Cobalt-Nitrogen Co-Doped Carbon Dots For the Colorimetric and Fluorometric Dual-Model Detection of Gallic Acid DOI
Congcong Hu,

Yu Yin,

Chongyang Huang

и другие.

Опубликована: Янв. 1, 2023

Gallic acid (GA), widely used in food and medicine production industries. Herein, a kind of newly synthesized cobalt-nitrogen co-doped carbon dots (Co,N-CDs) with dual functional properties oxidase-like activity photoluminescence property could oxidize the 3,3',5,5'-tetramethylbenzidine (TMB) to oxTMB new absorption peak at 653 nm. In addition, it was found that performed fluorescence-quenching effect on Co,N-CDs 440 nm attributed FRET (Fluorescence resonance energy transfer). Reductive GA reduce TMB, weaken blue color, restore fluorescence Co,N-CDs. Thus, colorimetric fluorometric method for dual-mode detection established. The synthesis dual-signal probe completed single environmental precursor just one step. Simultaneously, reduced limits, broadened linear range improved anti-interference ability. This exhibited satisfactory application prospect actual tea beverages.

Язык: Английский

Recent advances in the development and analytical applications of oxidase-like nanozymes DOI
Min Feng, Xue Li, Xiaodan Zhang

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 166, С. 117220 - 117220

Опубликована: Авг. 3, 2023

Язык: Английский

Процитировано

90

Breaking the pH Limitation of Nanozymes: Mechanisms, Methods, and Applications DOI
Kaizheng Feng, Guancheng Wang, Shi Wang

и другие.

Advanced Materials, Год журнала: 2024, Номер 36(31)

Опубликована: Апрель 14, 2024

Although nanozymes have drawn great attention over the past decade, activities of peroxidase-like, oxidase-like, and catalase-like are often pH dependent with elusive mechanism, which largely restricts their application. Therefore, a systematical discussion on pH-related catalytic mechanisms together methods to overcome this limitation is in need. In review, various exhibiting pH-dependent collected root causes for dependence comprehensively analyzed. Subsequently, regulatory concepts including environment reconstruction direct activity improvement break restriction summarized. Moreover, applications pH-independent sensing, disease therapy, pollutant degradation overviewed. Finally, current challenges future opportunities development suggested. It anticipated that review will promote further design broaden application range higher efficiency.

Язык: Английский

Процитировано

66

Nanozymes: powerful catalytic materials for environmental pollutant detection and degradation DOI

Qiaoqiao Diao,

Xinyu Chen,

Zheng Tang

и другие.

Environmental Science Nano, Год журнала: 2024, Номер 11(3), С. 766 - 796

Опубликована: Янв. 1, 2024

Here we made a critical review on nanozyme-involved detection and degradation of environmental pollutants, the research progress achieved in last five years was emphatically concluded.

Язык: Английский

Процитировано

54

Rational Design of Nanozymes for Engineered Cascade Catalytic Cancer Therapy DOI

Xiuna Jia,

Erkang Wang, Jin Wang

и другие.

Chemical Reviews, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Nanozymes have shown significant potential in cancer catalytic therapy by strategically catalyzing tumor-associated substances and metabolites into toxic reactive oxygen species (ROS) situ, thereby inducing oxidative stress promoting cell death. However, within the complex tumor microenvironment (TME), rational design of nanozymes factors like activity, reaction substrates, TME itself significantly influence efficiency ROS generation. To address these limitations, recent research has focused on exploring that affect activity developing nanozyme-based cascade systems, which can trigger two or more processes tumors, producing therapeutic achieving efficient stable with minimal side effects. This area remarkable progress. Perspective provides a comprehensive overview nanozymes, covering their classification fundamentals. The regulation nanozyme strategies are discussed detail. Furthermore, representative paradigms for successful construction systems treatment summarized focus revealing underlying mechanisms. Finally, we current challenges future prospects development biomedical applications.

Язык: Английский

Процитировано

5

Multifunctional light-controllable nanozyme enabled bimodal fluorometric/colorimetric sensing of mercury ions at ambient pH DOI

Panwang Hu,

Yuhan Tang,

Hengjia Zhu

и другие.

Biosensors and Bioelectronics, Год журнала: 2023, Номер 238, С. 115602 - 115602

Опубликована: Авг. 15, 2023

Язык: Английский

Процитировано

32

Nanozyme-Inhibited SERS Multichannel Paper-Based Sensor Array for the Quantification and Identification of Biothiols and Cancer Cells Based on Three Ag-Based Nanomaterials DOI
Linjie Wang, Yixin Chen,

Yang Ji

и другие.

Analytical Chemistry, Год журнала: 2024, Номер 96(28), С. 11353 - 11365

Опубликована: Июль 6, 2024

Biothiols play essential roles in maintaining normal physiological functions, resisting oxidative stress, and protecting cell health. Establishing an effective reliable sensor array for the accurate quantification discrimination of diverse biothiols is extremely meaningful. In this work, Ag/Mn3O4, Ag3PO4, Ag3Cit with excellent oxidase-mimetic activity surface-enhanced Raman scattering (SERS)-enhanced features have been prepared loaded onto Whatman filter paper (WFP) to build SERS chips as three sensing channels, which can induce 3,3′,5,5′-tetramethylbenzidine (TMB) oxidation SERS-active reporters (TMBox) concurrently generate prominent signals. Nevertheless, addition suppress conversion from TMB TMBox, cause reduction signal TMBox. Interestingly, each channel different TMBox signals' variations due differences inhibition abilities exclusive properties chip, be plotted specific fingerprint patterns biothiol further translated into intuitive two-dimensional (2D) clustering profiles through linear discriminant analysis (LDA) hierarchical cluster (HCA) techniques precise identification these six minimum concentration 1 μM. More importantly, exploited intracellular glutathione (GSH), differentiate between cancer cells based on GSH contents even identify types tumor cells, demonstrating its powerful application prospects disease diagnosis.

Язык: Английский

Процитировано

14

Self-validating photothermal and electrochemical dual-mode sensing based on Hg2+ etching Ti3C2 MXene DOI
Yanxin Zhang, Jing Li, Xiaobing Li

и другие.

Analytica Chimica Acta, Год журнала: 2024, Номер 1303, С. 342525 - 342525

Опубликована: Март 23, 2024

Язык: Английский

Процитировано

10

Biomass spinach-drived metal-free carbon dots-based nanozyme for multimodal nitrite sensing and functionalized by glucose oxidase as ROS amplifiers to enhance tumor therapy DOI
Xiaorui Dong, Wenjun Yan, Dongmei Zhang

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 304, С. 140875 - 140875

Опубликована: Фев. 10, 2025

Язык: Английский

Процитировано

1

Recent advances and trends in innovative biosensor‐based devices for heavy metal ion detection in food DOI

Aihemaitijiang Aihaiti,

Jingkang Wang, Wenrui Zhang

и другие.

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2024, Номер 23(4)

Опубликована: Июнь 25, 2024

Abstract Low‐cost, reliable, and efficient biosensors are crucial in detecting residual heavy metal ions (HMIs) food products. At present, based on distance‐induced localized surface plasmon resonance of noble nanoparticles, enzyme‐mimetic reaction nanozymes, chelation chelators, the constructed optical sensors have attracted wide attention HMIs detection. Besides, enrichment signal amplification strategy nanomaterials construction electrochemical aptamer sensing platforms, developed overcome plague low sensitivity, poor selectivity, inability multiplexed detection strategy. Moreover, along with an in‐depth discussion these different types biosensors, a detailed overview design application innovative devices principles was provided, including microfluidic systems, hydrogel‐based test strip technologies. Finally, challenges that hinder commercial also been mentioned. Overall, this review aims to establish theoretical foundation for developing accurate reliable technologies HMIs, thereby promoting widespread food.

Язык: Английский

Процитировано

6

Matrix redox interference-free nanozyme-amplified detection of Hg2+ using thiol-modified phosphatase-mimetic nanoceria DOI

Panwang Hu,

Jinjin Liu,

Changkun Xia

и другие.

Sensors and Actuators B Chemical, Год журнала: 2023, Номер 401, С. 135030 - 135030

Опубликована: Ноя. 22, 2023

Язык: Английский

Процитировано

11