The Science of The Total Environment,
Год журнала:
2023,
Номер
907, С. 167811 - 167811
Опубликована: Окт. 16, 2023
In
recent
years,
wastewater-based
epidemiology
(WBE)
has
emerged
as
a
valuable
and
cost-effective
tool
for
monitoring
the
prevalence
of
COVID-19.
Large-scale
efforts
have
been
implemented
in
numerous
countries,
primarily
focusing
on
sampling
at
entrance
wastewater
treatment
plants
(WWTPs)
to
cover
large
population.
However,
finer
spatial
scale,
such
neighborhood
level
(NGBs),
pose
new
challenges,
including
absence
composite
infrastructure
increased
uncertainty
due
dynamics
small
catchments.
This
study
aims
investigate
feasibility
accuracy
WBE
when
deployed
(sampling
sewers)
compared
city
WWTP).
To
achieve
this,
we
specific
stations
intraurban
scale
within
three
NGBs
Barcelona,
Spain.
The
period
covers
5th
6th
waves
COVID-19
Spain,
spanning
from
March
2021
2022,
along
with
WWTP
downstream
NGBs.
results
showed
strong
correlation
between
clinical
cases
SARS-CoV-2
loads
both
NGB
levels.
Notably,
during
wave,
which
was
dominated
by
Delta
variant,
were
higher
than
wave
(Omicron
variant),
despite
lower
number
recorded
wave.
correlations
stronger
level.
early
warning
potential
varied
across
neighborhoods
waves,
some
showing
one-week
others
lacking
any
significant
signal.
Interestingly,
did
not
exhibit
major
differences
among
different
socioeconomic
statuses.
The Science of The Total Environment,
Год журнала:
2024,
Номер
957, С. 177449 - 177449
Опубликована: Ноя. 19, 2024
Wastewater-based
epidemiology
(WBE)
is
an
effective,
non-invasive
method
for
monitoring
the
spread
of
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
by
tracking
viral
prevalence
in
water.
This
study
aimed
to
investigate
presence
SARS-CoV-2
surface
water
Vietnam
over
two
years.
One-step
quantitative
reverse
transcription
polymerase
chain
reaction
(qRT-PCR)
assays
were
employed
quantify
and
its
variant-specific
mutation
sites
(G339D/E484A)
pepper
mild
mottle
virus
(PMMoV)
from
a
total
315
samples
(105
per
type)
compare
with
reported
Coronavirus
disease
2019
(COVID-19)
cases
environmental
factors.
was
detected
38
%
(40/105),
43
(45/105),
39
(41/105)
Sites
A,
B,
C,
respectively,
concentrations
3.0-5.6
log
Food and Environmental Virology,
Год журнала:
2023,
Номер
15(4), С. 331 - 341
Опубликована: Сен. 21, 2023
Abstract
During
the
COVID-19
pandemic,
wastewater
monitoring
has
been
used
to
monitor
levels
of
SARS-CoV-2
RNA
entering
sewerage
system.
In
Italy,
Istituto
Superiore
di
Sanità
coordinated
SARI
project
(Sorveglianza
Ambientale
Reflue
in
Italia)
detect
and
its
variants.
this
study,
concentration
variants
raw
against
cases
was
evaluated
together
with
effect
temperature
precipitation
on
virus
spread.
We
validated
a
predictive
model,
proposed
by
De
Giglio
et
al.,
2021,
establish
number
cases/100,000
inhabitants.
A
receiver
operating
characteristic
curve
model
applied
predict
Poisson
regression
study
rainfall
viral
load.
Apulia,
from
October
2021
December
2022,
we
analyzed
1041
samples,
which
985
(94.6%)
tested
positive
for
SARS-CoV-2.
Median
atmospheric
inversely
proportional
load
wastewater;
no
correlation
found
precipitation.
The
confirmed
that
at
least
11
inhabitants
would
occur
15
days
following
detection
wastewater.
Environmental
surveillance
can
be
map
Water,
Год журнала:
2024,
Номер
16(4), С. 541 - 541
Опубликована: Фев. 9, 2024
Wastewater-based
epidemiology
provides
an
approach
for
assessing
the
prevalence
of
COVID-19
in
a
sewer
service
area.
In
this
study,
SARS-CoV-2
RNA
was
measured
44
wastewater-treatment
plants
varying
sizes
that
sampled
approximately
67%
population
Minnesota,
from
September
2020
through
December
2022.
Various
linear
regression
models
were
investigated
to
predict
weekly
case
count
concentrations
under
various
transformation
and
normalization
methods
which
we
validated
via
cross-validation
averaged
across
all
treatment
plants.
We
find
relationship
between
incidence
wastewater
may
be
plant-specific.
study
storage
time-to-analysis
data
large
effects
temperature,
indicating
collection
have
important
effect
on
utility
validity
infectious
disease
monitoring.
Our
findings
are
any
large-scale
surveillance
program.
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Март 9, 2023
Background
Testing
samples
of
waste
water
for
markers
infectious
disease
became
a
widespread
method
surveillance
during
the
COVID-19
pandemic.
While
these
data
generally
correlate
well
with
other
indicators
national
prevalence,
that
cover
localised
regions
tend
to
be
highly
variable
over
short
time
scales.
Methods
We
introduce
procedure
estimating
realtime
growth
rate
pathogen
prevalence
using
series
from
wastewater
sampling.
The
number
copies
target
gene
found
in
sample
is
modelled
as
time-dependent
random
whose
distribution
estimated
maximum
likelihood.
output
depends
on
hyperparameter
controls
sensitivity
variability
underlying
data.
apply
this
reporting
N1
SARS-CoV-2
collected
at
treatment
works
across
Scotland
between
February
2021
and
2023.
Results
real-time
121
sampling
sites
covering
diverse
range
locations
population
sizes.
find
fitting
natural
determines
its
reliability
detecting
early
stages
an
epidemic
wave.
Applying
hospital
admissions
data,
we
changes
are
detected
average
2
days
earlier
than
Conclusion
provide
robust
generate
reliable
estimates
provides
responsive
situational
awareness
inform
public
health.
The Science of The Total Environment,
Год журнала:
2023,
Номер
907, С. 167811 - 167811
Опубликована: Окт. 16, 2023
In
recent
years,
wastewater-based
epidemiology
(WBE)
has
emerged
as
a
valuable
and
cost-effective
tool
for
monitoring
the
prevalence
of
COVID-19.
Large-scale
efforts
have
been
implemented
in
numerous
countries,
primarily
focusing
on
sampling
at
entrance
wastewater
treatment
plants
(WWTPs)
to
cover
large
population.
However,
finer
spatial
scale,
such
neighborhood
level
(NGBs),
pose
new
challenges,
including
absence
composite
infrastructure
increased
uncertainty
due
dynamics
small
catchments.
This
study
aims
investigate
feasibility
accuracy
WBE
when
deployed
(sampling
sewers)
compared
city
WWTP).
To
achieve
this,
we
specific
stations
intraurban
scale
within
three
NGBs
Barcelona,
Spain.
The
period
covers
5th
6th
waves
COVID-19
Spain,
spanning
from
March
2021
2022,
along
with
WWTP
downstream
NGBs.
results
showed
strong
correlation
between
clinical
cases
SARS-CoV-2
loads
both
NGB
levels.
Notably,
during
wave,
which
was
dominated
by
Delta
variant,
were
higher
than
wave
(Omicron
variant),
despite
lower
number
recorded
wave.
correlations
stronger
level.
early
warning
potential
varied
across
neighborhoods
waves,
some
showing
one-week
others
lacking
any
significant
signal.
Interestingly,
did
not
exhibit
major
differences
among
different
socioeconomic
statuses.