ACS Food Science & Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 8, 2024
Many
natural
products
(NPs)
exhibit
strong
antioxidant
activity,
making
them
valuable
for
various
applications.
In
this
context,
the
emergence
of
deep
eutectic
solvents
(DESs)
is
expected
to
help
address
growing
demand
innovative,
efficient,
and
more
sustainable
methods
NPs
extraction.
DESs
are
designer
that
provide
higher
yields
enhance
activity
extracted
phytochemicals
compared
with
conventional
volatile
organic
solvents.
Antioxidant
naturally
occurring
molecules
can
also
form
DESs,
either
as
hydrogen
bond
donors
(HBD)
or
acceptors
(HBA),
creating
DES
(NADES)
inherent
activity.
Thus,
containing
exert
synergistic
effects,
entire
system
a
promising
active
ingredient
food
industry
The
synergy
arises
from
enhanced
solubilization
stabilization
in
through
bonding,
ionic
interactions,
van
der
Waals
forces.
Collectively,
enable
effectively
neutralize
oxidants
(such
ROS
free
radicals)
regulate
their
reactions
other
molecules,
achieving
up
3-fold
increase
extracts
regular
vitro.
This
Account
overviews
wide
range
resources
using
DESs.
activities
HBA,
HBD,
along
advantageous
coupling
extracts,
thoroughly
discussed.
Finally,
we
envisage
future
directions
potential
applications
harnessing
collective
guide
advances
chemistry.
ACS Omega,
Год журнала:
2024,
Номер
9(29), С. 31274 - 31297
Опубликована: Июль 8, 2024
The
extraction
of
bioactive
components
from
natural
sources
has
gained
significant
attention
in
recent
years
due
to
increasing
demand
for
and
functional
constituents
various
industries,
including
pharmaceuticals,
food,
cosmetics.
This
review
paper
aims
provide
a
comprehensive
overview
the
studies
on
extracting
using
different
advanced
techniques.
It
highlights
need
efficient
methods
preserve
these
components'
integrity
bioactivity.
Various
techniques
as
supercritical-fluid
extraction,
microwave-assisted
ultrasound-assisted
subcritical
solvent
solid-phase
microextraction
are
explored
detail,
highlighting
their
principles,
advantages,
limitations.
further
examines
impact
factors
process,
selection,
time,
temperature,
ultrasonication-amplitude,
etc.
Additionally,
emerging
techniques,
such
green
nanotechnology-based
approaches,
discussed,
emphasizing
potential
enhance
efficiency
sustainability
process.
Furthermore,
presents
case
experimental
results
research
articles,
providing
insights
into
applying
specific
components,
phenolics,
flavonoids,
alkaloids,
essential
oils.
discusses
yield,
bioactivity,
utilization
extracted
industries.
Overall,
this
is
valuable
researchers,
scientists,
industry
professionals
interested
sources.
consolidates
current
knowledge
optimization
parameters,
applications,
facilitating
advancements
field
development
innovative
component
Separations,
Год журнала:
2024,
Номер
11(1), С. 35 - 35
Опубликована: Янв. 19, 2024
Global
food
waste
has
a
huge
impact
on
the
environment,
as
it
is
source
of
greenhouse
gas
emissions
and
wasted
natural
resources.
Across
world,
over
30%
lost
or
each
year.
Aside
from
this,
industry,
well,
one
biggest
sources
agro-industrial
by-products,
which
can
be
valorized
used
for
different
purposes.
Such
good
bioactive
organic
compounds
that
extracted
without
altering
their
properties,
where
deep
eutectic
solvents
serve
green
an
excellent
replacement
volatile
solvents.
Isolated
in
innovative
production,
chemical
cosmetics
other
industries.
Deep
have
attracted
extraordinary
attention
due
to
advantages
such
environmental
friendliness,
availability
easy
preparation,
handling
utilization
non-toxic
components
formation.
Due
these
they
are
greener
alternative
classic
many
processes,
including
extractions.
In
this
paper,
we
review
potential
media
extraction
polyphenols,
carbohydrates,
proteins
alkaloids
by-products
industry
waste.
Processes,
Год журнала:
2025,
Номер
13(1), С. 120 - 120
Опубликована: Янв. 5, 2025
This
review
provides
an
overview
of
recent
developments
in
Citrus
aurantium
L.
(sour
or
bitter
orange),
focusing
on
its
bioactive
compounds,
innovative
extraction
techniques,
and
technological
applications.
C.
is
rich
compounds
such
as
flavonoids
(naringin,
hesperidin,
kaempferol,
quercetin),
essential
oils
(β-pinene,
limonene),
vitamin
C,
which
represents
significant
biological
activities
including
antioxidant,
antimicrobial,
anti-inflammatory,
anticancer
effects.
The
discusses
traditional
methods,
solvent
hydrodistillation,
alongside
newer,
eco-friendly
approaches
like
ultrasound-assisted
extraction,
microwave-assisted
supercritical
fluid
natural
deep
eutectic
solvents.
It
also
highlights
cutting-edge
molecular
imprinting
polymer-based
enable
the
more
efficient
enrichment
purification
specific
synephrine.
Finally,
examines
diverse
industrial
applications
these
sectors
foods,
pharmaceuticals,
cosmetics,
while
emphasizing
growing
need
for
sustainable
technologies.
Frontiers in Pharmacology,
Год журнала:
2025,
Номер
15
Опубликована: Янв. 8, 2025
Natural
pigments,
or
natural
colorants,
are
frequently
utilized
in
the
food
industry
due
to
their
diverse
functional
and
nutritional
attributes.
Beyond
color
properties,
these
pigments
possess
several
biological
activities,
including
antioxidant,
anti-inflammatory,
anticancer,
antibacterial,
neuroprotective
effects,
as
well
benefits
for
eye
health.
This
review
aims
provide
a
timely
overview
of
potential
pharmaceutical,
medical,
industries.
Special
emphasis
is
placed
on
emerging
technologies
pigment
extraction
(thermal
technologies,
non-thermal
supercritical
fluid
extraction),
pharmacological
application
intelligent
packaging
colorants.
show
pharmaceutical
prospects.
For
example,
delphinidin
(30
µM)
significantly
inhibited
growth
three
cancer
cell
lines
(B16-F10,
EO771,
RM1)
by
at
least
90%
after
48
h.
Furthermore,
an
antioxidant
agent,
fucoxanthin
highest
concentration
(50
μg/mL)
increased
ratio
glutathione
disulfide
(p
<
0.05).
In
industry,
have
been
used
improve
value
without
altering
sensory
experience.
Moreover,
use
pH-sensitive
freshness
indicators
cutting-edge
technological
advancement.
innovation
could
useful
information
consumers,
increase
shelf
life,
assist
evaluating
quality
packaged
observing
variations
over
time.
However,
presents
certain
challenges,
particularly
regarding
stability
higher
production
costs
compared
synthetic
pigments.
situation
underscores
need
further
investigation
into
alternative
sources
improved
stabilization
methods.
The
instability
emphasizes
tendency
degrade
change
when
exposed
various
external
conditions,
light,
oxygen,
temperature
fluctuations,
pH
levels,
interactions
with
other
substances
matrix.
Applied Sciences,
Год журнала:
2024,
Номер
14(7), С. 2936 - 2936
Опубликована: Март 30, 2024
Herbs
and
agro-food
wastes
are
rich
sources
of
bioactive
compounds
vital
for
organisms
valuable
many
fields
industry.
Therefore,
in
this
study,
green
deep
eutectic
solvents
(DESs)
such
as
choline
chloride/citric
acid
(ChCl:CitA),
glucose/citric
(Gu:CitA),
glucose/urea
(Gu:U),
betaine/citric
(B:CitA),
betaine/urea
(B:U)
at
a
molar
ratio
1:1
ultrasound-assisted
extraction
(UAE)
antioxidants
from
four
herbs
(chamomile—Cha,
lemon
balm—LB,
mint—M,
nettle—N)
two
(buckwheat
husk—BH
chokeberry
pomace—ChoP)
were
proposed.
The
antioxidant
capacity
(AC)
the
obtained
extracts
was
evaluated
utilizing
three
assays:
cupric
reducing
(CUPRAC
=
0.0–429.9
μmol
Trolox
(TE)/g);
2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic
acid)
(ABTS
0.0–146.5
TE/g);
2,2-diphenyl-1-picrylhydrazyl
(DPPH
11.9–170.3
TE/g).
LB
revealed
highest
CUPRAC
(59.3–429.9
TE/g),
ABTS
(30.7–144.3
DPPH
(32.6–170.3
TE/g)
values.
Due
to
lowest
potential
prepared
using
ChCl:CitA
(AC
30.7–59.3
AC
demonstrated
by
based
on
B:U
144.3–429.9
UAE
conditions
new
DES
consisting
ChCl
U
optimized
Box–Behnken
design
(BBD).
Effects
independent
variables,
ratios
(mol/mol),
water
content
(%),
sonication
time
(t)
studied
response
surface
methodology
(RSM).
results
principal
component
analysis
(PCA)
hierarchical
cluster
(HCA)
that
different
DESs
had
great
differences
residues.
Separation Science and Technology,
Год журнала:
2025,
Номер
unknown, С. 1 - 27
Опубликована: Янв. 15, 2025
The
sustainable
extraction
of
natural
antioxidants
from
plants
has
gained
significant
attention
as
a
viable
alternative
to
synthetic
options
in
the
food
industry.
However,
traditional
processes
often
rely
on
hazardous
solvents,
raising
concerns
about
toxicity
and
environmental
impact.
This
review
highlights
transformative
potential
green
solvents
innovative
technologies
advancing
practices
aligned
with
Sustainable
Development
Goals.
Key
findings
include
effectiveness
intensification
techniques,
such
ultrasound-assisted
microwave-assisted
extractions,
enhancing
efficiency
reducing
resource
use.
also
explores
solutions
critical
challenges
like
solvent
recovery
recycling,
promising
approaches
biphasic
systems
situ
methods
demonstrating
industrial
feasibility.
Notably,
this
work
bridges
gap
between
laboratory-scale
research
large-scale
production
by
emphasizing
strategies
improve
process
scalability.
By
synthesizing
current
trends
identifying
future
directions,
offers
unique
insights
into
commercially
for
antioxidant
extraction,
positioning
essential
tools
more
