Dietary carvacrol essential oil alleviates thallium nitrate-induced toxicity in Oreochromis niloticus: Growth, hepatorenal, oxidative stress, gene expression, and histopathological study

Aquaculture, Год журнала: 2025, Номер unknown, С. 742175 - 742175

Опубликована: Янв. 1, 2025

Язык: Английский

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Source, Occurrence, and Risk Assessment of Antineoplastic Medicines in Aquatic Environments: A Comprehensive Review

Current Pollution Reports, Год журнала: 2023, Номер 9(3), С. 391 - 409

Опубликована: Май 17, 2023

Язык: Английский

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Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells

Biomedicines, Год журнала: 2024, Номер 12(4), С. 855 - 855

Опубликована: Апрель 12, 2024

Aspartame, a widely used artificial sweetener, is present in many food products and beverages worldwide. It has been linked to potential neurotoxicity developmental defects. However, its teratogenic effect on embryonic development the underlying mechanisms need be elucidated. We investigated concentration- time-dependent effects of aspartame zebrafish teratogenicity. focused role sirtuin 1 (SIRT1) Forkhead-box transcription factor (FOXO), two proteins that play key roles neurodevelopment. was found exposure reduced formation larvae cartilage zebrafish. also delayed post-fertilization by altering head length locomotor behavior RNA-sequencing-based DEG analysis showed SIRT1 FOXO3a are involved In silico vitro analyses could target reduce expression neuron cells. Additionally, triggered reduction autophagy flux inhibiting nuclear translocation neuronal The findings suggest can cause defects teratogenicity embryos impairing SIRT1/FOXO3a axis

Язык: Английский

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Environmentally relevant concentrations of F–53B induce eye development disorders-mediated locomotor behavior in zebrafish larvae

Chemosphere, Год журнала: 2022, Номер 308, С. 136130 - 136130

Опубликована: Авг. 29, 2022

Язык: Английский

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Exposure of male adult zebrafish (Danio rerio) to triphenyl phosphate (TPhP) induces eye development disorders and disrupts neurotransmitter system-mediated abnormal locomotor behavior in larval offspring

Journal of Hazardous Materials, Год журнала: 2023, Номер 465, С. 133332 - 133332

Опубликована: Дек. 22, 2023

Язык: Английский

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Integrated physiological, biochemical, and transcriptomic analysis of thallium toxicity in zebrafish (Danio rerio) larvae

The Science of The Total Environment, Год журнала: 2022, Номер 859, С. 160265 - 160265

Опубликована: Ноя. 17, 2022

Язык: Английский

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Cysteamine hydrochloride affects ocular development and triggers associated inflammation in zebrafish

Journal of Hazardous Materials, Год журнала: 2023, Номер 459, С. 132175 - 132175

Опубликована: Июль 27, 2023

Язык: Английский

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Rapid Assessment of Ocular Toxicity from Environmental Contaminants Based on Visually Mediated Zebrafish Behavior Studies

Toxics, Год журнала: 2023, Номер 11(8), С. 706 - 706

Опубликована: Авг. 16, 2023

The presence of contaminants in the environment has increased recent years, and studies have demonstrated that these ability to penetrate blood–retinal barrier directly affect visual systems organisms. Zebrafish are recognized as an ideal model for human eye diseases due their anatomical functional similarities eye, making them efficient versatile organism studying ocular toxicity caused by environmental field toxicology. Meanwhile, zebrafish exhibit a diverse repertoire visually mediated behaviors, system undergoes complex changes behavioral responses when exposed contaminants, enabling rapid assessment induced such pollutants. Therefore, this review aimed highlight effectiveness examining effects on development. Special attention is given behavior zebrafish, which allows resulting from exposure contaminants. Additionally, potential mechanisms may induce briefly outlined.

Язык: Английский

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Early-life exposure to five biodegradable plastics impairs eye development and visually-mediated behavior through disturbing hypothalamus-pituitary-thyroid (HPT) axis in zebrafish larvae

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Год журнала: 2024, Номер 284, С. 109981 - 109981

Опубликована: Окт. 1, 2024

Язык: Английский

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Tea seed saponins ameliorate cyclophosphamide-induced intestinal injury, immune disorder and gut microbial dysbiosis in mice

Food Bioscience, Год журнала: 2023, Номер 57, С. 103504 - 103504

Опубликована: Дек. 22, 2023

Язык: Английский

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