Scientific Reports,
Год журнала:
2023,
Номер
13(1)
Опубликована: Окт. 17, 2023
Acute
psychosocial
stress
effects
on
inhibition
have
been
investigated
in
young
adults,
but
little
is
known
about
these
older
adults.
The
present
study
of
the
Trier
Social
Stress
Test
cognitive
(i.e.,
ability
to
ignore
distracting
information)
using
a
cross-over
(stress
vs.
control)
design
healthy
(N
=
50;
18-30
years;
Mage
23.06)
versus
adults
65-84
71.12).
Cognitive
was
measured
by
letter
flanker
task
and
psychophysiological
measures
(cortisol,
heart
rate,
subjective
stress)
validated
induction.
results
showed
that
while
impaired
overall
accuracy
across
age
groups
sessions,
(vs.
made
adults'
faster
session
1
slower
2.
Given
2
were
likely
confounded
practice
effects,
suggest
acute
improved
RTs
novel
practiced
task.
That
is,
interaction
between
learning
might
negatively
affect
response
execution
when
testing
tasks.
If
confirmed
future
research,
important
implications
especially
settings
where
repeated
performed
under
stress.
Annals of Behavioral Medicine,
Год журнала:
2025,
Номер
59(1)
Опубликована: Янв. 1, 2025
Medical
illnesses
are
major
stressors
not
only
for
the
patients
but
also
their
family
caregivers,
yet
existing
tools
inadequate
to
assess
mechanistic
response
patterns
such
stressors.
We
sought
validate
a
stress
induction
task
that
pertains
close
relationships
and
health-related
concerns
with
adult
cancer
caregivers.
Patients
newly
diagnosed
colorectal
(n
=
123,
56
years
old,
34%
female,
60%
Hispanic,
6.5
months
post-diagnosis)
caregivers
(55
66%
59%
Hispanic)
underwent
an
experimental
session
during
which
both
individuals
imagined
scenario
where
one
person
is
hit
by
car
(patient)
partner
(caregiver)
has
no
means
provide
or
seek
out
help
victim.
The
consisted
of
6
phases:
baseline,
provision,
speech
preparation,
caregiver,
patient,
recovery.
Results
general
linear
modeling
repeated
measures
revealed
induced
significant
affective,
stress,
cardiovascular
responses
in
Stress
reactivity
recovery
patterns,
however,
varied
versus
phases,
types
assessment.
Findings
suggest
developed
as
acceptable
tool
studying
regulation
medical
contexts.
With
further
validation,
this
may
identify
psychological
physiological
pathways
improve
coping
outcomes
Brain Sciences,
Год журнала:
2025,
Номер
15(3), С. 287 - 287
Опубликована: Март 8, 2025
Background/Objectives:
Suicidal
behaviors
(SBs)
and
non-suicidal
self-injury
(NSSI)
are
significant
mental
health
concerns
in
children
adolescents.
The
hypothalamic–pituitary–adrenal
(HPA)
axis,
of
which
cortisol
is
a
key
hormone,
has
been
implicated
these
behaviors.
This
narrative
review
aims
to
explore
whether
levels
play
role
SBs
NSSI
youth
synthesize
current
evidence
on
this
topic.
Methods:
A
comprehensive
literature
search
was
conducted
studies
published
through
November
2024,
using
PubMed,
Web
Science,
Google
Scholar
databases.
Studies
were
screened
for
eligibility,
including
only
human
English,
with
no
animal
models
or
excluding
levels.
synthesis
approach
used
due
the
methodological
diversity
across
studies.
Due
limited
adolescent-focused
research,
involving
adults
also
considered.
Results:
Findings
indicate
inconsistent
patterns
relation
NSSI.
Elevated
linked
SBs,
some
suggesting
they
may
predict
future
suicide
attempts,
though
definitive
cause-and-effect
relationship
established.
Conversely,
show
mixed
results,
reporting
differences.
Cortisol
responses
stress,
measured
by
saliva,
blood,
hair,
reveal
complex
interactions
psychological
factors
such
as
depression
impulsivity,
influencing
secretion.
Discussion:
Despite
pointing
dysregulation
NSSI,
remains
unclear
study
heterogeneity,
small
sample
sizes
variations.
Gender
type
stressor
complicate
findings.
Future
research
should
prioritize
longitudinal
studies,
better
control
confounding
factors,
utilize
more
diverse
assessment
methods
clarify
links.
Conclusions:
While
pathophysiology
further
needed
establish
clearer,
reliable
patterns.
Identifying
alterations
aid
early
detection
targeted
interventions
at-risk
Neuroscience Applied,
Год журнала:
2024,
Номер
3, С. 104063 - 104063
Опубликована: Янв. 1, 2024
Our
current
understanding
of
the
human
stress
response
and
its
role
in
health,
resilience,
(psycho)pathology
stems
largely
from
acute
studies
controlled
laboratory
settings.
Comparability
findings
across
these
individual
is
comprised,
as
sample
size
are
often
small,
between-individual
variation
large
stress-induction
procedures
measurement
timing
substantial.
To
overcome
this,
16
research
groups
Europe
have
established
STRESS-EU
database.
A
unique
resource
with
participant
data
(n
=
6576)
to
promote
reuse
facilitate
both
meta-analytical
proof-of-principle
analyses
high
statistical
power,
that
can
be
hypothesis-
or
data-driven.
This
short
communication
highlights
structure,
content,
access
contribution
future
plans
database
invited
researchers
worldwide
contribute
this
resource.
Translational Psychiatry,
Год журнала:
2024,
Номер
14(1)
Опубликована: Май 30, 2024
Abstract
Psychological
factors
are
amongst
the
most
robust
predictors
of
healthspan
and
longevity,
yet
rarely
incorporated
into
scientific
medical
frameworks
aging.
The
prospect
characterizing
integrating
psychological
influences
aging
is
therefore
an
unmet
step
for
advancement
geroscience.
Psychogenic
Aging
research
emerging
branch
biogerontology
that
aims
to
address
this
gap
by
investigating
impact
on
human
longevity.
It
interdisciplinary
field
integrates
complex
psychological,
neurological,
molecular
relationships
can
be
best
understood
with
precision
medicine
methodologies.
This
perspective
argues
psychogenic
should
considered
integral
component
Hallmarks
framework,
opening
doors
future
biopsychosocial
integration
in
longevity
research.
By
providing
a
unique
frequently
overlooked
aspects
organismal
aging,
offers
new
insights
targets
anti-aging
therapeutics
individual
societal
levels
significantly
benefit
communities.
Psychoneuroendocrinology,
Год журнала:
2024,
Номер
163, С. 106976 - 106976
Опубликована: Янв. 24, 2024
Researchers
commonly
assess
the
functioning
of
hypothalamic-pituitary-adrenal
(HPA)
axis
by
measuring
natural
fluctuations
its
end
product
cortisol
throughout
day
or
in
response
to
a
standardized
stressor.
Although
it
is
conceivable
that
an
individual
releasing
relatively
more
when
confronted
with
laboratory
stressor
does
same
everyday
life,
inconsistencies
remain
literature
regarding
associations
between
diurnal
parameters
and
stress
responses.
Hence,
current
meta-analysis
aggregated
findings
12
studies
examine
overall
(including
total
output,
slope,
awakening
[CAR])
reactivity
recovery
Trier
Social
Stress
Test
(TSST).
There
were
no
significant
CAR
reactivity.
Lower
output
was
significantly
related
better
recovery,
whereas
slope
unrelated
recovery.
Moderation
analyses
revealed
responses
dependent
on
computation
method
parameters,
questioning
convergence
validity
employed
measures
Overall,
seems
we
cannot
predict
characteristics
rhythm
from
one-time
measure
psychosocial
paradigm.
