Veterinary Research Communications, Год журнала: 2023, Номер unknown
Опубликована: Фев. 10, 2023
Язык: Английский
International Journal of Environmental Research and Public Health, Год журнала: 2022, Номер 19(24), С. 16830 - 16830
Опубликована: Дек. 15, 2022
Invertebrates have long been an important tool for assessing water pollution due to their characteristics as intermediate consumers in aquatic ecosystem food chains. Most of the time, effects contaminants are measured by effect on oxidative status or mortality, although there already exists easier tool-hemocytes. Hemocytes circulating cells with a very role immune system invertebrates, which can be found within hemolymph, analogous blood vertebrates. The collection hemolymph samples is easy, fast, minimally invasive, and poses no danger life invertebrates. purpose this review was highlight advantages using toxicity assays various substances, including heavy metals, micro- nano-plastics, pesticides, hydrocarbons, oil spills. A literature search conducted most common often used databases, focus recent relevant studies. Bivalve mollusks, crustaceans, gastropods were chosen investigation. This growing number studies choosing use standard methodology toxicology assays, confirming qualities reliable tools.
Язык: Английский
Процитировано
94
Biology, Год журнала: 2023, Номер 12(6), С. 767 - 767
Опубликована: Май 24, 2023
In this historical context, the Mediterranean Sea faces an increasing threat from emerging pollutants such as pharmaceuticals, personal care products, heavy metals, pesticides and microplastics, which pose a serious risk to environment human health. regard, aquatic invertebrates fish are particularly vulnerable toxic effects of these pollutants, several species have been identified bio-indicators for their detection. Among these, bivalve molluscs elasmobranchs now widely used accurately assess contaminants. The study focuses on catshark Scyliorhinus canicular mussel Mytilus galloprovincialis. first one is useful indicator localised contamination levels due its exposure that accumulate seabed. Moreover, it has high trophic position plays important role in ecosystem. mollusc galloprovincialis, other hand, being filter-feeding organism, can acquire bioaccumulate foreign particles present environment. Additionally, because also commercial interest, direct impact conclusion, presence issue requires immediate attention. Bivalve two examples must be precisely determine marine ecosystem
Язык: Английский
Процитировано
79
Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Год журнала: 2023, Номер 270, С. 109645 - 109645
Опубликована: Май 5, 2023
Plastics, long-chain artificial polymers, are used worldwide with a global production of 350 million tonnes per year. Various degradation processes transform plastics into smaller fragments divided micro, meso and macroplastics. In various industries, such as construction, certain plastic additives to improve flexibility enhance performance. Plastic include phthalates (PAE), dibutyl phthalate (DPB) diethyl (DEP). Due the use additives, these small different shapes colours present in all environmental compartments. For their characteristics, PAEs can be introduced particularly by ingestion, inhalation dermal absorption. They accumulate human body, where they have already been identified blood, amniotic fluid urine. The purpose this review is gather effects that on systems body. Being endocrine disruptors, erythrocytes how considered targets for xenobiotics analysed. influence reproductive system was also examined. Phthalates therefore often overused. properties, reach tissues negative impact health. aim give an overview presence hazards. Therefore, should reduced, replaced disposal improved.
Язык: Английский
Процитировано
61
Aquatic Toxicology, Год журнала: 2023, Номер 261, С. 106627 - 106627
Опубликована: Июнь 29, 2023
Enrofloxacin (ENR) is a broad-spectrum antibiotic widely used due to its efficacy against pathogens. Microplastics (MPs) may bind ENR and reduce efficiency, whereas there would be an increase in toxicity, bioavailability, bio-accumulation rates. Therefore, the hypothesis that interaction between MPs can alter their toxicity bioavailability. The subjective of this study examine various concentrations (0, 1.35, 2.7 ml Kg-1 diet) 1000, 2000 mg alone combination for 21 days. rainbow trout (Oncorhynchus mykiss) economic aquaculture species as experimental model ecotoxicology studies. Blood biochemical analytes indicated led increasing enzymatic activity each biomarker, except gamma-glutamyl-transferase (GGT). Alterations related triglycerides, cholesterol, glucose, urea, creatinine, total protein, albumin blood contents were observed. An elevation levels superoxide dismutase (SOD), malondialdehyde (MDA), glucose 6-phosphate dehydrogenase (G6PDH) was found liver. In contrast, catalase (CAT) glutathione peroxidase (GPx) decreased. Furthermore, decline observed cellular antioxidant (ANT) levels. These findings suggested could affect fish health both independently together. Consequently, determined when present high concentrations, amplified, providing further evidence synergistic impact on toxicity.
Язык: Английский
Процитировано
60
The Science of The Total Environment, Год журнала: 2023, Номер 890, С. 164075 - 164075
Опубликована: Май 23, 2023
Caffeine (Caff) is one of the most widely used substances in human diet and a well-recognized drug. Its input into surface waters remarkable, but biological effects on aquatic organisms are unclear, particularly combination with pollutants suspected modulatory activity, like microplastics (MP). The aim this study was to reveal impact marine mussel Mytilus galloprovincialis (Lamark, 1819) Caff (20.0 μg L-1) environmentally relevant (Mix) MP 1 mg L-1 (size 35-50 μm) after exposure for 14 days. Untreated exposed separately groups were also examined. Cell viability cell volume regulation hemocytes digestive cells, as well indexes oxidative stress, glutathione (GSH/GSSG) metallothioneins levels, caspase-3 activity gland assessed. Mix reduced Mn-superoxide dismutase, catalase, S-transferase activities level lipid peroxidation, increased viability, GSH/GSSG ratio (by 1.4-1.5-fold), their Zn content, while did not affect stress metallothionein-related chelation. Protein carbonyls targeted all exposures. distinguishing feature group decline (2-fold) low viability. multi-stress effect shown by worsening cells confirmed discriminant analysis biochemical indexes. special capabilities M. sentinel organism make it an excellent bio-indicator reflecting sub-chronic exposures potentially harmful substances. identification modulation individual combined increases need base monitoring programs studies
Язык: Английский
Процитировано
56
Environmental Toxicology and Pharmacology, Год журнала: 2023, Номер 98, С. 104068 - 104068
Опубликована: Янв. 19, 2023
Microplastic (MP) and heating (T) suspected to modulate biological effects of aquatic contaminants. Salinomycin (Sal) is veterinary antibiotic anticancer agent. The goal this study was examine the multistress effect MP, Sal T on bioindicator bivalve mollusc. Unio tumidus were treated with MP (1 mg L-1), (0.6 µg their combination under 18° C (Mix) 25° (MixT) for 14 days. digestive glands analyzed. did not cause changes Mn- Cu,Zn-SOD, lipid peroxidation Cyp-450-depended EROD levels, whereas catalase, GST protein carbonyls (Sal-group) increased compared control. In Mix-group, enzymes, particularly (by 34% 115% respectively) up-regulated. However, in MixT-group, they corresponding control or lesser (EROD, catalase). Our findings emphasize need take into account interactions environmental risk assessment.
Язык: Английский
Процитировано
55
Chemosphere, Год журнала: 2023, Номер 345, С. 140478 - 140478
Опубликована: Окт. 19, 2023
This study investigated the toxicity of polyethylene microplastics (MPs; <0.02 mm) and CuSO4, alone in combination, on freshwater crayfish Pontastacus leptodactylus. In this study, were exposed to PE-MPs (0.0, 0.5, 1 mg L-1) CuSO4·5H2O for a period 28 days. Next, multi-biomarkers, including biochemical, immunological, oxidative stress indicators analyzed. Results showed that co-exposure CuSO4 resulted increased aspartate aminotransferase (AST), alanine (ALT), lactate dehydrogenase (LDH), decreased alkaline phosphatase (ALP), butyrylcholinesterase (BChE), gamma-glutamyl-transferase (GGT). Triglycerides, cholesterol, glucose, albumin content also increased. Although no significant change was observed lysozyme phenoloxidase activities co-exposed 0.5 L-1 MPs their significantly other experimental groups. Oxidative parameters hepatopancreas indicated superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA) levels, but catalase (CAT), glucose 6-phosphate (G6PDH), cellular total antioxidant (TAC). sub-chronic confirmed. The confirmed found higher concentrations led more severe effects. Co-exposure primarily compromised endpoints, showing when both pollutants present concentrations. POX, LYZ, ALP, GGT, LDH, CAT suppressed by MPs. However, synergistic increase measured biomarkers
Язык: Английский
Процитировано
45
The Science of The Total Environment, Год журнала: 2024, Номер 918, С. 170568 - 170568
Опубликована: Фев. 2, 2024
Among personal care products, quaternium-15 is prominently featured as a preservative in items such shampoos, soaps, shaving and cosmetics. The widespread use of these products people's daily routines contributes to release into aquatic ecosystems. In this context, the primary aim study was assess physiological cellular responses digestive gland gills Mytilus galloprovincialis exposure. Cell viability ability cells regulate their volume were evaluated. Additionally, expression genes involved oxidative stress response assessed further substantiate compound's harmful effects. Results indicated significant decrease both RVD (regulatory decrease) capacity when exposed hypotonic solution. Furthermore, impairment cell function corroborated by modulation stress-related gene expression, including SOD, Cat, well Hsp70 CYP4Y1. Similar alterations observed gills, reflecting impaired functionality vital organ well. summary, outcomes provide conclusive evidence toxicity quaternium-15. This underscores urgent need investigate toxicological effects contaminant on ecosystems emphasises necessity limiting containing
Язык: Английский
Процитировано
20
Chemosphere, Год журнала: 2023, Номер 336, С. 139273 - 139273
Опубликована: Июнь 19, 2023
Due to their uncontrolled use, plastics has become an environmental concern, not only for varying dimension but also the potential release of substances such as phthalates (PAEs) and non-phthalates (NPPs) into water. Phthalates are most common plasticizers non-phthalate di (2-ethylhexyl) terephthalate (DEHT) have been lately found in marine environment. Mytilus galloprovincialis is a well-known bioindicator aquatic environments due its ability accumulate wide variety xenobiotics, including plasticizers. Hence, aim this study was evaluate bioaccumulation effects NPP DEHT on M. galloprovincialis. To purpose, following exposure at 1 mg/l (DEHT1) 100 (DEHT100), accumulation tissues total lipids fatty acid (FA) composition, protein content, cell viability, recover volume changes biomarkers oxidative stress were assessed. Mussels able bioaccumulate tissues, with statistically significant increase compared control organisms. Differences FA composition observed after exposure, since C16:0, C18:0, C20:5ω-3 C22:6ω-3 significantly decreased from exposed groups. As result, SFA, MUFA PUFA affected DEHT-exposed Also, varied DEHT100-group. Considering physiological responses, both groups lost return original digestive gland (DG) cells. On other hand, gills DG by exposure. Overall, showed first time that differentially affect mussels, lipid metabolism, well cellular parameters.
Язык: Английский
Процитировано
38
Environmental Toxicology and Pharmacology, Год журнала: 2023, Номер 101, С. 104207 - 104207
Опубликована: Июнь 28, 2023
Язык: Английский
Процитировано
34