Radiation Measurements,
Год журнала:
2024,
Номер
176, С. 107213 - 107213
Опубликована: Июнь 21, 2024
In
this
study,
we
examined
the
response
of
Allium
cepa
sprout
stem
cells,
or
meristems,
to
UVB
and
UVC
radiation.
The
choice
cepa,
onion,
was
made
avoid
controversial
use
animal
models.
is
a
well-established
in
vivo
standard
model
that
frequently
used
cytogenetic
research
connected
various
environmental
contaminants.
Indicators
such
as
micronuclei
chromosomal
abnormalities
were
evaluate
genotoxicity
radiation,
mitotic
index
investigate
cytotoxicity
providing
information
on
cellular
proliferation.
Shapiro-Wilk
test
(p
<
0.05)
confirmed
normality
data.
analysis
Pearson
linear
correlation
coefficient
(r
=
0.97),
conducted
across
all
dose
points
considered,
including
negative
control,
revealed
an
almost
perfect
positive
relationship
between
number
cells
with
micronuclei,
for
both
UVC.
frequency
induction
function
radiation
types
found
be
similar.
However,
difference
morphology
exposed
compared
those
observed.
conclusion,
showed
no
significant
differences
cell
activity
irradiation
control
samples.
results
from
study
support
endpoints
biodosimetric
method
ultraviolet
International Journal of Environmental Research and Public Health,
Год журнала:
2021,
Номер
19(1), С. 331 - 331
Опубликована: Дек. 29, 2021
Background:
The
contamination
of
ambulances
with
pathogenic
agents
represents
a
potential
threat
for
the
public
health,
not
only
common
pathogens
but
also
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2).
aim
this
project
was
to
exploits
germicidal
effect
UVC
radiation
at
254
nm
sanitize
patient’s
compartment
an
advanced
UltraViolet
SANitizing
System
(UV-SAN)
and
assess
its
relevance
avoiding
spread
COVID-19
other
drug
resistant
pathogens.
Methods:
system
is
equipped
lamps
that
are
activated
when
ambulance
empty
environment
in
less
than
15
min.
An
Ozone
sensor
continuously
monitors
gas
concentration,
ensuring
it
does
exceed
threshold
value
harmful
patients
operators’
health.
relying
on
GNSS
data
satellite
communication
link,
which
allow
monitor
record
traceability
(when,
where
what)
all
sanitation
operations
performed.
This
information
real-time
monitored
from
dedicated
web-application.
Results:
irradiation
efficiently
reduced
SARS-CoV-2
virus
titer
(>99.99%),
inanimate
surfaces
such
as
plastic,
stainless
steel
or
rubber,
doses
ranging
5.5
24.8
mJ/cm2
UV-SAN
effective
against
multi
(MDR)
bacteria
up
>99.99%,
after
10
30
min
irradiation.
Conclusions:
can
provide
rapid,
efficient
sustainable
sanitization
procedures
ambulances.
Microbiology Spectrum,
Год журнала:
2022,
Номер
10(4)
Опубликована: Авг. 10, 2022
Carbapenem-resistant
Acinetobacter
baumannii
(CRAB),
which
belonged
to
global
clones
1
(GC1)
or
2
(GC2),
has
been
widely
reported
and
become
a
threat.
However,
non-GC1
non-GC2
CRAB
strains
are
not
well-studied,
especially
for
those
with
rare
phenotype.
Here,
one
pyomelanin-producing
strain
(A.
DETAB-R21)
was
isolated
from
oral
swab
in
the
ICU.
Antimicrobial
susceptibility
testing
showed
it
resistant
carbapenems,
ceftazidime,
levofloxacin,
ciprofloxacin.
DETAB-R21
ST164Pas
ST1418Oxf
KL47
OCL5,
respectively.
Whole-genome
sequencing
(WGS)
analysis
revealed
chromosome
contained
three
copies
of
blaOXA-23
on
4,805-bp
Tn2006
composite
transposons
various
novel
9-bp
target
site
duplications
(TSD).
A
Tn125-like
structure,
including
blaNDM-1,
4,343
bp
transposon
encoding
blaCARB-16,
prophage
regions
were
also
identified.
Importantly,
hmgA
interrupted
by
contributed
pyomelanin
production
further
confirmed
overexpression.
Furthermore,
A.
irradiated
UV
light,
higher
relatively
survival
rate
compared
control
that
did
produce
pyomelanin.
No
effects
observed
disinfectants
susceptibility,
growth,
virulence.
In
conclusion,
carrying
blaNDM-1
genes
embedded
bacterial
is
grave
concern
health
care
settings,
highlighting
need
effective
measures
prevent
dissemination.
IMPORTANCE
Pyomelanin
quite
phenotype
baumannii.
Moreover,
mechanisms
leading
still
unclear.
we
first
time,
mechanism
production,
investigated
impact
virulence,
irradiation.
More
importantly,
many
mobile
genetic
elements
(MGEs),
transposons,
copy
structure
regions,
identified
chromosome,
demonstrated
strong
plasticity
genome.
Our
study
provides
important
insights
into
new
high
level
carbapenem
resistance,
great
threat
patients.
These
findings
will
provide
resistance
gene
transfer
via
transposition
events
spread
clinic.
IEEE Transactions on Biomedical Circuits and Systems,
Год журнала:
2023,
Номер
17(5), С. 900 - 915
Опубликована: Май 19, 2023
We
present
a
wirelessly
powered
ultraviolet-C
(UVC)
radiation-based
disinfecting
bandage
for
sterilization
and
treatment
in
chronic
wound
care
management.
The
contains
embedded
low-power
UV
light-emitting
diodes
(LEDs)
the
265
to
285
nm
range
with
light
emission
controlled
via
microcontroller.
An
inductive
coil
is
seamlessly
concealed
fabric
coupled
rectifier
circuit
enable
6.78
MHz
wireless
power
transfer
(WPT).
maximum
WPT
efficiency
of
coils
83%
free
space
75%
on
body
at
coupling
distance
4.5
cm.
Measurements
show
that
UVC
LEDs
are
emitting
radiant
about
0.6
mW
6.8
without
bandage,
respectively,
when
powered.
ability
inactivate
microorganisms
was
examined
laboratory
which
shows
system
can
effectively
eradicate
Gram-negative
bacteria,
Pseudoalteromonas
sp.
D41
strain,
surfaces
six
hours.
proposed
smart
low-cost,
battery-free,
flexible
be
easily
mounted
human
and,
therefore,
great
promise
persistent
infections
care.
Radiation Measurements,
Год журнала:
2024,
Номер
176, С. 107213 - 107213
Опубликована: Июнь 21, 2024
In
this
study,
we
examined
the
response
of
Allium
cepa
sprout
stem
cells,
or
meristems,
to
UVB
and
UVC
radiation.
The
choice
cepa,
onion,
was
made
avoid
controversial
use
animal
models.
is
a
well-established
in
vivo
standard
model
that
frequently
used
cytogenetic
research
connected
various
environmental
contaminants.
Indicators
such
as
micronuclei
chromosomal
abnormalities
were
evaluate
genotoxicity
radiation,
mitotic
index
investigate
cytotoxicity
providing
information
on
cellular
proliferation.
Shapiro-Wilk
test
(p
<
0.05)
confirmed
normality
data.
analysis
Pearson
linear
correlation
coefficient
(r
=
0.97),
conducted
across
all
dose
points
considered,
including
negative
control,
revealed
an
almost
perfect
positive
relationship
between
number
cells
with
micronuclei,
for
both
UVC.
frequency
induction
function
radiation
types
found
be
similar.
However,
difference
morphology
exposed
compared
those
observed.
conclusion,
showed
no
significant
differences
cell
activity
irradiation
control
samples.
results
from
study
support
endpoints
biodosimetric
method
ultraviolet
