Current Overview of Metal Nanoparticles’ Synthesis, Characterization, and Biomedical Applications, with a Focus on Silver and Gold Nanoparticles

Pharmaceuticals, Год журнала: 2023, Номер 16(10), С. 1410 - 1410

Опубликована: Окт. 4, 2023

Metal nanoparticles (NPs) have garnered considerable attention, due to their unique physicochemical properties, that render them promising candidates for various applications in medicine and industry. This article offers a comprehensive overview of the most recent advancements manufacturing, characterization, biomedical utilization metal NPs, with primary focus on silver gold NPs. Their potential as effective anticancer, anti-inflammatory, antimicrobial agents, drug delivery systems, imaging agents diagnosis treatment variety disorders is reviewed. Moreover, translation therapeutic settings, issue inclusion clinical trials, are assessed light over 30 investigations concentrate administering either or NPs conditions ranging from nosocomial infections different types cancers. paper aims not only examine biocompatibility nanomaterials but also emphasize challenges may limit safe integration into healthcare practices. More than 100 nanomedicines currently market, which justifies ongoing study use medicine. Overall, present review highlight innovative therapeutics field biomedicine, citing some relevant current applications.

Язык: Английский

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Green synthesis of silver nanoparticles using Eupatorium adenophorum leaf extract: characterizations, antioxidant, antibacterial and photocatalytic activities

Chemical Papers, Год журнала: 2023, Номер 77(6), С. 2947 - 2956

Опубликована: Янв. 25, 2023

Язык: Английский

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Green synthesis, characterization, antibacterial, and antifungal activity of copper oxide nanoparticles derived from Morinda citrifolia leaf extract

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Ноя. 1, 2023

Abstract The green methodologies of nanoparticles with plant extracts have received an increase interest. Copper oxide (CuO NPs) been utilized in a many applications the last few decades. current study presents synthesis CuO NPs aqueous extract Morinda citrifolia as stabilizing agent. leaf was mixed solution copper sulphate (CuSO 4 ·5H 2 O) and sodium hydroxide catalyst. UV–visible spectroscopy, FTIR, XRD, SEM, TEM, EDAX analysis were performed to synthesized NPs. Particle size distribution measured dynamic light scattering. highly stable, sphere-like, particles from 20 50 nm. Furthermore, as-formed shown strong antibacterial activity against Gram-positive bacteria ( Bacillus subtilis, Staphylococcus aureus ), Gram-negative Escherichia coli ). revealed similar trend analysed for antifungal activity. zone inhibition fungi evaluated Aspergillus flavus (13.0 ± 1.1), niger (14.3 0.7), Penicillium frequentans (16.8 1.4). According results this investigation, may be used biomedicine replacement agent biological applications.

Язык: Английский

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Sustainable and consumer-centric nanotechnology-based materials: An update on the multifaceted applications, risks and tremendous opportunities

Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 38, С. 101148 - 101148

Опубликована: Апрель 4, 2024

Язык: Английский

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Bio-derived smart nanostructures for efficient biosensors

Current Opinion in Green and Sustainable Chemistry, Год журнала: 2023, Номер 42, С. 100817 - 100817

Опубликована: Апрель 11, 2023

Язык: Английский

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The LOD paradox: When lower isn't always better in biosensor research and development

Biosensors and Bioelectronics, Год журнала: 2024, Номер 264, С. 116670 - 116670

Опубликована: Авг. 13, 2024

Язык: Английский

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Nose-on-Chip Nanobiosensors for Early Detection of Lung Cancer Breath Biomarkers

ACS Sensors, Год журнала: 2024, Номер 9(9), С. 4469 - 4494

Опубликована: Сен. 9, 2024

Lung cancer remains a global health concern, demanding the development of noninvasive, prompt, selective, and point-of-care diagnostic tools. Correspondingly, breath analysis using nanobiosensors has emerged as promising noninvasive nose-on-chip technique for early detection lung through monitoring diversified biomarkers such volatile organic compounds/gases in exhaled breath. This comprehensive review summarizes state-of-the-art breath-based diagnosis employing chemiresistive-module supported by theoretical findings. It unveils fundamental mechanisms biological basis biomarker generation associated with cancer, technological advancements, clinical implementation nanobiosensor-based analysis. explores merits, challenges, potential alternate solutions implementing these settings, including standardization, biocompatibility/toxicity analysis, green sustainable technologies, life-cycle assessment, scheming regulatory modalities. highlights nanobiosensors' role facilitating precise, real-time, on-site leading to improved patient outcomes, enhanced management, remote personalized monitoring. Additionally, integrating biosensors artificial intelligence, machine learning, Internet-of-things, bioinformatics, omics technologies is discussed, providing insights into prospects intelligent sniffing nanobiosensors. Overall, this consolidates knowledge on breathomic biosensor-based screening, shedding light its significance applications advancing medical diagnostics reduce burden hospitals save human lives.

Язык: Английский

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Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

ACS Sustainable Chemistry & Engineering, Год журнала: 2024, Номер 12(28), С. 10296 - 10312

Опубликована: Июль 1, 2024

Climate change is a profound crisis that affects every aspect of life, including public health. Changes in environmental conditions can promote the spread pathogens and development new mutants strains. Early detection essential managing controlling this improving overall health outcomes. This perspective article introduces basic biosensing concepts various biosensors, electrochemical, optical, mass-based, nano single-molecule as important sustainability preventive tools. The discussion also includes how biosensor crucial to minimizing impacts ensuring long-term availability vital technologies resources for healthcare, monitoring, beyond. One promising avenue pathogen screening could be electrical biomolecules at level, some recent developments based on bioelectronics using Scanning Tunneling Microscopy-assisted break junctions (STM-BJ) technique are shown here. Using technique, detected with high sensitivity, eliminating need amplification cell culture steps, thereby enhancing speed efficiency. Furthermore, STM-BJ demonstrates exceptional specificity, accurately detects single-base mismatches, exhibits limit essentially level individual biomolecules. Finally, case made here sustainable they help, paradigm shift needed achieve them, potential applications.

Язык: Английский

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Smart and sustainable nano-biosensing technologies for advancing stress detection and management in agriculture and beyond

Industrial Crops and Products, Год журнала: 2025, Номер 226, С. 120713 - 120713

Опубликована: Фев. 26, 2025

Язык: Английский

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Towards Modern-Age Advanced Sensors for the Management of Neurodegenerative Disorders: Current Status, Challenges and Prospects

ECS Sensors Plus, Год журнала: 2022, Номер 1(4), С. 042401 - 042401

Опубликована: Окт. 4, 2022

Neurodegenerative diseases (NDD) are progressive degenerative disorders of the neurological system with significant social impact worldwide. Their detection at initial stage is necessary to provide proper therapeutic interventions. Biosensors have emerged as one next-generation tools for detecting and monitoring physiochemical changes associated disorders. This article discusses current status challenges different state-of-the-art sensors which can detect NDD biomarkers. A brief overview developing advanced biosensors help nanotechnology integration, mainly polymer-based functional nanomaterials, has been mentioned prospect these management.

Язык: Английский

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