chemical
modalities
experienced
greater
challenges
adoption,
especially
for
non-invasive
sensors.
There
also
significant
making
fundamental
improvements
electrical,
modalities,
improving
their
specificity
detection.
Many
these
can
be
understood
by
appreciating
body's
surface
(skin)
as
more
an
information
barrier
than
source.
With
deeper
understanding
faced
state-of-the-art
sensor
technology,
roadmap
becomes
clearer
creating
next
generation
breakthroughs.
Advanced Materials,
Год журнала:
2019,
Номер
32(15)
Опубликована: Июль 8, 2019
Abstract
Recent
advances
in
soft
materials
and
system
integration
technologies
have
provided
a
unique
opportunity
to
design
various
types
of
wearable
flexible
hybrid
electronics
(WFHE)
for
advanced
human
healthcare
human–machine
interfaces.
The
biocompatible
with
miniaturized
wireless
systems
is
undoubtedly
an
attractive
prospect
the
sense
that
successful
device
performance
requires
high
degrees
mechanical
flexibility,
sensing
capability,
user‐friendly
simplicity.
Here,
most
up‐to‐date
materials,
sensors,
system‐packaging
develop
WFHE
are
provided.
Details
mechanical,
electrical,
physicochemical,
properties
discussed
integrated
sensor
applications
healthcare,
energy,
environment.
In
addition,
limitations
current
discussed,
as
well
key
challenges
future
direction
WFHE.
Collectively,
all‐inclusive
review
newly
developed
along
summary
imperative
requirements
material
properties,
capabilities,
performance,
skin
integrations
Annals of the New York Academy of Sciences,
Год журнала:
2018,
Номер
1464(1), С. 5 - 29
Опубликована: Авг. 7, 2018
Abstract
The
past
few
decades
have
seen
a
rapid
increase
in
the
use
of
functional
near‐infrared
spectroscopy
(fNIRS)
cognitive
neuroscience.
This
fast
growth
is
due
to
several
advances
that
fNIRS
offers
over
other
neuroimaging
modalities
such
as
magnetic
resonance
imaging
and
electroencephalography/magnetoencephalography.
In
particular,
harmless,
tolerant
bodily
movements,
highly
portable,
being
suitable
for
all
possible
participant
populations,
from
newborns
elderly
experimental
settings,
both
inside
outside
laboratory.
this
review
we
aim
provide
comprehensive
state‐of‐the‐art
basics,
technical
developments,
applications.
discuss
some
open
challenges
potential
neuroscience
research,
with
particular
focus
on
naturalistic
environments
social
NeuroImage,
Год журнала:
2013,
Номер
85, С. 28 - 50
Опубликована: Июнь 5, 2013
This
review
is
aimed
at
presenting
the
state-of-the-art
of
time
domain
(TD)
functional
near-infrared
spectroscopy
(fNIRS).
We
first
introduce
physical
principles,
basics
modeling
and
data
analysis.
Basic
instrumentation
components
(light
sources,
detection
techniques,
delivery
collection
systems)
a
TD
fNIRS
system
are
described.
A
survey
past,
existing
next
generation
systems
used
for
research
clinical
studies
presented.
Performance
assessment
standardization
issues
also
discussed.
Main
strengths
weakness
highlighted,
in
comparison
with
continuous
wave
(CW)
fNIRS.
Issues
like
quantification
hemodynamic
response,
penetration
depth,
depth
selectivity,
spatial
resolution
contrast-to-noise
ratio
critically
examined,
help
experimental
results
performed
on
phantoms
or
vivo.
Finally
we
give
an
account
technological
developments
that
would
pave
way
broader
use
neuroimaging
community.
NeuroImage Clinical,
Год журнала:
2015,
Номер
8, С. 1 - 31
Опубликована: Янв. 1, 2015
Functional,
molecular
and
genetic
neuroimaging
has
highlighted
the
existence
of
brain
anomalies
neural
vulnerability
factors
related
to
obesity
eating
disorders
such
as
binge
or
anorexia
nervosa.
In
particular,
decreased
basal
metabolism
in
prefrontal
cortex
striatum
well
dopaminergic
alterations
have
been
described
obese
subjects,
parallel
with
increased
activation
reward
areas
response
palatable
food
cues.
Elevated
region
responsivity
may
trigger
craving
predict
future
weight
gain.
This
opens
way
prevention
studies
using
functional
perform
early
diagnostics
phenotype
subjects
at
risk
by
exploring
different
neurobehavioral
dimensions
choices
motivation
processes.
first
part
this
review,
advantages
limitations
techniques,
magnetic
resonance
imaging
(fMRI),
positron
emission
tomography
(PET),
single
photon
computed
(SPECT),
pharmacogenetic
fMRI
near-infrared
spectroscopy
(fNIRS)
will
be
discussed
context
recent
work
dealing
behavior,
a
particular
focus
on
obesity.
second
non-invasive
strategies
modulate
food-related
processes
functions
presented.
At
leading
edge
brain-based
technologies
is
real-time
(rtfMRI)
neurofeedback,
which
powerful
tool
better
understand
complexity
human
brain–behavior
relationships.
rtfMRI,
alone
when
combined
other
techniques
tools
EEG
cognitive
therapy,
could
used
alter
plasticity
learned
behavior
optimize
and/or
restore
healthy
cognition
behavior.
Other
promising
neuromodulation
approaches
being
explored
are
repetitive
transcranial
stimulation
(rTMS)
direct-current
(tDCS).
Converging
evidence
points
value
these
study
basic
mechanisms
underlying
treat
its
disorders.
Both
compared
light
field,
while
addressing
technical
practical
questions.
The
third
review
dedicated
invasive
strategies,
vagus
nerve
(VNS)
deep
(DBS).
combination
approaches,
experimental
unravel
intricate
relationships
between
homeostatic
hedonic
circuits.
Their
potential
additional
therapeutic
combat
pharmacorefractory
morbid
acute
discussed,
terms
challenges,
applicability
ethics.
general
discussion,
we
put
core
fundamental
research,
therapy
First,
discuss
possibility
identify
new
biological
markers
functions.
Second,
highlight
individualized
medicine.
Third,
introduce
ethical
questions
that
concomitant
emergence
therapies.
Journal of Cerebral Blood Flow & Metabolism,
Год журнала:
2015,
Номер
36(4), С. 647 - 664
Опубликована: Ноя. 24, 2015
Neurovascular
coupling
reflects
the
close
temporal
and
regional
linkage
between
neural
activity
cerebral
blood
flow.
Although
providing
mechanistic
insight,
our
understanding
of
neurovascular
is
largely
limited
to
non-physiological
ex
vivo
preparations
non-human
models
using
sedatives/anesthetics
with
confounding
cerebrovascular
implications.
Herein,
particular
focus
on
humans,
we
review
present
highlight
current
approaches
assess
these
responses
application
in
health
disease.
Moreover,
new
guidelines
for
standardizing
assessment
humans.
To
improve
reliability
measurement
related
interpretation,
utility
automated
software
demonstrated,
which
provides
capacity
coalescing
repetitive
trials
time
intervals
into
single
contours
extracting
numerous
metrics
(e.g.,
conductance
pulsatility,
critical
closing
pressure,
etc.)
according
patterns
interest
peak/minimum
response,
etc.).
This
versatile
also
permits
normalization
dynamic
changes
arterial
gases,
potentially
influencing
hyperemic
response.
It
hoped
that
guidelines,
combined
newly
developed
openly
available
software,
will
help
propel
humans
lead
improved
clinical
management
this
physiological
function.
