Assessment of Dietary and Lifestyle Quality Among the Romanian Population in the Post-Pandemic Period

Опубликована: Апрель 8, 2024

Background: The pandemic caused by the SARS-CoV-2 virus demonstrated importance of prevention through a healthy diet and lifestyle, most vulnerable people being those with severe chronic conditions, who are overweight, an unbalanced immune system. Methods: evaluation eating habits lifestyle Romanian population in post-pandemic period was carried out based on cross-sectional observational study help questionnaire. Results: 4704 valid answers were registered (3136 female 1568 male respondents). Among respondents, them belong to young population, 2892 between ages 18 40, i.e., 61.5%. Most respondents overweight (1400) obese (780). indicated tendency consume 1-2 meals per day irregularly (p=0.6167). Only 974 adopted diet, 578 lifestyle. Conclusion: present reports low adherence (20.7%) (12.28%), especially among (< 30 years). In current context, it reduced vegetables fruits below daily average recommended nutrition guidelines, towards sedentary behavior, even deficient hydration some respondents; these negative aspects can create long term series nutritional psycho-emotional imbalances. Our results evidence that complex surveys regularly required investigate or deficiencies; moreover, could be helpful further educational measures nutrition, food, environmental safety.

Язык: Английский

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Is Omicron really mild? – Comparative analysis of comorbidities and disease outcomes associated with SARS-CoV-2 Omicron (B.1.1.529) and Delta (B.1.617.2) variants

Indian Journal of Medical Microbiology, Год журнала: 2023, Номер 45, С. 100391 - 100391

Опубликована: Июнь 6, 2023

Multiple variants of SARS-CoV-2 from Alpha to Omicron have an estimated 6.1 million deaths globally till date. These been found vary in transmissibility and severity. The present study deals with comparison morbidity mortality (B.1.1.529) Delta (B.1.617.2) variants. An observational retrospective cohort was conducted on a laboratory confirmed patients diagnosed by qRT-PCR nasopharyngeal swabs periods; April-2021 January-2022; that were sequenced recorded. Patients invited for telephonic interview after voluntary informed consent obtained each participant wherein, the demographics, co-morbidities, oxygen requirement outcomes enquired about. A total 200 patients, 100 period included study. Major comorbidities hypertension, diabetes mellitus pulmonary disease. who succumbed variant (26%) higher as compared (10%); elderly (68 ​± ​9.7 ​years) having significant during variant. increased hypertension (53.8%, 70%), (26.9%, 40%), chronic disease (30.8%, 20%), smoking (15.4%, 40%) infected both variants, respectively. concluded newer strains potential high milder population large, however, proportion adverse outcomes, irrespective

Язык: Английский

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Early shedding of membrane-bounded ACE2 could be an indicator for disease severity in SARS-CoV-2

Biochimie, Год журнала: 2022, Номер 201, С. 139 - 147

Опубликована: Июнь 17, 2022

Язык: Английский

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The Association between Fear of COVID-19 and Health-Related Quality of Life: A Cross-Sectional Study in the Greek General Population

Journal of Personalized Medicine, Год журнала: 2022, Номер 12(11), С. 1891 - 1891

Опубликована: Ноя. 11, 2022

The aim of this cross-sectional study was to assess the level fear related SARS-CoV-2 virus and association fear, sociodemographic clinical characteristics, with health-related quality life (HRQoL). A large sample Greek general population (N = 583) completed validated versions Fear COVID-19 scale (FCV-19s) 12-item Short Form (SF-12), provided data on socio-demographic status, health history protective behaviors. Variables were compared Mann-Whitney Kruskal-Wallis tests associations Spearman’s correlations. Gamma regression models investigated influence COVID-related variables HRQoL. mean FCV-19s score for 18.3 ± 5.6, physical mental component summary scores 50.2 7.9 46.7 10.1, respectively. More expressed by females (p < 0.001), individuals comorbidities 0.01), those contacts not having caught 0.05). Contrastingly, less unvaccinated frequent intake information about pandemic. Item overall negatively associated SF-12 scores, most important predictor both findings from other similar studies could help identify specific groups in need interventions improve their health, which had deteriorated due

Язык: Английский

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Impact of Acute Complications on The Course and Outcome of Severe COVID-19: a Clinical Analysis and Determination of Mortality Predictors

Ukrainian journal of cardiovascular surgery, Год журнала: 2025, Номер 33(1), С. 103 - 111

Опубликована: Март 25, 2025

Aim. To establish the features of clinical picture, structure acute complications and predictors mortality in patients with a severe course COVID-19. Materials methods. 221 who were intensive care unit (ICU) City Clinical Hospital No. 1 Vinnytsia, Ukraine examined period 2020-2023. Among them, 133 (60.2%) survived 88 (39.8%) died as result COVID-19 (p = 0.02). Results. The rate was 39.8%. classified categories 6 7 by WHO, highest observed, (p<0.001). In group deceased patients, there significantly more hypertension (73 (83.0%) vs. 90 (67.7%), p=0.008), coronary heart disease (CHD) (83 (94.3%) 91 (68.4%)), p 0.0001), combination CAD (72 (81.8%) 79 (59.4%), < 0.001). addition, acute/chronic kidney diseases (18 (20.5%) 13 (9.8%), 0.022) cancer common (12 (13.6%) 8 (6.0%)), 0.046). that occurred during stay ICU, experienced higher rates following conditions: stroke (10 (11.4%) 3 (2.3%), 0.006), failure (9 (10.2%) 4 (3.0%), 0.038), pulmonary embolism 0.014), infectious toxic shock (0.8%), 0.001), respiratory distress syndrome (78 (88.6%) (4.5%), endstage renal (62 (80.5%) 82 (62.1%), 0.006). Additionally, among rhythm disturbances, atrial fibrillation prevalent associated lower survival (31 (35.2%) 19 (14.3%), 0.0001). Conclusions. study demonstrated factors include patient age с omorbidity such hypertension, CAD, disorders. Tachyarrhythmias bradyarrhythmias often observed particular, they had frequent AF, which emphasizes its role predictor poor prognosis

Язык: Английский

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Viral Infections in Elderly Individuals: A Comprehensive Overview of SARS-CoV-2 and Influenza Susceptibility, Pathogenesis, and Clinical Treatment Strategies

Vaccines, Год журнала: 2025, Номер 13(4), С. 431 - 431

Опубликована: Апрель 21, 2025

As age increases, the immune function of elderly individuals gradually decreases, increasing their susceptibility to infectious diseases. Therefore, further research on common viral infections in population, especially severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses, is crucial for scientific progress. This review delves into genetic structure, infection mechanisms, impact coinfections with these two viruses provides a detailed analysis reasons increased dual infections. We evaluated clinical manifestations following coinfections, including complications respiratory, gastrointestinal, nervous, cardiovascular systems. Ultimately, we have summarized current strategies prevention, diagnosis, treatment SARS-CoV-2 older adults. Through studies, aim reduce risk provide basis age-related diseases, thereby improving health status.

Язык: Английский

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Informatics-Driven Unsupervised Learning of Comorbidity Clusters for COVID-19 Reinfection Risk: A Finite Mixture Modeling Approach

Informatics in Medicine Unlocked, Год журнала: 2025, Номер unknown, С. 101649 - 101649

Опубликована: Май 1, 2025

Язык: Английский

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Exploring the therapeutic potential of Thymus vulgaris ethanol extract: a computational screening for antimicrobial compounds against COVID-19 induced mucormycosis

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Май 7, 2025

Язык: Английский

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Mechanisms and potential roles of active ingredients of traditional Chinese medicine in the treatment of chronic obstructive pulmonary disease

Journal of Pharmacy and Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Май 12, 2025

Abstract Objectives Chronic obstructive pulmonary disease (COPD) is a respiratory condition with high rates of morbidity and mortality. Recent studies have shown that the increasing research on Traditional Chinese Medicine (TCM) also plays an important role in COPD. The purpose this review to categorize TCM its active ingredients summarize their pharmacological effects. Methods Articles published up December 2024 were searched through PubMed, X-MOL, China National Knowledge Infrastructure. keywords included combination COPD, pharmacologic activity, anti-inflammatory effects, pharmacology, as well vivo vitro studies. Key findings Thus far, we summarized progress mechanisms action ingredients, such flavonoids, terpenoids, phenols, treatment These encompass reduction inflammatory responses lung injury, regulation oxidation-antioxidation balance, modulation cellular apoptosis aging, among other Conclusion demonstrate strong anti-COPD properties. This provides reference for accelerating development herbal components COPD exploring new potential multi-target therapeutic mechanisms. will mitigate geographical limitations using enhance application future management strategies.

Язык: Английский

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The importance of booster vaccination in the context of Omicron wave

Frontiers in Immunology, Год журнала: 2022, Номер 13

Опубликована: Сен. 8, 2022

Omicron (B.1.1.529) was first detected in a sample collected Botswana on November 11, 2021, and has rapidly replaced Delta as the dominant global variant given robust transmissibility. Moreover, it displays lower virulence than other variants. However, pathogenicity of appears to be underestimated view increasing levels herd immunity through natural infection or vaccination. Additionally, volume hospitalizations deaths increase proportion number cases due high transmissibility Omicron. Therefore, vaccination remains an important public health priority. Notably, series mutations spike protein, especially receptor-binding domain N-terminal domain, associated with immune escape capacity, reducing willingness people receive vaccines. Herein, we provide in-depth discussion assess effectiveness second third against variant. On one hand, two-dose program adopted by many countries is insufficient prevent correlated decline vaccine efficacy over time. booster dose significantly increases protective infection. Most importantly, heterologous induces more response homologous dose. under special background this pandemic, there urgent need accelerate vaccination, providing better strategies, combat emerging

Язык: Английский

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