Targeting ferroptosis as a potential prevention and treatment strategy for aging-related diseases DOI Creative Commons

Taiwei Jiao,

Y. Chen,

Haiyan Sun

и другие.

Pharmacological Research, Год журнала: 2024, Номер 208, С. 107370 - 107370

Опубликована: Авг. 23, 2024

Ferroptosis, an emerging paradigm of programmed cellular necrosis posited in recent years, manifests across a spectrum maladies with profound implications for human well-being. Numerous investigations substantiate that modulating ferroptosis, whether through inhibition or augmentation, plays pivotal role the etiology and control numerous age-related afflictions, encompassing neurological, circulatory, respiratory, other disorders. This paper not only summarizes regulatory mechanisms but also discusses impact ferroptosis on biological processes aging its diseases. Furthermore, it scrutinizes therapeutic strides addressing aging-related conditions modulation ferroptosis. The consolidates existing knowledge potential applications ferroptosis-related pharmacotherapies envisages translational prospects ferroptosis-targeted interventions clinical paradigms.

Язык: Английский

Unraveling the Differential Tolerance Mechanisms of Acropora formosa and Montipora digitata to Benzo[a]pyrene (BaP) Exposure via 4D Proteomics DOI
Kai Yin, Xin Zhang,

Yuebin Pei

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 492, С. 138213 - 138213

Опубликована: Апрель 8, 2025

Язык: Английский

Процитировано

0
Targeting ferroptosis as a potential prevention and treatment strategy for aging-related diseases DOI Creative Commons

Taiwei Jiao,

Y. Chen,

Haiyan Sun

и другие.

Pharmacological Research, Год журнала: 2024, Номер 208, С. 107370 - 107370

Опубликована: Авг. 23, 2024

Ferroptosis, an emerging paradigm of programmed cellular necrosis posited in recent years, manifests across a spectrum maladies with profound implications for human well-being. Numerous investigations substantiate that modulating ferroptosis, whether through inhibition or augmentation, plays pivotal role the etiology and control numerous age-related afflictions, encompassing neurological, circulatory, respiratory, other disorders. This paper not only summarizes regulatory mechanisms but also discusses impact ferroptosis on biological processes aging its diseases. Furthermore, it scrutinizes therapeutic strides addressing aging-related conditions modulation ferroptosis. The consolidates existing knowledge potential applications ferroptosis-related pharmacotherapies envisages translational prospects ferroptosis-targeted interventions clinical paradigms.

Язык: Английский

Процитировано

3