Опубликована: Ноя. 16, 2023
The literature regarding the neural basis of syntax is a varied landscape mutually incompatible descriptions how and where hierarchical structure generated processed. In this work, I first lay out predominant neurobiological models syntax, followed by tour evidence for against brain regions argued to be implicated in process. close discussing compatibility theoretical with empirical data.
Язык: Английский
Brain and Language, Год журнала: 2025, Номер 264, С. 105549 - 105549
Опубликована: Фев. 20, 2025
Although there is a sizeable body of literature on sentence comprehension and processing both in healthy disordered language users, the production remains much more sparse. Linguistic computational descriptions expressive syntactic deficits aphasia are especially rare. In addition, neuroimaging (psycho) linguistic literatures operate largely separately. this paper, I will first lay out theoretical land with regard to psycholinguistic models production. then provide brief narrative overview large-scale meta-analysis as it pertains computation, followed by an attempt integrate findings from functional clinical neuroimaging. Finally, surrounding propose path forward close some existing gaps.
Язык: Английский
Процитировано
0
Brain Communications, Год журнала: 2025, Номер 7(2)
Опубликована: Янв. 1, 2025
Abstract Functional neuroimaging studies in neurotypical subjects correlate sentence comprehension to a left fronto-temporo-parietal network. Recent voxel-based lesion-symptom mapping (VLSM) of aphasia confirm the link between and posterior region including angular gyrus, supra-marginal gyrus postero-superior division temporal lobe but support pre-frontal involvement inconsistently. However, these focus on thematic role assignment without considering morphosyntactic processes. Hence, available VLSM evidence could provide partial view neurofunctional substrate comprehension. In present study, both processes were evaluated systematically same types each participant, more detailed picture Participants (33 patients with post-stroke 90 healthy controls) completed sentence–picture matching task which active passive, declarative reversible sentences paired morphosyntactic, lexical-semantic alternatives. Phonological short-term memory tasks also administered. Aphasic participants selected from an initial pool 70 because they scored below norm foils (n = 18) or morphological 15), within foils. The correlates starkly distinguishable. Pre-frontal areas inferior middle frontal involved directly processing local features only indirectly When damaged, errors always co-occurred errors, probably damage disrupts grammatical roles ultimately that roles. Morphosyntactic not influenced by word order canonicity. contrast, selective reversals linked parietal significantly order, occurring passive than sentences. An area was critical for non-canonical order. comprehension, regions are (at least simple sentences). Temporal Postero-superior retrieving verb argument structure. Parietal assigning morphosyntactically analysed constituents appropriate role, thus serving crucial function re-analysis. Each plays prevailing exclusive processes, interacting other network possibly providing language-specific domain-general resources needed at various stages
Язык: Английский
Процитировано
0
European Child & Adolescent Psychiatry, Год журнала: 2025, Номер unknown
Опубликована: Апрель 3, 2025
Язык: Английский
Процитировано
0
Brain Research Bulletin, Год журнала: 2025, Номер unknown, С. 111334 - 111334
Опубликована: Апрель 1, 2025
The coexistence of speech disorders in stroke patients can negatively impact their quality life and rehabilitation outcomes. Scalp acupuncture (SA) has shown potential as a non-pharmacological treatment for post-stroke aphasia (PSA). As the location SA PSA is controversial, this study aims to utilize neuroimaging techniques identifying validation promising target. was divided into two phases. In phase Ⅰ, three pipelines, including lesion mapping, meta-analysis, resting-state functional connectivity, were integrated targets. Ⅱ, Centro-square needling manipulations then applied evaluate prescription with PSA. left middle temporal gyrus (MTG) chosen one targets it had highest occurrence among outcomes pipelines. It been discovered that technique MTG immediately enhance reduced connectivity (FC) between frontal caused by diseases. Moreover, enhances FC superior gyrus, which may constitute therapeutic mechanism underlying its efficacy improving verb understanding scores on Chinese Rehabilitation Research Center Standard Aphasia Examination scale. summary, protocol integrating traditional medicine help refine locations
Язык: Английский
Процитировано
0
Frontiers in Language Sciences, Год журнала: 2023, Номер 2
Опубликована: Авг. 9, 2023
OPINION article Front. Lang. Sci., 09 August 2023Sec. Neurobiology of Language Volume 2 - 2023 | https://doi.org/10.3389/flang.2023.1217837
Язык: Английский
Процитировано
6
Cerebral Cortex, Год журнала: 2024, Номер unknown
Опубликована: Янв. 23, 2024
Abstract Numerous studies have been devoted to neural mechanisms of a variety linguistic tasks (e.g. speech comprehension and production). To date, however, whether how the patterns underlying different are similar or differ remains elusive. In this study, we compared 3 mainly concerning production. address this, multivariate regression approaches with lesion/disconnection symptom mapping were applied data from 216 stroke patients damage left hemisphere. The results showed that could predict both poststroke scores production tasks; these exhibited shared regions on temporal pole hemisphere as well unique contributing prediction for each domain. Lower in associated lesions/abnormalities superior gyrus middle gyrus, while lower inferior parietal lobe frontal lobe. These suggested an important role ventral dorsal stream pathways (i.e. supporting dual model) highlighted applicability novel disconnectome-based cognitive neuroscience research.
Язык: Английский
Процитировано
2
Brain, Год журнала: 2024, Номер unknown
Опубликована: Июнь 18, 2024
Abstract There is a rich tradition of research on the neuroanatomical correlates spoken language production in aphasia using constrained tasks (e.g., picture naming), which offer controlled insights into distinct processes that govern speech and (i.e., lexical-semantic access, morphosyntactic construction, phonological encoding, motor programming/execution). Yet these do not necessarily reflect everyday use. In contrast, naturalistic (also referred to as connected or discourse) more closely approximates typical processing demands, requiring dynamic integration all aspects language. The brain bases remain relatively unknown, however, part because difficulty deriving features are salient, quantifiable, interpretable relative both speech-language extant literature. present cross-sectional observational study seeks address challenges by leveraging validated comprehensive auditory-perceptual measurement system yields four explanatory dimensions performance—Paraphasia (misselection words sounds), Logopenia (paucity words), Agrammatism (grammatical omissions), Motor (impaired We used this characterize large representative sample individuals with acute post-stroke (n = 118). Scores each were correlated lesion metrics, multivariate associations among regions then explored. Our findings revealed yet overlapping throughout left-hemisphere network. Paraphasia associated primarily posterior regions, spanning dorsal ventral streams, critical for access encoding. anterior stream involved construction planning/execution respectively. Collectively, we view results constituting brain-behavior model aphasia, aligning historical contemporary accounts neurobiology production.
Язык: Английский
Процитировано
2
Cortex, Год журнала: 2024, Номер 179, С. 77 - 90
Опубликована: Авг. 3, 2024
Язык: Английский
Процитировано
2
Brain Communications, Год журнала: 2024, Номер 6(6)
Опубликована: Янв. 1, 2024
Abstract Understanding and interpreting how words are organized in a sentence to convey distinct meanings is cornerstone of human communication. The neural underpinnings this ability, known as syntactic comprehension, far from agreed upon current neurocognitive models language comprehension. Traditionally, left frontal regions (e.g. posterior inferior gyrus) were considered critical, while more recently, temporal (most prominently, middle have been identified indispensable Syntactic processing has investigated by using different types non-canonical sentences i.e. those that do not follow prototypical word order syntactically complex. However, can be complex for linguistic reasons, thus, their comprehension might rely on underpinnings. In cross-sectional study, we explored the correlates investigating roles hemisphere brain white matter pathways with levels complexity. Participants assessed at single point time structural MRI behavioural tests. Employing lesion–symptom mapping indirect disconnection cohort 131 stroke survivors, our analysis revealed following underlying crucial general comprehension: mid-posterior superior gyrus, gyrus sulcus longitudinal fasciculus, fronto-occipital uncinate fasciculus tracts crossing most part corpus callosum. We further found significant involvement connecting lobes types. Spared connections between critical requiring long-distance retrieval (spared both subject object extraction spared arcuate extraction) but passive canonical declarative sentences. Our results challenge traditional emphasize primary role regions, such Broca’s area, basic structure findings suggest gradient complexity, rather than clear-cut dichotomy structures. contribute nuanced understanding architecture highlight potential directions future research.
Язык: Английский
Процитировано
2
Journal of Cognitive Neuroscience, Год журнала: 2023, Номер 35(12), С. 2067 - 2088
Опубликована: Янв. 1, 2023
Abstract The capacity for language is a defining property of our species, yet despite decades research, evidence on its neural basis still mixed and generalized consensus difficult to achieve. We suggest that this partly caused by researchers “language” in different ways, with focus wide range phenomena, properties, levels investigation. Accordingly, there very little agreement among cognitive neuroscientists the operationalization fundamental concepts be investigated neuroscientific experiments. Here, we review chains derivation neuroscience language, focusing how hypothesis under consideration defined combination theoretical methodological assumptions. first attempt disentangle complex relationship between linguistics, psychology, field. Next, conclusions can drawn from any experiment are inherently constrained auxiliary assumptions, both methodological, which validity rests. These issues discussed context classical experimental manipulations as well study designs employ novel approaches such naturalistic stimuli computational modeling. conclude proposing highly interdisciplinary field requires form explicit statements concerning definitions, choices, other constraining factors involved their work.
Язык: Английский
Процитировано
5