ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 14, 2025
Detecting
pathogenic
bacteria
is
crucial
for
controlling
infectious
diseases,
safeguarding
public
health,
and
ensuring
food
water
safety.
The
integration
of
metal-organic
frameworks
(MOFs)
with
aptamers
offers
a
promising
approach
to
enhance
bacterial
detection.
Aptamers
provide
high
specificity
target
recognition,
while
MOFs
contribute
tunable
porous
structures
stability,
forming
robust
biosensors.
This
synergy
improves
sensitivity,
selectivity,
versatility,
enabling
real-time
quantitative
Applications
span
safety,
environmental
monitoring,
point-of-care
diagnostics.
review
highlights
the
significance
aptamer@MOF
biosensors,
discussing
various
detection
techniques
aptamer
immobilization
methods.
It
also
addresses
challenges
like
enhancing
improving
minimizing
interference,
advancing
scalability
real-world
applications.
Additionally,
limitations
such
as
need
miniaturization,
multimode
detection,
multiplex
analysis
are
highlighted.
Future
directions
focus
on
optimizing
design
expanding
applications
overcome
these
limitations.
versatility
potential
biosensors
underscore
their
promise
high-performance
platforms
in
diverse
fields.
Current Research in Biotechnology,
Год журнала:
2024,
Номер
7, С. 100205 - 100205
Опубликована: Янв. 1, 2024
Nanozymes
are
a
class
of
nanoparticles
that
can
mimic
enzyme
activity
and
be
used
for
various
applications
in
modern
clinical
therapy.
It
has
recently
been
observed
nanozymes
have
multi-enzyme
mimicking
activities,
highly
stable,
versatile
easily
modified.
Moreover,
they
high
catalytic
efficiency,
recovery
rates,
improved
substrate
specificity
suitable
mass
production.
The
mechanisms
mainly
include
catalase,
peroxidase,
oxidase,
hydrolase
superoxide
dismutase-like
which
enable
to
as
potential
therapeutics
against
plethora
infectious
lifestyle
disorders.
cancer,
inflammatory
diseases,
neurodegenerative
neurological
disorders,
bacterial,
fungal
viral
infections,
wounds
diseases
associated
with
Reactive
Oxygen
Species.
purpose
writing
this
review
is
provide
comprehensive
compilation
novel
research
work
taken
place
the
last
few
years
regarding
use
We
compiled
kinds
elaborated
on
their
anti-tumorigenic,
antioxidant,
anti-inflammatory,
antibacterial,
antifungal,
antiviral,
neuroprotective
roles.
Their
modes
action
enzymatic
targets
also
discussed.
types
synthesis
summarized,
along
interactions
nanozymes.
Furthermore,
strategies
enhance
compatibility
between
analyzed.
Major
focus
laid
therapeutic
challenges
future
perspectives
using
therapy
debated
later
sections.
Environmental Science & Technology,
Год журнала:
2024,
Номер
58(18), С. 8009 - 8019
Опубликована: Апрель 1, 2024
With
the
increasing
use
of
metal–organic
frameworks
(MOFs),
they
will
inevitably
enter
environment
intentionally
or
unintentionally.
However,
effects
MOFs
on
plant
growth
are
poorly
understood.
Here,
we
investigated
exposure
rhizosphere
to
growth.
MIL-101(Cr)
was
selected
as
a
research
model
due
its
commercial
availability
and
wide
use.
Soybean
plants
at
two-leaf
stage
were
subjected
various
durations
(1–7
days)
concentrations
(0–1000
mg/L)
in
hydroculture
with
control
group
treated
ultrapure
water.
We
found
that
had
positive
effect
soybean
lower
dose
(i.e.,
200
mg/L);
however,
higher
doses
500
1000
mg/L),
it
exhibited
significant
toxicity
growth,
which
is
evidenced
by
leaf
damage.
To
investigate
mechanism
this
effect,
used
Cr
an
indicator
quantify,
track,
image
laser
ablation
inductively
coupled
plasma
mass
spectrometry
(LA-ICP-MS).
Results
indicated
primarily
accumulated
cortex
roots
(up
40
times
than
stems),
limited
translocation
stems
negligible
presence
leaves
cotyledons.
In
addition,
metabolomic
analysis
soybeans
low-dose
could
increase
sucrose
content
promote
while
high
induce
lipid
oxidation
roots.
This
study
provides
valuable
insights
into
ecological
toxicology
underscores
importance
assessing
their
environmental
impact
for
sustainable
agricultural
practices.
Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(16), С. 3807 - 3839
Опубликована: Янв. 1, 2024
This
review
article
explores
the
innovative
field
of
eco-friendly
cyclodextrin-based
coordination
polymers
and
metal-organic
frameworks
(MOFs)
for
transdermal
drug
delivery
in
case
skin
cancer
therapy.
We
critically
examine
significant
advancements
developing
these
nanocarriers,
with
a
focus
on
their
unique
properties
such
as
biocompatibility,
targeted
release,
enhanced
permeability.
These
attributes
are
instrumental
addressing
limitations
inherent
traditional
treatments
represent
paradigm
shift
towards
more
effective
patient-friendly
therapeutic
approaches.
Furthermore,
we
discuss
challenges
faced
optimizing
synthesis
process
large-scale
production
while
ensuring
environmental
sustainability.
The
also
emphasizes
immense
potential
clinical
applications
nanocarriers
therapy,
highlighting
role
facilitating
targeted,
controlled
release
which
minimizes
systemic
side
effects.
Future
could
see
being
customized
to
individual
patient
profiles,
potentially
revolutionizing
personalized
medicine
oncology.
With
further
research
trials,
hold
promise
transforming
landscape
treatment.
this
study,
aim
provide
comprehensive
overview
current
state
outline
future
directions
advancing
development
application
nanocarriers.
Energies,
Год журнала:
2024,
Номер
17(7), С. 1646 - 1646
Опубликована: Март 29, 2024
This
review
extensively
discusses
current
developments
in
bimetallic
nanoparticle–GO
and
nanoparticle–MOF
nanocomposites
as
potential
catalysts
for
HER,
along
with
their
different
synthesis
methodologies,
structural
characteristics,
catalytic
mechanisms.
The
photoelectrocatalytic
performance
of
these
was
also
compared
based
on
parameters
such
Tafel
slope,
density,
onset
potential,
turnover
frequency,
hydrogen
yield,
activation
energy,
stability,
durability.
shows
that
the
commonly
used
metal
alloys
nanoparticle–GO-based
HERs
include
Pt-based
(e.g.,
PtNi,
PtCo,
PtCu,
PtAu,
PtSn),
Pd-based
PdAu,
PdAg,
PdPt)
or
other
combinations,
AuNi,
AuRu,
etc.,
while
most
electrolyte
sources
are
H2SO4
KOH.
For
nanoparticle
MOF-based
catalysts,
PtCu),
PdCu,
PdCr),
Ni-based
NiMo,
NiTi,
NiAg,
NiCo)
took
lead,
KOH
being
frequently
source.
Lastly,
addresses
challenges
prospects,
highlighting
opportunities
further
optimization
technological
integration
promising
alternative
photo/electrocatalysts
future
production
storage.
