Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review

Frontiers in Nutrition, Год журнала: 2023, Номер 9

Опубликована: Янв. 10, 2023

The yellow polyphenolic pigment known as curcumin, originating from the rhizome of turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, well cooking and food coloring. Recently, biological activities curcumin have thoroughly investigated. studies mainly focused on their antioxidant, antitumor, anti-inflammatory, neuroprotective, hepatoprotective, cardioprotective impacts. This review seeks to provide an in-depth, detailed discussion usage within processing industries its effect health support disease prevention. Curcumin’s bioavailability, bio-efficacy, bio-safety characteristics, side effects quality standards, are also discussed. Finally, curcumin’s multifaceted uses, appeal enhancement, agro-industrial techniques counteracting instability low nanotechnology drug delivery systems increase prospective clinical use tactics all

Язык: Английский

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Smartphone based detection and classification of poultry diseases from chicken fecal images using deep learning techniques

Smart Agricultural Technology, Год журнала: 2023, Номер 4, С. 100221 - 100221

Опубликована: Март 25, 2023

Язык: Английский

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The impacts of animal agriculture on One Health—Bacterial zoonosis, antimicrobial resistance, and beyond

One Health, Год журнала: 2024, Номер 18, С. 100748 - 100748

Опубликована: Май 8, 2024

The industrialization of animal agriculture has undoubtedly contributed to the improvement human well-being by increasing efficiency food production. At same time, it also drastically impacted natural environment and society. One Health initiative emphasizes interdependency health ecosystems, animals, humans. In this paper, we discuss some most profound consequences practices from a perspective. More specifically, focus on impacts host-microbe interactions elaborating how modern affects zoonotic infections, specifically those bacterial origin, concomitant emergence antimicrobial resistance (AMR). A key question underlying these deeply interconnected issues is better prevent, monitor, manage infections in agriculture. To address this, outline approaches mitigate agricultural zoonoses AMR, including development novel treatments as well non-drug comprising integrated surveillance programs policy education regarding stewardship. Finally, touch upon additional major environmental factors within context, welfare, security, safety, climate change. Charting are interwoven comprise complex web agriculture's broad will allow for concerted, multidisciplinary interventions which truly necessary tackle

Язык: Английский

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Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review

Frontiers in Nutrition, Год журнала: 2022, Номер 9

Опубликована: Ноя. 8, 2022

Olive oil production is a significant source of economic profit for Mediterranean nations, accounting around 98 percent global output. usage has increased dramatically in recent years, owing to its organoleptic characteristics and rising knowledge health advantages. The culture olive trees the manufacture industrial table produces enormous volumes solid waste dark liquid effluents, involving leaves, pomace, mill wastewaters. These by-products cause an issue manufacturers pose major environmental concerns. As result, partial reuse, like other agronomical wastes, goal be achieved. Because these are high bioactive chemicals, which, if isolated, might denote components with added value food, cosmetic, nutraceutical sectors, indeed, they include amounts beneficial organic acids, carbohydrates, proteins, fibers, phenolic materials, which distributed differently between various wastes depending on method techniques. However, extraction recovery materials from chosen problem their reasonable value, rigorous detection quantification required. primary aims this review context outline vital chemicals by-products, evaluate main developments extraction, purification, identification, study uses food packaging systems safety problems.

Язык: Английский

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Pharmacological, nutritional and antimicrobial uses of Moringa oleifera Lam. leaves in poultry nutrition: an updated knowledge

Poultry Science, Год журнала: 2022, Номер 101(9), С. 102031 - 102031

Опубликована: Июнь 24, 2022

Recently, developing countries have focused on using innovative feed in poultry nutrition. The plant Moringa oleifera is native to India but grows worldwide tropical and subtropical climates. planted a large scale as it can tolerate severe dry cold conditions. All parts of this be used for commercial or nutritional purposes, has favorable profile. Beneficial phytochemicals, minerals, vitamins are abundant the leaves. leaf extracts treat malnutrition; they also possess anticancer, antioxidant, antidiabetic, antibacterial, anti-inflammatory properties. Further, moringa contains antinutritional substances, such trypsin inhibitors, phytates, tannins, oxalates, cyanide, saponins, which harmful effect mineral protein metabolism. Previous research suggested that including chicken diets boosts their growth productivity. Therefore, review focuses characterization application M. nutrition its potential toxicity. Furthermore, we discuss content, antioxidants meal applicability rations.

Язык: Английский

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The relationship among avian influenza, gut microbiota and chicken immunity: an updated overview

Poultry Science, Год журнала: 2022, Номер 101(9), С. 102021 - 102021

Опубликована: Июнь 26, 2022

The alimentary tract in chickens plays a crucial role immune cell formation and challenges, which regulate intestinal flora sustain extra-intestinal immunity. interaction between pathogenic microorganisms the host commensal microbiota as well variety integrity of gut play vital health disease conditions. Thus, several studies have highlighted importance developing immunity against viral infections chickens. (such different species Lactobacillus, Blautia Bifidobacterium, Faecalibacterium, Clostridium XlVa, members firmicutes) encounters pathogens through mechanisms. digestive is highly reactive environment, infectious can disturb its homeostasis, resulting dysbiosis mucosal infections. Avian influenza viruses (AIV) are zoonotic that lead to severe economic losses pose threat poultry industry worldwide. AIV challenging virus affects integrity, disrupts microbial homeostasis induces inflammatory damage mucosa. H9N2 infection elevates expression proinflammatory cytokines, such interferon (IFN-γ IFNα) interleukins (IL-17A IL-22), increases proliferation proteobacteria, particularly Escherichia coli. On contrary, it decreases certain beneficial bacteria, Enterococcus, Lactobacillus other probiotic microorganisms. In addition, primary gel-forming mucin, endogenous trefoil factor family peptides tight junction proteins (ZO-1, claudin 3, occludin), damage. This review highlights relationship among AIV, chicken.

Язык: Английский

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Dietary supplemental coated essential oils and organic acids mixture improves growth performance and gut health along with reduces Salmonella load of broiler chickens infected with Salmonella Enteritidis

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology, Год журнала: 2023, Номер 14(1)

Опубликована: Июль 1, 2023

Reducing Salmonella infection in broiler chickens by using effective and safe alternatives to antibiotics is vital provide safer poultry meat minimize the emergence of drug-resistant spread salmonellosis humans. This study was first evaluate protective efficacy feeding coated essential oils organic acids mixture (EOA) on infected with Enteritidis (S. Enteritidis, SE), then its action mechanism further explored.A total 480 1-day-old Arbor Acres male were randomly assigned into five treatments six replicates, including non-challenged control fed basal diet (A), SE-challenged (B), SE-infected birds a 300 mg/kg EOA (BL), 500 (BM) 800 (BH), respectively. All challenged groups d 13. RESULTS: Feeding showed reversed ability negative effects caused SE infection, as evidenced decreasing feed conversion rate (FCR) ratio villus height crypt depth (VH/CD) (P < 0.05), obviously intestinal internal organs load along increasing cecal butyric acid-producing bacteria abundance 0.05). Moreover, supplemental different levels notably up-regulated claudin-1 (CLDN-1), occludin (OCLN), zonula occludens-1 (ZO-1), mucin-2 (MUC-2), fatty acid binding protein-2 (FABP-2), nuclear factor kappa-light-chain-enhancer activated B cells (NF-κB), myeloid differential protein-88 (MyD88) interleukin-6 (IL-6) mRNA ileum after challenge, whereas down-regulated toll-like receptor-4 (TLR-4) Linear discriminant analysis combined effect size measurements (LEfSe) that relative g_Butyricicoccus, g_Anaerotruncus g_unclassified_f_Bacillaceae significantly enriched given EOA. Also, phylogenetic investigation communities reconstruction unobserved states (PICRUSt) alpha-linolenic metabolism, metabolism biosynthesis unsaturated group.Our data suggest can be used an strategy ameliorate alleviate broilers.

Язык: Английский

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Holistic Strategies to Control Salmonella Infantis: An Emerging Challenge in the European Broiler Sector

Microorganisms, Год журнала: 2023, Номер 11(7), С. 1765 - 1765

Опубликована: Июль 6, 2023

Salmonella spp. has been globally recognized as one of the leading causes acute human bacterial gastroenteritis resulting from consumption animal-derived products. Enteritidis, S. Typhimurium, and its monophasic variant are main serovars responsible for disease. However, a serovar known Infantis emerged fourth most prevalent associated with A total 95% isolated originate broilers their derived This is strongly an elevated antimicrobial (AMR) multidrug resistance, resistance to disinfectants, increased tolerance environmental mercury, heightened virulence, enhanced ability form biofilms attach host cells. Furthermore, this harbors genes that confer colistin, last-resort antibiotic in medicine, it potential acquire additional transferable AMR against other critically important antimicrobials, posing new significant challenge global public health. review provides overview current status poultry sector, focusing on key virulence factors, including genes, biofilm formation. Additionally, novel holistic strategies controlling along entire food chain presented review.

Язык: Английский

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A global genome dataset for Salmonella Gallinarum recovered between 1920 and 2024

Scientific Data, Год журнала: 2024, Номер 11(1)

Опубликована: Окт. 7, 2024

Salmonella enterica serovar Gallinarum (S. Gallinarum) is an avian-specific pathogen responsible for fowl typhoid, a severe systemic disease with high mortality in chickens. This poses substantial burden to the poultry industry, particularly developing countries like China. However, comprehensive genome datasets on S. are lacking. Here, we present most extensive dataset, comprising 574 well-collated samples. dataset consists of 366 genomes sequenced our laboratory and 208 publicly available genomes, collected from various continents over past century. Using silico prediction, categorized into three distinct biovars. Regarding antimicrobial resistance, 238 strains (41.5%) carried resistance genes (ARGs) total 635 records, while 232 (40.4%) exhibited multi-drug resistance. Mobile genomic elements (MGEs) serve as critical drivers ARGs. Our includes 5,636 MGEs belonging prophages plasmids. expands understanding characteristics Gallinarum, providing valuable resources future studies improve management.

Язык: Английский

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Effects of Salmonella Typhimurium infection on intestinal flora and intestinal tissue arachidonic acid metabolism in Wenchang chickens

Frontiers in Microbiology, Год журнала: 2025, Номер 16

Опубликована: Янв. 24, 2025

Salmonella infections can lead to intestinal inflammation and metabolic disorders in birds. However, whether arachidonic acid (ARA) metabolism is involved -induced remains unclear. This experiment investigated the changes cecal flora ARA Hainan Wenchang chickens infected with S. Typhimurium using 16s rDNA sequencing targeted metabolomics. The results showed that levels of metabolites were increased cecum tissue after infection , including prostaglandin E2 (PGE 2 ), F2α (PGF 2α lipoxin A4 (LXA4), ± 8(9)-EET, 11(12)-EET, 8,9-DiHETrE. content key enzymes for production (Phospholipase A2 PLA2 Cyclooxygenase-2 COX-2) chicken tissues was infection. relative mRNA inflammatory factors also infection, Interferon-γ (IFN-γ), Transforming growth factor-β1 (TGF-β1), Interleukin-4 (IL-4), Interleukin-6 (IL-6). In HD11 cells, use a cyclooxygenase (COX) inhibitor reduced COX-2 PGF induced by effectively response. addition, number beneficial genera (e.g., Bifidobacterium Lactobacillus Odorobacterium ) significantly . present study revealed structure -infected chickens. this demonstrated activates pathway, which turn mediates development provide data support theoretical prevention control avian salmonellosis.

Язык: Английский

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