Photonics Research,
Год журнала:
2024,
Номер
12(9), С. 2018 - 2018
Опубликована: Июнь 21, 2024
Improving
the
functionality
of
an
optical
sensor
on
a
prefabricated
platform
relies
heavily
signal
conditioning
method
that
actively
modulates
signals.
In
this
work,
we
present
for
active
modulation
response
uses
fiber
modal
interferometers
integrated
in
parallel.
Over
broad
frequency
range
1
Hz
to
kHz,
interferometers’
technology
allows
adjustable
amplification,
attenuation,
and
filtering
dynamic
The
suggested
is
also
used
enhance
real-time
fluid
flowmeter.
order
keep
tabs
different
physical
fields,
approach
promotes
creation
self-conditioning
sensing
systems.
Optics & Laser Technology,
Год журнала:
2024,
Номер
175, С. 110882 - 110882
Опубликована: Март 20, 2024
This
article
introduces
an
innovative
sensor
designed
to
explore
the
localized
surface
plasmon
resonance
(LSPR)
effect
using
optical
fiber
technology
for
detection
of
pesticide
Thiram.
The
proposed
configuration
consists
etched
silica
multimode
coated
with
gold
nanoparticle
(AuNP)
layers
able
modulate
reflected
signal.
What
sets
this
apart
is
its
ability
stimulate
LSPR
modes
single
AuNPs,
i.e.
layer,
and
aggregation
states
nanoparticles
or
multilayer.
capability
has
been
demonstrated
through
both
numerical
simulations
experimental
results.
Furthermore,
device
applied
detect
a
specific
pesticide,
Thiram,
serving
as
illustrative
example
chemical
sensing,
concentrations
within
0.1–100
µM,
achieving
low
limit
(LOD)
below
5
nM.
Nano-Micro Letters,
Год журнала:
2024,
Номер
16(1)
Опубликована: Июль 15, 2024
Macrophage
immunotherapy
represents
an
emerging
therapeutic
approach
aimed
at
modulating
the
immune
response
to
alleviate
disease
symptoms.
Nanomaterials
(NMs)
have
been
engineered
monitor
macrophage
metabolism,
enabling
evaluation
of
progression
and
replication
intricate
physiological
signal
patterns.
They
achieve
this
either
directly
or
by
delivering
regulatory
signals,
thereby
mapping
phenotype
effector
functions
through
metabolic
repurposing
customize
fate
for
therapy.
However,
a
comprehensive
summary
regarding
NM-mediated
visualization
coordinated
rewiring
maintain
phenotypic
equilibrium
is
currently
lacking.
This
review
aims
address
gap
outlining
recent
advancements
in
NM-based
immunotherapy.
We
initially
explore
relationship
between
polarization,
disease,
before
delving
into
NM
innovations
that
visualize
activity
elucidate
onset
fine-tune
its
remodeling
macrophage-centered
Finally,
we
discuss
prospects
challenges
immunotherapy,
aiming
accelerate
clinical
translation.
anticipate
will
serve
as
valuable
reference
researchers
seeking
leverage
novel
intervention-matched
immunomodulators
macrophages
other
fields
engineering.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Июнь 7, 2024
A
surface
plasmon
resonance
(SPR)
phenomenon
implemented
via
D-shaped
polymer
optical
fiber
(POF)
is
exploited
to
realize
cortisol
biosensors.
In
this
work,
two
immonosensors
are
designed
and
developed
for
the
qualitative
as
well
quantitative
measurement
of
in
artificial
real
samples.
The
performances
POF-based
biosensors
recognition
achieved
using
different
functionalization
protocols
make
same
antibody
receptor
layer
over
SPR
cysteamine
lipoic
acid,
achieving
a
limit
detection
(LOD)
0.8
pg/mL
0.2
pg/mL,
respectively.
More
specifically,
use
or
acid
changes
distance
between
surface,
improving
sensitivity
at
low
concentrations
about
one
order
magnitude
configuration
based
on
acid.
LODs
both
competitively
with
other
sensor
systems
but
without
need
amplification
sample
treatments.
obtain
selectivity
tests,
cholesterol
testosterone
were
used
interfering
substances.
Moreover,
tests
simulated
seawater
performed
concentration
range
buffer
solution
assess
immunosensor
response
complex
matrix.
Finally,
biosensor
was
estimate
value.
gold
standard
method
has
confirmed
estimated
value
Liquid-liquid
extraction
maximize
liquid
chromatography
coupled
tandem
mass
spectrometry
(LC-MS/MS)
analysis.
ACS Omega,
Год журнала:
2025,
Номер
10(7), С. 6359 - 6367
Опубликована: Фев. 10, 2025
Identification
of
biological
antioxidants
is
vital
importance
because
the
essential
role
in
keeping
balance
various
diseases.
Here,
we
designed
a
simple,
rapid,
and
low-cost
nanozyme
sensing
array
for
colorimetric
identification
multiple
based
on
Au
nanoparticles
(Au
NPs)
synthesized
via
facile
green
aqueous
phase
method.
In
presence
H2O2,
NPs
possessed
peroxidase-like
catalytic
activity
could
effectively
catalyze
color-less
3,3′,5,5′-tetramethylbenzidine
(TMB)
to
blue
oxidized
product
with
comparable
enzyme
kinetics
parameters.
The
function
was
inhibitory
effect
diverse
chromogenic
system
varying
degrees
under
different
pH
conditions,
resulting
"turn-off"
signal
responses.
Based
developed
array,
four
kinds
concentrations
proportions
mixtures
were
successfully
discriminated
from
each
other
aid
principal
component
analysis.
Moreover,
showed
good
performance
differentiating
human
serum
samples,
which
broaden
analytical
application
NPs.
Compared
existing
single
NP-based
significantly
simplified
element
detection
process,
opening
new
avenue
molecule
real
complex
samples.
