Molecular Photoelectrocatalysis for Radical Reactions
Accounts of Chemical Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 13, 2025
ConspectusMolecular
photoelectrocatalysis,
which
combines
the
merits
of
photocatalysis
and
organic
electrosynthesis,
including
their
green
attributes
capacity
to
offer
novel
reactivity
selectivity,
represents
an
emerging
field
in
chemistry
that
addresses
growing
demands
for
environmental
sustainability
synthetic
efficiency.
This
synergistic
approach
permits
access
a
wider
range
redox
potentials,
facilitates
transformations
under
gentler
electrode
decreases
use
external
harsh
reagents.
Despite
these
potential
advantages,
this
area
did
not
receive
significant
attention
until
2019,
when
we
others
reported
first
examples
modern
molecular
photoelectrocatalysis.
These
studies
showcased
immense
hybrid
strategy,
only
inherits
strengths
its
parent
fields
but
also
unlocks
unprecedented
enabling
challenging
mild
conditions
while
minimizing
reliance
on
stoichiometric
oxidants
or
reductants.In
Account,
present
our
efforts
develop
photoelectrocatalytic
strategies
leverage
homogeneous
catalysts
facilitate
diverse
radical
reactions.
By
integrating
electrocatalysis
with
key
photoinduced
processes
such
as
single
electron
transfer
(SET),
ligand-to-metal
charge
(LMCT),
hydrogen
atom
(HAT),
have
established
methods
transform
substrates
organotrifluoroborates,
arenes,
carboxylic
acids,
alkanes
into
reactive
intermediates.
intermediates
subsequently
engage
heteroarene
C-H
functionalization
Importantly,
photoelectrochemical
catalysts,
generated
bulk
solution
readily
participate
efficient
reactions
without
undergoing
further
overoxidation
carbocations,
common
challenge
conventional
electrochemical
systems.By
integration
photoelectrocatalysis
asymmetric
catalysis,
developed
catalysis
(PEAC),
proves
be
enantioselective
synthesis
chiral
nitriles.
involves
two
relay
catalytic
cycles:
initial
process
engenders
benzylic
radicals
from
precursors
alkyl
aryl
alkenes,
C-radicals
are
then
subjected
cyanation
subsequent
copper-electrocatalytic
cycle.Within
realm
oxidative
transformations,
anode
serves
crucial
component
recycling
generating
photocatalyst,
cathode
promotes
proton
reduction.
dual
functionality
enables
via
H
Язык: Английский
Unleashing the potentiality of metals: synergistic catalysis with light and electricity
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(14), С. 4024 - 4040
Опубликована: Янв. 1, 2024
This
review
provides
a
comprehensive
overview
of
metal
catalysis
in
photo-electrochemical
systems,
discussing
reaction
mechanisms
and
offering
prospects
for
this
triadic
catalytic
mode.
Язык: Английский
Enantioselective Remote Alkylation Enabled by Metallaphotoredox Catalysis via Selective C–C Bond Cleavage
ACS Catalysis,
Год журнала:
2025,
Номер
15(3), С. 2212 - 2221
Опубликована: Янв. 23, 2025
Despite
recent
advances
in
enantioselective
radical
coupling
with
strained
cyclic
rings,
asymmetric
reactions
triggered
by
unstrained
motifs
remain
rare.
Herein,
we
report
a
mild
and
general
strategy
for
activating
diverse
set
of
readily
available
alcohols
the
remote
site-specific
allylic
alkylation
ketones
through
combination
photoredox-mediated
proton-coupled
electron
transfer
chiral
chromium
catalysis.
This
newly
developed
dual
catalytic
system
exhibits
extensive
applicability,
operates
under
conditions,
offers
straightforward
operation,
demonstrates
tolerance
to
functional
groups.
The
open-shell
has
also
been
applied
late-stage
modification
complex
drug
natural
product
derivatives
high
levels
enantioselectivity.
Язык: Английский
Decarboxylative Cross-Coupling Enabled by Fe and Ni Metallaphotoredox Catalysis
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(43), С. 29551 - 29559
Опубликована: Окт. 18, 2024
Decarboxylative
cross-coupling
of
carboxylic
acids
and
aryl
halides
has
become
a
key
transformation
in
organic
synthesis
to
form
C(sp
Язык: Английский
α-Thiocyanation of Enol Acetates and Sodium Thiocyanate under Electrochemical Conditions
Chinese Journal of Organic Chemistry,
Год журнала:
2025,
Номер
45(1), С. 189 - 189
Опубликована: Янв. 1, 2025
Язык: Английский
DABCO‐Mediated Photoelectrochemical Three‐Component Sulfonocyclization of 3‐Aza‐1,5‐dienes
Lu-Cai Ding,
Gui-Hong Yang,
Li Luo
и другие.
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 2, 2024
Comprehensive
Summary
Herein,
we
report
a
rare
example
of
three‐component
net‐oxidative
sulfonylation
SO
2
surrogate
with
an
oxidatively
activated
radical
precursor
under
mild
and
metal‐
external‐oxidant‐free
conditions.
The
mildness
sustainability
the
reaction
are
enabled
by
photoelectrocatalysis,
3‐aza‐1,5‐dienes,
organotrifluoroborates
1,4‐diazabicyclo[2.2.2]octane
bis(sulfur
dioxide)
adduct
(DABSO)
undergo
sulfonylative
cyclization
to
afford
sulfono
4‐pyrrolin‐2‐ones
in
atom‐economical
manner
broad
substrate
scope
good
functional‐group
tolerance.
protocol
is
amenable
late‐stage
diversification
complex
molecular
architectures
as
well
gram‐scale
synthesis.
Sunlight
could
be
used
light
source,
conducted
all‐solar
mode
using
commercially
available
photovoltaic
panel
generate
electricity
situ
.
Mechanistic
studies
reveal
that
generated
(DABCO),
which
was
generally
innocent
previous
reactions,
functions
electron
shuttle
between
photocatalytic
cycle
reactants.
Язык: Английский