Transcription factor BbCDR1 regulates the orchestration between conidial formation and maturation in the entomopathogenic fungus Beauveria bassiana
Pest Management Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 24, 2025
Abstract
BACKGROUND
The
entomopathogenic
fungus
Beauveria
bassiana
has
been
widely
used
for
pest
biocontrol
with
conidia
serving
as
the
main
active
agents.
Conidial
yield
and
quality
are
two
important
characteristics
in
fungal
development,
however,
regulatory
mechanisms
that
orchestrate
conidial
formation
development
not
well
understood.
RESULTS
In
this
study,
we
identified
a
Zn
2
Cys
6
transcription
factor
BbCDR1
inhibits
production
while
promoting
maturation.
Compared
wild
type,
ΔBbCDR1
mutant
exhibited
1.88‐fold
increase
but
reduction
quality,
including
decreased
cell
wall
integrity
trehalose
synthesis.
deletion
of
also
led
to
reduced
germination
rates
under
oxidative,
osmotic,
disruption
UV
stresses.
Interestingly,
an
virulence
12.5%
decrease
LT
50
compared
type.
CONCLUSIONS
Further
analysis
revealed
represses
expression
BbbrlA
activates
BbwetA
,
components
central
developmental
pathway
(CDP)
regulate
initiation
maturation,
respectively.
These
findings
suggest
plays
crucial
role
new
target
gene
genetic
engineering
highly
insecticides.
©
2025
Society
Chemical
Industry.
Язык: Английский
A novel fungal sensor (Ngs1) of N-acetylglucosamine (GlcNAc) mediates the fungal response to GlcNAc in the interaction between entomopathogenic Beauveria bassiana and insect host
Journal of Invertebrate Pathology,
Год журнала:
2024,
Номер
unknown, С. 108206 - 108206
Опубликована: Сен. 1, 2024
Язык: Английский
N-acetylglucosamine sensor, Ngs1 contributes to Beauveria bassiana vegetative growth, oxidative phosphorylation, fungal development, and cell wall integrity during entomopathogen-insect interaction
Pesticide Biochemistry and Physiology,
Год журнала:
2024,
Номер
208, С. 106273 - 106273
Опубликована: Дек. 24, 2024
Язык: Английский