Association between urinary phthalates and phthalate metabolites and cancer risk: A systematic review and meta-analysis DOI Creative Commons
Meng Meng,

Yao Yang,

Liang Song

и другие.

Heliyon, Год журнала: 2024, Номер 10(8), С. e29684 - e29684

Опубликована: Апрель 1, 2024

Phthalates, widely utilized in industrial products, are classified as endocrine-disrupting chemicals (EDCs). Although certain phthalate and their metabolites have been implicated cancer development, the reported findings exhibited inconsistencies. Therefore, we conducted comprehensive literature search to assess association between risk by identifying original studies measuring phthalates or reporting correlation with until July 4, 2023. The Odds Ratios (ORs) corresponding 95% confidence intervals (CIs) were extracted analyzed estimate risk. Pooled data from eleven studies, including 3101 patients 6858 controls, using a fixed- random-effects model based on heterogeneity tests. When comparing extreme categories of different metabolites, observed significant urinary (MEHHP, MECPP, DBP MBzP) our meta-analysis reinforce existing evidence that is strongly associated development. Further investigations warranted elucidate underlying mechanisms this association. These results may offer novel insights into

Язык: Английский

Organic chemicals associated with rubber are more toxic to marine algae and bacteria than those of thermoplastics DOI Creative Commons
Lisbet Sørensen, Tânia Gomes, A. Igartua

и другие.

Journal of Hazardous Materials, Год журнала: 2023, Номер 458, С. 131810 - 131810

Опубликована: Июнь 9, 2023

The current study investigated the chemical complexity of fifty plastic (36) and elastomer/rubber (14) methanol extracts from consumer products, focusing on association with toxicity in two screening assays (bacteria luminescence marine microalgae). composition varied considerably between products polymers. most complex sample (car tire rubber) contained 2456 features least (disposable water bottle) only 39 features, a median 386 across all products. Individual extract also significantly polymers, showing comparable results terms defining low high extracts, correlation medium extracts. Chemical abundance both correlated assays. However, there were strong differences elastomer Overall, 86-93 % 14 33-36 other polymer (n = 36) more toxic than median. A range compounds tentatively identified set, several concerning being identified, mostly elastomers. While focus chemicals is towards thermoplastics, we show that elastomers may be concern an environmental human health perspective.

Язык: Английский

Процитировано

31

Degradation of dimethyl phthalate by morphology controlled β-MnO2 activated peroxymonosulfate: The overlooked roles of high-valent manganese species DOI
Yanhao Wang,

Yunlong Sun,

Mengchun Gao

и другие.

Journal of Hazardous Materials, Год журнала: 2023, Номер 459, С. 132199 - 132199

Опубликована: Авг. 1, 2023

Язык: Английский

Процитировано

27

Hepatotoxic effects of chronic exposure to environmentally relevant concentrations of Di-(2-ethylhexyl) phthalate (DEHP) on crucian carp: Insights from multi-omics analyses DOI
Yingjie Liu, Shijie You, Lu Ding

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 923, С. 171447 - 171447

Опубликована: Март 4, 2024

Язык: Английский

Процитировано

12

Non-targeted screening and photolysis transformation of tire-related compounds in roadway runoff DOI
Jinfan Chen,

Ting Tang,

Yanxi Li

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 924, С. 171622 - 171622

Опубликована: Март 11, 2024

Язык: Английский

Процитировано

10

Association between urinary phthalates and phthalate metabolites and cancer risk: A systematic review and meta-analysis DOI Creative Commons
Meng Meng,

Yao Yang,

Liang Song

и другие.

Heliyon, Год журнала: 2024, Номер 10(8), С. e29684 - e29684

Опубликована: Апрель 1, 2024

Phthalates, widely utilized in industrial products, are classified as endocrine-disrupting chemicals (EDCs). Although certain phthalate and their metabolites have been implicated cancer development, the reported findings exhibited inconsistencies. Therefore, we conducted comprehensive literature search to assess association between risk by identifying original studies measuring phthalates or reporting correlation with until July 4, 2023. The Odds Ratios (ORs) corresponding 95% confidence intervals (CIs) were extracted analyzed estimate risk. Pooled data from eleven studies, including 3101 patients 6858 controls, using a fixed- random-effects model based on heterogeneity tests. When comparing extreme categories of different metabolites, observed significant urinary (MEHHP, MECPP, DBP MBzP) our meta-analysis reinforce existing evidence that is strongly associated development. Further investigations warranted elucidate underlying mechanisms this association. These results may offer novel insights into

Язык: Английский

Процитировано

10