
Aquatic Toxicology, Год журнала: 2024, Номер 277, С. 107134 - 107134
Опубликована: Окт. 30, 2024
Язык: Английский
Aquatic Toxicology, Год журнала: 2024, Номер 277, С. 107134 - 107134
Опубликована: Окт. 30, 2024
Язык: Английский
Aquatic Toxicology, Год журнала: 2025, Номер 284, С. 107404 - 107404
Опубликована: Май 9, 2025
Over the last 20 years, tributyltin (TBT) has been reported to cause metabolic disruption in both invertebrates and vertebrates, highlighting need for further detailed analysis of its physiological effects. This study aimed investigate metabolic-disrupting effects TBT from behavioral molecular level. Adult specimens great pond snail (Lymnaea stagnalis) were exposed an environmentally relevant concentration (100 ng L-1) 21 days. After chronic exposure, alterations as well histological, cellular, changes investigated central nervous system, kidney, hepatopancreas. exposure significantly decreased feeding activity, while locomotor activity remained unchanged. At histological level, cellular localization tin was demonstrated all tissues and, addition, characteristic morphological observed kidney Tissue-specific lipid profiles confirmed TBT-induced homeostasis mollusks, characterized by a consistent reduction proportion polyunsaturated fatty acids shift toward more saturated lipids. The expression 17β-hydroxysteroid dehydrogenase type 12 (HSD17B12) enzyme, involved metabolism reduced three after exposure. Our results show that induces significant multi-level Lymnaea, including direct composition. findings also suggest HSD17B12 enzyme plays key role mammals, is likely disruption. Overall, our extends previous studies on mollusks providing novel tissue-specific data highlights complexity evolutionary conserved way
Язык: Английский
Процитировано
0Environmental Pollution, Год журнала: 2024, Номер 357, С. 124399 - 124399
Опубликована: Июнь 19, 2024
Язык: Английский
Процитировано
2Aquatic Toxicology, Год журнала: 2024, Номер 277, С. 107134 - 107134
Опубликована: Окт. 30, 2024
Язык: Английский
Процитировано
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