Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Май 19, 2023
Abstract
Olfactory
is
closely
associated
with
many
diseases,
and
sleep
the
foundation
of
good
health.
While
relationship
between
olfactory
has
been
reported
in
numerous
studies,
there
relatively
little
research
on
whether
duration
an
effect
smell,
so
we
aimed
to
evaluate
olfactory.
This
study
used
cross-sectional
data
from
people
over
40
years
old
who
took
part
National
Health
Nutrition
Examination
Survey
2011
2012,
collecting
details
their
severe
duration,
self-report
changes,
several
other
essential
variables.
There
were
2844
participants,
23.7%
(675/2844)
discovering
alterations.
Compared
individuals
less
than
6
hours
sleep,
adjusted
OR
values
for
dysfunction
8
more
0.7
(95%
CI:
0.56–0.88,
p
=
0.003),
0.66
0.52–0.85,
0.001),
respectively.
The
association
L-shaped
curve
(nonlinear,
0.023).
developing
migraine
was
0.89
0.801–0.996,
0.042)
participants
seven
hours/day.
link
US
adults
L-shaped,
inflection
point
roughly
7
Frontiers in Endocrinology,
Год журнала:
2023,
Номер
14
Опубликована: Сен. 22, 2023
The
early
identification
of
modifiable
risk
factors
is
important
for
preventing
kidney
stones
but
determining
causal
associations
can
be
difficult
with
epidemiological
data.
We
aimed
to
genetically
assess
the
causality
between
(lifestyle
factors,
serum
parameters,
and
metabolic
comorbidities)
stones.
Additionally,
we
explore
impact
education
on
its
potential
mediating
pathways.We
conducted
a
two-sample
Mendelian
randomization
(MR)
study
association
44
FinnGen
dataset
initially
explored
relationship
UK
Biobank
was
used
as
validation
set.
Then,
meta-analysis
by
combining
discovery
datasets.
two-step
MR
mediators
their
mediation
proportions
stones.The
combined
results
indicated
that
previous
exposures
may
increase
stones,
including
sedentary
behavior,
urinary
sodium,
sodium/potassium
ratio,
sodium/creatinine
calcium,
25-hydroxyvitamin
D
(25OHD),
estimated
creatinine-based
glomerular
filtration
rate
(eGFRcrea),
GFR
cystatin
C
(eGFRcys),
body
mass
index
(BMI),
waist
circumference,
type
2
diabetes
mellitus
(T2DM),
fasting
insulin,
glycated
hemoglobin,
hypertension.
Coffee
intake,
plasma
caffeine
levels,
educational
attainment,
potassium/creatinine
ratio
decrease
Ranked
proportion,
effect
mediated
five
behavior
(mediation
25.7%),
smoking
initiation
(10.2%),
BMI
(8.2%),
T2DM
(5.8%),
circumference
(3.2%).This
provides
evidence
supporting
many
Sedentary
lifestyles,
obesity,
smoking,
are
in
attainment
Our
suggest
more
attention
should
paid
these
prevent
World Journal of Urology,
Год журнала:
2024,
Номер
42(1)
Опубликована: Апрель 30, 2024
Kidney
stones
exhibit
a
robust
correlation
with
cardiovascular
disease
(CVD).
The
objective
of
this
research
is
to
investigate
the
between
kidney
and
Life's
Essential
8
(LE8),
newly
updated
assessment
health
(CVH),
among
adults
in
United
States.
To
assess
the
association
between
sleep
patterns
and
factors
(sleep
duration,
trouble
sleeping,
disorder)
risk
of
depression
in
older
adults.
A
total
5636
participants
(2754
men
2882
women)
aged
60
years
from
2007–2014
waves
National
Health
Nutrition
Examination
Survey
(NHANES)
were
included.
Sleep
problems,
disorders
assessed
home
by
trained
interviewers
using
Computer-Assisted
Personal
Interviewing
(CAPI)
system.
The
combined
behaviours
referred
to
as
'sleep
(healthy,
intermediate
poor)',
with
a
'healthy
pattern'
defined
sleeping
7–9
h
per
night
no
self-reported
or
disorders.
Intermediate
poor
indicated
1
2–3
respectively.
Baseline
characteristics
analysed
one-way
logistic
regression.
Logistic
multiple
linear
regression
was
used
depressive
symptoms.Conduct
subgroup
analyses
ensure
robustness
findings.
overall
prevalence
7.7%
among
analysed,
rate
women
being
1.6
times
higher
than
men.
adults
pattern
healthy
(OR:
2.28,
95%
CI:
1.71–3.03,
p
<
0.001).
5.60,
4.25–7.39,
findings
robust
after
controlling
for
items
PHQ-9.
This
nationally
representative
survey
showed
relationship
However,
study
population
limited
Americans,
we
recommend
continued
investigation
causal
mechanisms
two
future,
further
expansion
data
sources
order
applicability
Abstract
Objective
To
explore
the
association
between
circadian
syndrome
(CircS)
and
prevalence
of
kidney
stones
in
overweight
people.
Materials
methods
A
cross-sectional
analysis
was
conducted
based
on
NHANES
2007–2018.
Overweight
people
aged
≥
20
years
were
target
population.
Three
multivariable
logistic
regression
models
built
to
examine
CircS
stones.
Subgroup
age,
gender,
race
also
employed.
Interaction
stratification
identify
whether
some
factors
modify
association.
Result
total
4,603
participants
included
study.
The
suggested
that
positively
associated
with
(OR
=
1.422,
95%
CI
1.057
1.912).
subgroup
showed
more
obvious
females
1.604,
1.023
2.516)
or
population
35
49
old
2.739,
1.428
5.254).
Additionally,
same
trend
present
when
Mexican
American
3.834,
1.790
8.215)
other
races
4.925,
1.776
13.656).
interaction
results
above
robust.
Conclusion
people,
especially
as
females,
49,
Americans.
Current Biology,
Год журнала:
2023,
Номер
33(8), С. 1613 - 1623.e5
Опубликована: Март 24, 2023
Chronic
sleep
loss
profoundly
impacts
metabolic
health
and
shortens
lifespan,
but
studies
of
the
mechanisms
involved
have
focused
largely
on
acute
deprivation.
World Journal of Urology,
Год журнала:
2024,
Номер
42(1)
Опубликована: Март 27, 2024
The
incidence
of
kidney
stone
disease
has
increased
worldwide,
resulting
in
high
medical
costs
and
social
burden.
Kidney
shares
some
common
features
with
the
risk
factors
cardiovascular
diseases
(CVDs).
We
investigated
association
between
health
(CVH)
based
on
Life's
Essential
8
(LE8)
score
developed
by
American
Heart
Association
disease.
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Сен. 13, 2024
Our
aim
was
to
assess
the
relationship
between
weight-adjusted
waist
circumference
index
(WWI)
and
prevalence
of
depression
in
older
adult
hypertensive
patients
United
States.
Medicine,
Год журнала:
2024,
Номер
103(20), С. e38210 - e38210
Опубликована: Май 17, 2024
The
purpose
of
our
study
is
to
examine
the
correlation
between
sleep
factors
and
prevalence
kidney
stones
in
US
adults.
A
total
34,679
participants
from
National
Health
Nutrition
Examination
Survey
2007
2018
were
included
analyses.
Sleep
data
collection
included:
presleep
(difficulty
falling
asleep,
onset
latency),
intra-sleep
(risk
index
obstructive
apnea,
restless
leg
syndrome,
difficulty
maintaining
sleep),
post-sleep
(daytime
sleepiness,
non-restorative
schedule
duration,
quality.
Logistic
regression
models
used
analyze
stones.
Among
participants,
overall
incidence
was
9.3%.
presence
asleep
[odds
ratios
[OR],
1.680;
95%
CI,
1.310–2.150],
prolonged
latency
[OR,
1.320;
1.020–1.700]),
(higher
risk
apnea
1.750;
1.500–2.050],
syndrome
1.520;
1.150–1.990],
1.430;
1.130–1.810]),
sleepiness
1.220–1.680],
1.400;
1.110–1.760]),
short
duration
(OR,
1.190;
1.080–1.310),
mediate
quality
1.140;
1.020–1.290),
poor
1.500;
1.310–1.720)
are
linked
occurrence
However,
latency,
bedtime
wake-up
time
not
significantly
associated
with
These
findings
showed
positive
associations
higher
stone
factors.
Frontiers in Medicine,
Год журнала:
2025,
Номер
12
Опубликована: Март 6, 2025
This
study
examined
the
association
between
Life's
Crucial
9
(LC9)
score
and
kidney
stone
prevalence
in
U.S.
adults.
Using
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
spanning
2007
to
2014,
this
cross-sectional
analysis
focused
on
adult
participants
with
onset
or
recurrence.
LC9
scores
were
divided
into
four
quartiles
for
analysis.
Weighted
multivariable
logistic
regression,
restricted
cubic
spline
(RCS)
modeling,
threshold
effect
analysis,
subgroup
analyses
employed
evaluate
relationship
prevalence.
The
included
24,669
an
average
age
of
46.05
±
0.34
years
a
mean
73.76
0.25.
overall
stones
was
8.45%,
while
recurrence
rate
stood
at
2.96%.
Importantly,
each
one-point
increase
score,
incidence
dropped
by
1.2%
(95%
CI:
0.979
0.997,
p
=
0.014).
Compared
lowest
quartile
(Q1),
Q4
group
exhibited
0.305-fold
higher
0.159
0.586,
<
0.001).
Interaction
showed
that
race
gout
significantly
influenced
risk.
Additionally,
curve
fitting
demonstrated
nonlinear
recurrence,
breakpoint
identified
72.777.
An
elevated
correlates
lower
risk
both
formation
Maintaining
optimal
could
be
effective
approach
preventing
stones.
