ChemBioEng Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 6, 2024
Abstract
The
fast
spread
of
antibiotic‐resistant
bacteria
has
prompted
scientists
to
investigate
alternate
techniques
tackle
infectious
illnesses.
Metal–organic
frameworks
(MOFs)
have
appeared
as
a
favorable
route
for
creating
novel
antibacterial
agents
in
this
area.
This
article
seeks
provide
concise
review
MOFs
prospective
candidate
the
fight
against
bacterial
contamination
and
mechanism
involved
disinfection.
structural
features
that
contribute
their
activity
are
reviewed.
Also,
it
comparatively
analyzes
various
commonly
used
applications
facemasks
discusses
challenges
future
recommendations
increase
efficiency
activity.
It
also
briefs
down
mechanism,
available
scope
applications.
Materials Chemistry Frontiers,
Год журнала:
2023,
Номер
7(8), С. 1684 - 1693
Опубликована: Янв. 1, 2023
2D
Al-TCPP
MOF
nanosheets
were
prepared
via
a
simple
solvothermal
synthesis
method
without
the
need
for
any
surfactants
and
found
to
be
an
effective
sonosensitizer
sonodynamic
cancer
therapy.
Advanced Healthcare Materials,
Год журнала:
2023,
Номер
12(31)
Опубликована: Сен. 14, 2023
Abstract
Although
CeO
2
nanomaterials
have
been
widely
explored
as
nanozymes
for
catalytic
therapy,
they
still
suffer
from
relatively
low
activities.
Herein,
the
catalyzing
generation
and
stabilization
of
oxygen
vacancies
on
nanorods
by
Pt
nanoclusters
via
H
gas
reduction
under
mild
temperature
(350
°C)
to
obtain
Pt/CeO
2−
x
,
which
can
serve
a
highly
efficient
nanozyme
cancer
is
reported.
The
deposited
atomic
layer
deposition
technique
not
only
catalyst
generate
through
hydrogen
spillover
effect,
but
also
stabilize
generated
vacancies.
Meanwhile,
provide
anchoring
sites
forming
strong
metal‐support
interactions
thus
preventing
their
agglomerations.
Importantly,
reduced
at
350
°C
(Pt/CeO
‐350R)
exhibits
excellent
enzyme‐mimicking
activity
reactive
species
(e.g.,
·OH)
compared
other
control
samples,
including
temperatures,
achieving
performance
tumor‐specific
therapy
efficiently
eliminate
cells
in
vitro
ablate
tumors
vivo.
‐350R
originates
good
activities
vacancy‐rich
nanoclusters.
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(9), С. 10998 - 11007
Опубликована: Апрель 29, 2024
Infections
caused
by
bacteria
pose
a
serious
threat
to
public
health,
and
there
is
need
for
numerous
innovative,
antibiotic-free
antimicrobial
medicines.
Herein,
we
describe
the
synthesis
of
CuS/Co-ferrocene-MOF
(CuS/Co-Fc-MOF)
nanocomposites,
formed
coupling
CuS
nanoparticles
(NPs)
two-dimensional
(2D)
Co-Fc-MOF
nanosheets,
that
constitutes
an
platform
capable
near-infrared
(NIR)
photothermal
promotion
chemodynamic
antibacterial.
2D
CuS/Co-Fc-MOF
nanocomposites
consist
nanosheets
with
dimensions
approximately
100–200
nm
thicknesses
13.1–15.6
nm,
where
NPs,
size
about
8
are
excellently
dispersed
on
surface
nanosheets.
The
diverse
valence
states
cobalt
iron
in
enable
them
undergo
Fenton-like
reactions
H2O2,
thus
generating
highly
oxidizing
·OH
therapy
(CDT).
utilization
local
plasmonic
resonance
effect
NPs
enables
enhancement
CDT
activity
under
laser
irradiation.
More
importantly,
can
achieve
rapid
(15
min)
NIR
laser-assisted
killing
both
S.
aureus
E.
coli
bacterial
infection
microenvironment
compared
Therefore,
be
employed
as
promising
nanoagent
promote
photothermally
augmented
antibacterial
therapy.
Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Luminescent
NiMOF
demonstrated
remarkable
capabilities
in
efficient,
sensitive
and
intelligent
detection
of
3-NT
biomarker
6-PTU
thyroid
drug
urine
through
luminescence
quenching
effects.
Molecules,
Год журнала:
2025,
Номер
30(2), С. 251 - 251
Опубликована: Янв. 10, 2025
Climate
change
and
the
energy
crisis,
driven
by
excessive
CO2
emissions,
have
emerged
as
pressing
global
challenges.
The
conversion
of
into
high-value
chemicals
not
only
mitigates
atmospheric
levels
but
also
optimizes
carbon
resource
utilization.
Enzyme-catalyzed
technology
offers
a
green
efficient
approach
to
conversion.
However,
free
enzymes
are
prone
inactivation
denaturation
under
reaction
conditions,
which
limit
their
practical
applications.
Metal-organic
frameworks
(MOFs)
serve
effective
carriers
for
enzyme
immobilization,
offering
porous
crystalline
structures
that
enhance
stability.
Moreover,
high
specific
surface
area
facilitates
strong
gas
adsorption,
making
enzyme@MOF
composites
particularly
advantageous
catalytic
In
this
paper,
we
review
synthesis
technologies
application
enzyme@MOFs
in
Furthermore,
strategies,
including
enhancement
utilization,
coenzyme
regeneration
efficiency,
substrate
mass
transfer
discussed
further
improve
efficiency
aim
is
present
innovative
ideas
future
research
highlight
potential
applications
achieving
Abstract
Although
molybdenum
trioxide
nanomaterials
have
been
widely
explored
as
nanoagents
for
biomedical
applications
against
bacteria
through
photothermal
therapy,
chemodynamic
and
catalytic
their
utilization
photosensitizers
photodynamic
therapy
(PDT)
rarely
reported
so
far.
Herein,
we
report
the
activation
of
MoO
3
nanobelts
via
aqueous
co‐intercalation
Na
+
H
2
O
into
van
der
Waals
gaps
a
near‐infrared
Type
I
photosensitizer
periodontitis
treatment.
The
/H
intercalation
can
shorten
its
length,
generate
rich
oxygen
vacancies,
enlarge
interlayer
gaps.
Such
structural
changes
thus
induce
color
change
from
white
to
dark
blue
with
strong
(NIR)
absorption.
When
used
photosensitizer,
I‐MoO
3−
x
exhibit
much
higher
activities
generation
superoxide
radical
(·O
−
)
under
an
808
nm
laser
irradiation
than
that
pristine
nanobelts.
Therefore,
prepared
show
spectral
antibacterial
activity
Escherichia
coli
Saccharomyces
aureus
,
yielding
good
clinical
therapeutic
effect
on
periodontitis.
Our
study
proves
be
simple
but
powerful
strategy
activate
layered
high‐performance
PDT.
Biomaterials Science,
Год журнала:
2023,
Номер
11(12), С. 4226 - 4237
Опубликована: Янв. 1, 2023
A
self-healing
antibacterial
hydrogel
was
fabricated
for
accelerating
infected
wound
healing.
This
possesses
biocompatible,
self-healing,
and
antibiotic-free
properties,
thus
is
promising
as
a
dressing.
ACS Applied Materials & Interfaces,
Год журнала:
2023,
Номер
15(19), С. 22903 - 22914
Опубликована: Март 30, 2023
Conventional
antibiotic-based
treatment
of
bacterial
infections
remains
one
the
most
difficult
challenges
in
medicine
because
threat
multidrug
resistance
caused
by
indiscriminate
abuse.
To
solve
these
problems,
it
is
essential
to
develop
an
effective
antibacterial
agent
that
can
be
used
at
a
small
dose
while
minimizing
occurrence
multiple
resistance.
Metal–organic
frameworks
(MOFs),
which
are
hyper-porous
hybrid
materials
containing
metal
ions
linked
organic
ligands,
have
recently
attracted
attention
their
strong
activity
through
metal-ion
release,
unlike
conventional
antibiotics.
In
this
study,
we
developed
photoactive
MOF-derived
cobalt–silver
bimetallic
nanocomposite
(Ag@CoMOF)
simply
depositing
silver
nanoparticles
on
cobalt-based
MOF
nanoscale
galvanic
replacement.
The
structure
continuously
releases
(i.e.,
Ag
and
Co
ions)
aqueous
phase
exhibits
photothermal
conversion
effect
nanoparticles,
accompanied
rapid
temperature
increase
25–80
°C
under
near-infrared
(NIR)
irradiation.
Using
MOF-based
nanocomposite,
superior
activities
were
achieved
22.1-fold
for
Escherichia
coli
18.3-fold
Bacillus
subtilis
enhanced
inhibition
growth
liquid
culture
environment
compared
with
generally
chemical
addition,
confirmed
synergistic
enhancement
ability
induced
NIR-triggered
heating
membrane
disruption
even
when
using
amount
nanocomposites.
We
envision
novel
nanostructures
will
replace
traditional
antibiotics
circumvent
present
new
approach
antibiotic
development.
