Global, regional, and national burden of chronic kidney disease, 1990-2021: a systematic analysis for the global burden of disease study 2021

Frontiers in Endocrinology, Год журнала: 2025, Номер 16

Опубликована: Март 5, 2025

Chronic kidney disease (CKD) continues to represent a significant public health concern, with both prevalence and incidence rates on the rise globally. Therefore, study employed Global Burden of Disease (GBD) database investigate global burden CKD from 1990 2021. This utilized data GBD Join-point regression models were developed for estimation average annual percentage change (AAPC) in mortality CKD. Subsequently, stepwise multiple linear analysis was conducted examine trends disability adjusted life years (DALYs) DALYs rate across diverse populations between Moreover, influence age, gender, socio-demographic index (SDI) among patients 2021 examined. Furthermore, projection 2022 2032 also conducted. The AAPC entire period spanning 0.92 2.66, respectively. A notable increase demonstrated over time, indicating growing society since 1990. lowest 5-9 year age group genders, rising thereafter age. Notably, higher males than females. Regions SDI, generally exhibited lower CKD, while less regions, opposite pattern. Additionally, age-standardized would be projected 8,773.85 21.26 per 100,000 individuals, respectively, by 2032. research indicated gradual which might prompt formulation more efficient policies alleviate its burden.

Язык: Английский

---

Lifestyle factors and their relative contributions to longitudinal progression of cardio-renal-metabolic multimorbidity: a prospective cohort study

Cardiovascular Diabetology, Год журнала: 2024, Номер 23(1)

Опубликована: Июль 18, 2024

Abstract Background The role of lifestyle factors and their relative contributions to the development mortality cardio-renal-metabolic multimorbidity (CRMM) remains unclear. Methods A study was conducted with 357,554 UK Biobank participants. CRMM defined as coexistence two or three diseases (CRMDs), including cardiovascular disease (CVD), type 2 diabetes (T2D) chronic kidney (CKD). prospective examined associations individual combined scores (diet, alcohol consumption, smoking, physical activity, sedentary behavior, sleep duration social connection) longitudinal progression from healthy first (FCRMD), then CRMM, ultimately death, using a multistate model. Subsequently, quantile G-computation employed assess contribution each factor. Results During median follow-up 13.62 years, played crucial in all transitions FCRMD, death. hazard ratios (95% CIs) per score increase were 0.91 (0.90, 0.91) 0.90 (0.89, for FCRMD 0.84 (0.83, 0.86), 0.87 (0.86, 0.89), (0.88, 0.93) risk healthy, respectively. Among seven factors, smoking status contributed high proportions whole progression, accounting 19.88–38.10%. High-risk diet largest proportion transition 22.53%. Less-frequent connection 28.81%. When we further consider disease-specific transitions, find that had slightly stronger T2D than CVD CKD. Conclusions Our indicates may have protective effect throughout informing more effective management treatment. Smoking status, diet, pivotal roles specific transitions.

Язык: Английский

---

Association of fine particulate matter (PM2.5) exposure and chronic kidney disease outcomes: a systematic review and meta-analysis

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Янв. 10, 2024

Abstract Several studies have reported an increased risk of chronic kidney disease (CKD) outcomes after long-term exposure (more than 1 year) to particulate matter with aerodynamic diameter ≤ 2.5 µm (PM ). However, the conclusions remain inconsistent. Therefore, we conducted this meta-analysis examine association between PM and CKD outcomes. A literature search was in PubMed, Scopus, Cochrane Central Register Controlled trials, Embase for relevant published until August 10, 2023. The main were incidence prevalence as well end-stage (ESKD). random-effect model meta‐analyses used estimate each outcome among studies. Twenty two identified, including 14 cohort studies, 8 cross-sectional a total 7,967,388 participants. This revealed that 10 μg/m 3 increment significantly associated risks both [adjusted odds ratio (OR) 1.31 (95% confidence interval (CI) 1.24 1.40), adjusted OR CI 1.03 1.67), respectively]. In addition, relationship ESKD is suggestive but not conclusive (adjusted 1.16; 95% 1.00 1.36). had consistent across all subgroups adjustment variables. Our study observed CKD. more dedicated are required show causation warrants urgent action on mitigate global burden

Язык: Английский

---

Effect of pretreatment methods and doping amount of Enteromorpha on the exhaust purification performance of perovskite catalysts used in underground diesel vehicles

Journal of Cleaner Production, Год журнала: 2024, Номер 445, С. 141191 - 141191

Опубликована: Фев. 9, 2024

Язык: Английский

---

Air pollution and risk of 32 health conditions: outcome-wide analyses in a population-based prospective cohort in Southwest China

BMC Medicine, Год журнала: 2024, Номер 22(1)

Опубликована: Сен. 11, 2024

Язык: Английский

---

Protective Role of Vitamin D Receptor Against Mitochondrial Calcium Overload from PM2.5-Induced Injury in Renal Tubular Cells

Redox Biology, Год журнала: 2025, Номер unknown, С. 103518 - 103518

Опубликована: Янв. 1, 2025

Язык: Английский

---

Associations of Long‐Term Exposure to Fine Particulate Constituents With Cardiovascular Diseases and Underlying Metabolic Mediations: A Prospective Population‐Based Cohort in Southwest China

Journal of the American Heart Association, Год журнала: 2024, Номер 13(10)

Опубликована: Май 18, 2024

The health effects of particulate matter with an aerodynamic diameter ≤2.5 μm (PM

Язык: Английский

---

Seasonal analysis of meteorological parameters and air pollutant concentrations in Kolkata: An evaluation of their relationship

Journal of Cleaner Production, Год журнала: 2023, Номер 436, С. 140514 - 140514

Опубликована: Дек. 30, 2023

Язык: Английский

---

Long-Term Exposure to Nitrogen Dioxide and Ozone and Mortality: Update of the WHO Air Quality Guidelines Systematic Review and Meta-Analysis

International Journal of Public Health, Год журнала: 2024, Номер 69

Опубликована: Окт. 18, 2024

We performed a systematic review and meta-analysis on long-term exposure to nitrogen dioxide (NO

Язык: Английский

---

Epidemiological shifts in chronic kidney disease: a 30-year global and regional assessment

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Дек. 18, 2024

Abstract Background Chronic kidney disease (CKD) presents a growing global health challenge, with significant variability in burden across different regions and countries. This study aimed to analyze the trends incidence, prevalence, mortality, disability-adjusted life years (DALYs) for CKD from 1990 2019, utilizing data Global Burden of Disease Study. Methods We conducted an in-depth on age-standardized DALYs CKD, assessed over 30-year period. Additionally, we explored associations between healthcare access quality (HAQ), Socio-Demographic Index (SDI), CKD. Furthermore, detailed analysis six risk factors closely related based these findings, provided strong evidence enhancing management Results In there were 18,986,903 cases average annual percent change (AAPC) 1.82 (95% CI = 1.8 1.82) incidence since 1990. The rate increased 192.45 per 100,000 233.65 2019. Prevalence also rose, total 69,729,430 2019 AAPC 1.19 1.2). Mortality have correspondingly, mortality reaching 18.29 at 41,538,592 showed that higher HAQ levels are associated better outcomes terms lower DALY rates, whereas correlate poorer outcomes. addition, high fasting plasma glucose systolic blood pressure main contributors CKD-related deaths, their population attributable fraction (PAF) significantly decreasing as SDI decreases. Conclusion has past three decades, influenced by demographic changes variations access. Effective public strategies improvements delivery needed address disparities globally.

Язык: Английский

---