Improving Perinatal Maternal Mental Health Starts With Addressing Structural Inequities

JAMA Psychiatry, Год журнала: 2022, Номер 79(5), С. 387 - 387

Опубликована: Март 9, 2022

Psychological distress during the perinatal period has increased COVID-19 pandemic.A systematic review of 81 studies (N = 132 917 pregnant or postpartum women; research published prior to January 31, 2021) reported prevalence depression and anxiety ranging from 20% 64% ongoing pandemic. 1Although there is still a need examine more representative samples, large cross-sectional study 1 mostly US women corroborated these findings, reporting clinical levels in 36% compared with an estimated prepandemic 11% 17%.Changes prenatal care childbirth experiences, including lack support delivery recovery, may also contribute heightened feelings distress.Women who gave birth pandemic acute stress response (odds ratio, 1.38; 95% CI, 1.01-1.89),correlating posttraumatic disorder symptoms maternal bonding breastfeeding problems.In this Viewpoint, we focus on potential consequences mental health child development highlight structural inequities that be addressed mitigate psychological improve both well-being.

Язык: Английский

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Pandemic babies: a systematic review of the association between maternal pandemic-related stress during pregnancy and infant development

Neuroscience & Biobehavioral Reviews, Год журнала: 2024, Номер 162, С. 105723 - 105723

Опубликована: Май 16, 2024

The COVID-19 pandemic, with its far-reaching influence on daily life, constituted a highly stressful experience for many people worldwide, jeopardizing individuals' mental health, particularly in vulnerable populations such as pregnant women. While growing body of evidence links prenatal maternal stress to biological and developmental alterations offspring, the specific impact exposure pandemic-related (PRS) infant development remains unclear. A comprehensive literature search was performed October 2023 according PRISMA guidelines, which yielded total 28 records. selected papers investigated vast range outcomes offspring large methodological variations. reviewed studies showed mixed results. Either direct associations between PRS during pregnancy temperament socio-emotional development, or indirect links, mediated by emerged most studies. Furthermore, associated epigenetic brain although were limited number. Collectively, findings contribute deeper understanding role early adverse exposures development.

Язык: Английский

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Hair Cortisol in Young Children with Autism and Their Parents: Associations with Child Mental Health, Eating Behavior and Weight Status

Journal of Autism and Developmental Disorders, Год журнала: 2025, Номер unknown

Опубликована: Янв. 22, 2025

Abstract Children with autism and their parents face daily challenges that may be stressful for both. However, little is known about biological stress (hair cortisol concentrations [HCC]) in these families its connection to children’s health outcomes. This study investigates children associations child mental health, eating behavior BMI. Stress was measured 102 young (101 mothers, 86 fathers) using HCC self-reported parenting (OBVL). Child through symptoms (ADOS-2, SRS-2) problem (CBCL). (CEBQ) BMIz were also measured. had higher than peers. not linked behavior, or BMIz. Maternal (self-reported HCC) associated behavior. In fathers, correlated (SRS-2) problems. Both parents’ specifically emotional undereating overeating. conclusion, levels comparison from the general population, suggest differences stress-regulation autism. Given findings, monitoring research clinical practice could improve our understanding of The association between parental behaviors, underscores importance considering family dynamics (preventive) interventions further addresses physical

Язык: Английский

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Effect of Coping Strategies on Perceived Stress and Hair Cortisol Levels During the COVID‐19 Pandemic According to Sex

Stress and Health, Год журнала: 2025, Номер 41(1)

Опубликована: Фев. 1, 2025

ABSTRACT The COVID‐19 crisis generated subjective and physiological stress, with important interindividual differences. Studies have shown that coping strategies sex modulate although their effects on stress hormones been overlooked. In addition, it remains unknown whether interact to predict these metrics during long‐term stressful events. To examine the impact of strategies, sex, interaction indicators year following arrival virus. Coping were assessed using Brief COPE questionnaire in May 2020. Stress symptoms as a indicator every 3 months (June 2020 March 2021) Perceived Scale 155 participants (49 men). Of individuals, 111 provided 6‐cm hair sample June estimate cortisol levels before first lockdown. A factor analysis identified three clusters strategies: positive‐oriented, avoidance‐oriented, social support. For linear‐mixed model showed women reported more than men. Positive‐oriented avoidance‐oriented associated less respectively. An between indicated positive relationship support perceived However, among men who used this strategy infrequently, higher regression revealed had greater secretion response pandemic. These findings suggest whereas influences stress.

Язык: Английский

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Stress in lockdown: exploring the interplay and effects of cortisol and psychological distress in parent-child dyads

Journal of Neural Transmission, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Язык: Английский

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Determination of Cortisol Levels in a Small Volume of Saliva of COVID-19-Recovering Patients During Treatment with Psychotropic Drugs

Biomedicines, Год журнала: 2025, Номер 13(3), С. 697 - 697

Опубликована: Март 12, 2025

Background/Objectives: Cortisol levels are increased in stressful situations but can also result from a history of COVID-19 infection. Long-term exposure to high cortisol has destructive effect on the CNS (Central Nervous System) and lead depression, among other things. The most commonly used psychotropic drugs reduce concentrations. Methods: aim our study was develop an analytical method determine level hormone small volume saliva (200 µL) patients using CNS-active drugs. Solid-phase extraction isolate analyte, determination performed by liquid chromatography with diode array detector (LC DAD). Results: developed validated. Its linearity determined be range 4–500 ng/mL (R2 > 0.9986) intra- inter-day precision expressed as coefficient variation (CV%) did not exceed 12%. then applied post-COVID-19-recovered healthy volunteers. were 12.24 ± 7.33 recovered 4.11 1.46 subjects, respectively. A comparison results showed that volunteers significantly different statistically. Conclusions: allowed for saliva. Comparison concentration individuals recoveries indicates both groups differed statistically, patients. obtained indicate concentrations

Язык: Английский

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Infant development at 14 months in the context of maternal objective and subjective birth experience and infant hair glucocorticoids

BMC Pediatrics, Год журнала: 2025, Номер 25(1)

Опубликована: Март 14, 2025

Abstract Background Evidence suggests maternal birth experience impacts infant health. Alterations of the infant’s hypothalamus-pituitary-adrenal (HPA) axis are discussed as one possible underlying mechanism. This study aimed to investigate both objective and subjective potential predictors offspring’s hair glucocorticoid concentrations (GCs) development, respectively. Further, we examined role GCs for prospective development in different domains. Methods n = 263 mothers participating cohort DREAM HAIR completed questionnaires about their approximately eight weeks after birth. Additionally, samples from 286 infants were taken around ten days (neonatal GCs) (infant long-term integrated cortisol cortisone levels measured scalp-near 2-cm segments. Infant (communication, gross motor, fine problem-solving, personal-social) was assessed 14 months using Ages Stages Questionnaire − 3 (ASQ-3). Results No significant associations found between or most domains except that a more negative predicted poorer motor skills. linked lower higher cortisol/cortisone ratio, while associated with neonatal cortisol. Lower showed link personal-social development. However, correction multiple testing, only ratio at remained significant. Conclusions Objective aspects may have enduring impact on than perceptions, particularly complications being ratio. Given this indicate reduced enzymatic activity converting its inactive form, results suggest could affect metabolism. robust experiences Further research diverse, at-risk populations is needed clarify these complex relationships.

Язык: Английский

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Maternal pandemic-related stress during pregnancy associates with infants’ socio-cognitive development at 12 months: A longitudinal multi-centric study

PLoS ONE, Год журнала: 2023, Номер 18(4), С. e0284578 - e0284578

Опубликована: Апрель 17, 2023

Background Prenatal maternal stress is a key risk factor for infants’ development. Previous research has highlighted consequences socio-emotional and cognitive outcomes, but less known what regards socio-cognitive In this study, we report on the effects of prenatal related to COVID-19 pandemic 12-month-old behavioral markers Methods Ninety infants their mothers provided complete longitudinal data from birth 12 months. At birth, reported pandemic-related during pregnancy. 12-month-age, remote mother-infant interaction was videotaped: after an initial 2-min face-to-face episode, experimenter remotely played series four auditory stimuli (2 human 2 non-human sounds). The sequence counterbalanced among participants each sound repeated three times every 10 seconds (Exposure, 30 seconds) while were instructed not interact with display neutral still-face expression. Infants’ orienting, communication, pointing toward source coded micro-analytically score (SCS) obtained by means principal component analysis. Results Infants equally oriented stimuli. All Exposure 80% exhibited any communication directed source, 48% showed at least one sound. Mothers who greater had higher probability showing no t = 2.14 ( p .035), or pointing, 1.93 .057). A significant negative linear association found between SCS months, R .07 .010), adjusting potential confounders. Conclusions This study suggests that might have increased altered development in as assessed through observational paradigm Special preventive attention should be devoted born pandemic.

Язык: Английский

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Association between maltreatment, hair cortisol concentration, positive parent–child interaction, and psychosocial outcomes in Chinese preschool children

European Child & Adolescent Psychiatry, Год журнала: 2024, Номер 33(8), С. 2719 - 2730

Опубликована: Янв. 6, 2024

Язык: Английский

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The relationship between hair cortisol concentration and autism diagnosis

Journal of Psychiatric Research, Год журнала: 2024, Номер 176, С. 68 - 76

Опубликована: Май 30, 2024

Autistic children are prone to experience heightened levels of distress and physiological reactivity a range sensory, social, emotional stimuli. In line with this, multiple studies have demonstrated that autistic higher acute cortisol stress responses adverse or threatening stimuli altered awakening responses. However, few examined whether this sensitivity may relate chronic persistently elevated hypothalamic-pituitary-adrenal (HPA) axis activity. The measurement accumulation in hair is considered non-invasive biomarker has been associated several childhood diseases. Here, we investigated concentration large sample differed from non-autistic children, after accounting for child, parental family-level characteristics.

Язык: Английский

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