Inhibition mechanism of Rhizoctonia solani by pectin-coated iron metal-organic framework nanoparticles and evidence of an induced defense response in rice

Journal of Hazardous Materials, Год журнала: 2024, Номер 474, С. 134807 - 134807

Опубликована: Июнь 4, 2024

Язык: Английский

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Effects of Exposure to Different Types of Metal–Organic Framework Nanoparticles on the Gut Microbiota and Liver Metabolism of Adult Zebrafish

ACS Nano, Год журнала: 2024, Номер unknown

Опубликована: Авг. 31, 2024

Metal–organic framework nanoparticles (MOF NPs) have received much attention for their potential use in nanopesticides. However, little is known about the health and environmental risks associated with these materials. In this study, toxicological responses of zebrafish exposed to five MOF NPs short long periods time were evaluated. The acute toxicity results showed that embryos adult was order Cu-MOF > ZIF-90 ZIF-8 Fe-MOF Zr-MOF. Histopathological analysis revealed ZIF-8, ZIF-90, caused liver swelling vacuolization zebrafish. cellular ultrastructure severely damaged mitochondrial structure intestinal epithelial cells cells. 16S rDNA sequencing data all significantly altered dominant microorganisms intestine. microbial markers inflammation, Proteobacteria (Aeromonas, Plesiomonas, Legionella), increased Fe-MOF, Zr-MOF, treatment groups. Metabolomics indicated levels inflammatory promoting factors (Leukotriene E4, 20-hydroxyeicosatetraenoic acid) arachidonic acid metabolism decreased, suppressing (8,9-epoxyeicosatrienoic increased. Metabolites related oxidative stress, such as glutamine, pyridoxamine, l-glutamic vitamin B6 other signaling pathways, reduced. Overall, suggest different had widely varying zebrafish, further should be paid real environment.

Язык: Английский

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Combined application of surfactants and iron-based metal–organic framework nanoparticles for targeted delivery of insecticides

Chemical Engineering Journal, Год журнала: 2024, Номер 488, С. 151193 - 151193

Опубликована: Апрель 10, 2024

Язык: Английский

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Facile Synthesis of Flower-cluster ZIF Nanocarriers: Performance in Controlled Release of Thiamethoxam and Insecticidal Activity

Environmental Research, Год журнала: 2025, Номер 268, С. 120753 - 120753

Опубликована: Янв. 4, 2025

Язык: Английский

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The key role of magnetic iron-to-biochar mass ratios in the dissipation of oxytetracycline and its resistance genes in soils with and without biodegradable microplastics

Journal of Environmental Management, Год журнала: 2025, Номер 377, С. 124658 - 124658

Опубликована: Фев. 27, 2025

Язык: Английский

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Nationwide prediction of pesticide residual levels in soil: Implications on the resulting risk and prioritization framework

Environment International, Год журнала: 2025, Номер 197, С. 109355 - 109355

Опубликована: Март 1, 2025

Pesticides are widely accumulated in agricultural soils China under successive applications, causing negative impacts on non-target species and environmental qualities. However, a nationwide overview of the residual levels pesticides soil, ecological risks to soil lacking. In this study, we calculated geographically gridded concentrations 107 pesticide active ingredients (AIs) based Computational Pesticide Input (CPI) model further assessed biota. end, proposed an integrated usage-impact identify prioritize control usage, risk persistence pesticides. were range from 0.01 mg kg-1 over 185 kg-1. Glyphosate is most prevalent that exists locations. The mostly as medium risk, with extreme high- high found 1 % 21 soils. Supervision management azoxystrbin, boscalid, butachlor chlorpyrifos need be prioritized. results study provide guidance local governments for designation more accurate mitigation strategies across regions.

Язык: Английский

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An eco‐friendly water‐soluble Cu₂O@His for efficient control of citrus canker

Pest Management Science, Год журнала: 2025, Номер unknown

Опубликована: Март 12, 2025

Abstract BACKGROUND Citrus canker, a bacterial disease caused by Xanthomonas citri subsp. (Xcc), is one of the major threats to citrus industry. Inorganic copper (Cu) formulations such as Bordeaux mixture and Kocide 3000 are currently used control canker; however, they poorly water‐soluble have negligible plant transport, making systemic treatment canker difficult. RESULTS This study synthesized Cu 2 O@His one‐pot self‐assembly 2+ histidine for controlling canker. The results showed that had uniform size distribution (≈2.7 nm) good water solubility. It could disrupt cell membrane Xcc enter into cells destroy DNA, thereby inhibiting growth (half maximal inhibitory concentration = 7.4 μg mL −1 ) production virulence factors Xcc. was attributed its excellent dispersibility reactive oxygen species‐inducing ability. therapeutic efficacy transport were much better than those 3000. Additionally, it remarkable biosafety plants earthworms (lethal 50% >> 40 mg kg ). CONCLUSION provides new, eco‐friendly more efficient option control. © 2025 Society Chemical Industry.

Язык: Английский

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Efficacy, Residue Risk, and Soil Ecosystem Safety of Butylidenephthalide for the Control of Peanut Stem Rot

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 9, 2025

Peanut stem rot caused by Sclerotium rolfsii is becoming increasingly severe. Although butylidenephthalide exhibits great antifungal activity against S. rolfsii, its appropriate application strategy unclear. Greenhouse experiments suggested that was suitable to be preventatively applied root drenching at 400 mg/L for three times with an interval of 7 days. In field trials, exhibited efficacy 51.75% after 21 days and increased the peanut yields 9.89%. Butylidenephthalide rapidly dissipated in soil plants (t1/2 = 2.28-3.41 d), no residues detected edible kernels or haulms harvest. showed a strong uptake accumulation ability from (root concentration factor/bioconcentration factor > 1) moderate upward conductivity roots above-ground parts (TFstem+leaf 0.95). low earthworm toxicity stimulated bacterial/actinomycete populations while suppressing fungi soil. Overall, favorable efficacy, residue risks, high safety on ecosystem control rot.

Язык: Английский

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Green synthesis of neem extract and neem oil-based azadirachtin nanopesticides for fall Armyworm control and management

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 295, С. 118168 - 118168

Опубликована: Апрель 1, 2025

The global spread of Fall Armyworm (FAW, Spodoptera frugiperda) has posed significant challenges to crop productivity and food security, with current pest management relying heavily on synthetic pesticides. This study explores the green synthesis neem extract oil-based Azadirachtin nanopesticides using cellulose acetate (CA) as a carrier polymer, focusing their efficacy against FAW. objective was assess whether CA-NEP (neem nanopesticides) CA-NOL oil nanopesticide) formulations were effective at FAW control minimal ecological impact. synthesized by electrospinning concentrations 5 %, 10 20 33 50 % (w/w) characterized Scanning Electron Microscopy Fourier Transform Infrared spectroscopy. content quantified Liquid Chromatography-Mass Spectroscopy. followed first-order, Korsmeyer-Peppas release kinetics, respectively. Feeding bioassays showed high mortality rates, %-50 achieving greater than 40 in less 3 days reaching 100 day five. rates due feeding CA-NOL-treated corn leaves reached after 4 6 days, respectively, for CA-NOL. Placing nanopesticide fibers next seeds during planting significantly reduced leaf damage. lethal dose (LD50) analyses that 13 is optimal concentration control. Environmental safety assessments earthworms no acute or chronic toxicity, indicating suit ecologically sensitive areas. Therefore, these provide promising, eco-friendly alternative sustainable enhanced safety.

Язык: Английский

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Difenoconazole-Loaded Nanostructured Lipid Carriers: Preparation, Characterization, and Evaluation

Pharmaceuticals, Год журнала: 2025, Номер 18(6), С. 780 - 780

Опубликована: Май 23, 2025

Background/Objectives: Difenoconazole (DFC) is a broad-spectrum fungicide. However, its application limited due to poor aqueous solubility. Drugs with low solubility can be better absorbed using nanostructured lipid carriers (NLCs). Hence, the of DFC in an NLC delivery system proposed. Methods: Difenoconazole-loaded (DFC-NLCs) different solid–liquid ratios were prepared by solvent diffusion method. Key physicochemical parameters, including particle diameter, surface charge (zeta potential), drug encapsulation efficiency, and morphological characteristics, systematically characterized. Using Rhizoctonia solani (R. solani) as model strain, inhibitory efficiency DFC-NLC dispersion was compared that commercial dosage forms, such 25% emulsifiable concentrate (DFC-EC) 40% suspension (DFC-SC). Additionally, uptakes dispersions R. further observed fluorescence probe technology. The safety profiles DFC-NLCs forms evaluated zebrafish organism. Acute toxicity studies conducted determine maximum non-lethal concentration (MNLC) 10% lethal (LC10). Developmental performed observe toxic phenotypes. Results: nanometer range (≈200 nm) high zeta potential, spherical shape 69.1 ± 1.8%~95.0 2.6%, loading 7.1 0.3%~9.7 0.6% determined high-performance liquid chromatography coupled tandem mass spectrometry (HPLC-MS/MS). Compared antifungal effect on significantly improved vitro antibacterial experiments (p < 0.05). 50% effective (EC50) values 0.107 mg·L−1 (DFC-NLC), 0.211 (DFC-EC), 0.321 (DFC-SC), respectively. FITC-labeled demonstrated appropriate deliver into pathogen enhance target effect. In assessment studies, exhibited superior profile formulations Conclusions: This study investigates feasibility NLCs systems for poorly water-soluble fungicides, demonstrating their ability efficacy reduce environmental risks.

Язык: Английский

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