Countermeasure for interfered monitoring ion of perfluorooctanesulfonic acid (PFOS) from intrinsic food samples based on LC-MS/MS analysis of per- and polyfluoroalkyl substances

Journal of Food Composition and Analysis, Год журнала: 2024, Номер 133, С. 106436 - 106436

Опубликована: Июнь 20, 2024

This study aimed to investigate the risk of false liquid chromatography with tandem mass spectrometry (LC-MS/MS) detection (electrospray ionization-positive mode, m/z 499 > 80) perfluorooctanesulfonic acid (PFOS) caused by interference peak from food matrices for analysis per- and polyfluoroalkyl substances (PFAS). A complete separation between PFOS peaks was achieved using conventional analytical conditions mobile phase based on C18 column 5 mmoL L-1 ammonium acetate containing water/acetonitrile. Moreover, chemical is identified taurochenodeoxycholic egg sample. Then, a variety approaches have been used quantify PFAS C4-C9 perfluoro chain type solid extraction mixed standard (PFAC-MXC). The amounts in certified fish paste were determined within uncertainty level (95% confidence interval). Among four types foods (meat, vegetable, fish, egg), these well recovered (within around 80%–120%) good reproducibility (RSD (%) < 15%). Our approach suitable quantifying chains matrices.

Язык: Английский

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Revealing Hidden Risks: In Vitro Analysis of PFAS Hazards in Mytilus galloprovincialis Gills and Digestive Gland

Journal of Hazardous Materials, Год журнала: 2024, Номер 485, С. 136823 - 136823

Опубликована: Дек. 9, 2024

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals known for their persistence bioaccumulation, leading to widespread environmental contamination. Despite recognised risks, particularly aquatic wildlife, including marine invertebrates, detailed impact studies limited. PFAS can be categorised according the length of compound chain, with short-chain announced as a safer alternative more commonly used long-chain PFAS. However, recent evidence suggests that also pose significant risks. The present study evaluated adverse effects six compounds-two (PFHxA, 6:2 FTA) four (PFUnDA, PFDoA, PFTriDA, PFTeDA)- on digestive gland gills mussels, Mytilus galloprovincialis, using in vitro assays. results showed organ-specific responses: was sensitive PFHxA, increased catalase activity decreased total antioxidant capacity, cellular damage observed only at higher concentrations PFTriDA. Gills were affected by PFDoA PFTeDA, inhibited enzyme oxidative stress. PFHxA PFTriDA inhibition acetylcholinesterase activity. FTA had lowest both organs, while most harmful. These findings underscore need thorough risk assessments PFAS, considering chain effects.

Язык: Английский

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Distribution characteristics and transformation mechanism of per- and polyfluoroalkyl substances in drinking water sources: A review

The Science of The Total Environment, Год журнала: 2023, Номер 916, С. 169566 - 169566

Опубликована: Дек. 29, 2023

Язык: Английский

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Superparamagnetic nanofluid based on target-specific deep eutectic solvent for determination of multiple perfluoroalkyl substances in edible oils

LWT, Год журнала: 2024, Номер 203, С. 116373 - 116373

Опубликована: Июнь 18, 2024

Deep eutectic solvents (DESs) are recognized as sustainable mediums, and DES-related materials have been used for the detection of perfluoroalkyl substances (PFASs). However, such studies were usually limited to only one category PFASs among massive target compounds. Additionally, selectivity related method still needs improvement. In this study, a convenient effective direct selective microextraction multiple was developed based on target-specific DES-based superparamagnetic nanofluid. Parameters DES compositions, amount nanofluid, time systematically investigated establish straightforward, rapid, sensitive, efficient green pretreatment method. Under optimal conditions, demonstrated high sensitivity, good precision, limit 0.04–8.71 ng kg−1, spike recovery 80.49–119.95%, low matrix effects (<20%). The potential mechanism elucidated by ab initio molecular dynamics (AIMD) simulations. solvent system exhibited diverse interaction modes with analytes varying types, including hydrogen bond acceptors (HBA)···PFASs, HBA···FAAs···hydrogen donors (HBD), hetero-halogen interactions. Finally, applied monitoring 13 compounds in 17 edible oil samples, targets detected range 0.05–10.04 kg−1.

Язык: Английский

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Rethinking alternatives to fluorinated pops in aqueous environment and corresponding destructive treatment strategies

The Science of The Total Environment, Год журнала: 2024, Номер 946, С. 174200 - 174200

Опубликована: Июнь 25, 2024

Язык: Английский

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