Biosensors,
Год журнала:
2023,
Номер
13(9), С. 848 - 848
Опубликована: Авг. 25, 2023
Cancer
is
a
common
illness
with
high
mortality.
Compared
traditional
technologies,
biomarker
detection,
its
low
cost
and
simple
operation,
has
higher
sensitivity
faster
speed
in
the
early
screening
prognosis
of
cancer.
Therefore,
extensive
research
focused
on
development
biosensors
construction
sensing
interfaces.
Molybdenum
disulfide
(MoS2)
promising
two-dimensional
(2D)
nanomaterial,
whose
unique
adjustable
bandgap
shows
excellent
electronic
optical
properties
biosensor
It
not
only
advantages
catalytic
activity
manufacturing
costs,
but
it
can
also
further
expand
application
hybrid
structures
through
different
functionalization,
widely
used
various
fields.
Herein,
we
provide
detailed
introduction
to
structure
synthesis
methods
MoS2,
explore
advantages/disadvantages
exhibited
by
structures.
Specifically,
focus
performance
MoS2
composite
structures,
discuss
widespread
cancer
biomarkers
detection
from
both
electrochemical
dimensions.
Additionally,
cross
emerging
have
expanded
other
sensors
based
for
diagnosis.
Finally,
summarized
challenges
prospects
synthesis,
functionalization
groups,
applications,
provided
some
insights
into
potential
applications
these
nanomaterials
wider
range
New Journal of Chemistry,
Год журнала:
2024,
Номер
48(23), С. 10628 - 10635
Опубликована: Янв. 1, 2024
In
the
presence
of
H
2
O
,
Au@Ce-MOF@COF-HRP
can
effectively
promote
oxidation
hydroquinone
(HQ)
to
benzoquinone
(BQ),
and
electrochemical
reduction
signal
BQ
was
significantly
amplified.
Heliyon,
Год журнала:
2024,
Номер
10(12), С. e33238 - e33238
Опубликована: Июнь 1, 2024
Objective
and
rationaleThis
study
aimed
to
develop
a
highly
sensitive
selective
single-stranded
DNA
(ssDNA)
aptamer
targeting
cardiac
troponin
I
(cTnI),
crucial
biomarker
for
acute
myocardial
infarction
(AMI).
The
objective
was
fabricate
novel
electrochemical
sensor
using
composite
material
of
cobalt-nickel
metal-organic
framework
(CoNi-MOF)
on
screen-printed
carbon
electrodes
(SPCE),
leveraging
the
composite's
large
surface
area
excellent
electrical
conductivity
alongside
aptamer's
high
affinity
cTnI.MethodsThe
fabricated
CoNi-MOF
SPCE
characterized
its
properties.
They
conducted
measurements
assess
sensor's
performance
in
detecting
cTnI.
stability,
reproducibility,
electro-catalytic
activity
were
evaluated.ResultsThe
demonstrated
linear
detection
cTnI
over
concentration
range
5–75
pg/mL,
with
low
limit
(LOD)
13.2
pM.
Remarkable
stability
reproducibility
observed
detection.
exhibited
exceptional
activity,
enabling
accurate
quantification
levels
various
solutions.ConclusionsThis
research
presents
significant
advancement
towards
development
reliable,
cost-effective,
easily
deployable
sensors
clinical
applications.
versatility
across
different
ranges
highlights
potential
utility
diverse
settings,
particularly
early
monitoring
conditions.
International Journal of Electrochemical Science,
Год журнала:
2024,
Номер
19(4), С. 100537 - 100537
Опубликована: Март 6, 2024
Enrofloxacin
(ENR)
is
widely
applied
in
preventing
and
treating
animal
diseases
hence
directly
passed
into
animal-derived
foods.
Therefore,
the
detection
of
this
drug
food
samples
must
be
strengthened
to
ensure
safety.
In
work,
a
simple,
sensitive
electrochemical
aptasensor
for
ENR
was
fabricated
by
using
magnetic
nanoparticles
(MNPs)
as
carriers.
The
aptamer
modified
on
surface
MNPs
capture
target
or
biotin-complementary
strand
then
recognize
streptavidin-horse
radish
peroxidase.
Subsequently,
resulting
were
easily
transferred
onto
glassy
carbon
electrode
with
help
its
integral
magnet.
Under
optimal
experimental
conditions,
linear
relationship
between
variable
LSV
current
logarithm
concentration
range
0.01–100
ng/mL
obtained
limit
at
4.9
pg/mL.
addition,
method
exhibited
good
stability,
selectivity,
reproducibility
successfully
detecting
spiked
chicken
recoveries
100.70%–108.96%.
proposed
easy
fabricate
process;
it
particularly
suitable
sample
pretreatment
beneficial
removing
interference
complex
matrix.
Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Tetracyclines
(TCs)
are
widely
present
in
the
environment
with
extreme
toxicity,
low
concentrations,
coexistence
a
variety
of
pollutants,
and
similarity
their
individual
molecular
structures
toxicology.
These
challenges
make
it
difficult
to
analyze
monitor
TCs
as
class
molecules
simultaneously.
In
this
study,
broad-spectrum
aptamer
capable
recognizing
was
developed
by
artificially
editing
single-specific
aptamer.
Subsequently,
based
on
mathematical
proof
detection
TCs,
an
electrochemical
sensor
constructed
enable
simple
rapid
monitoring
high
sensitivity,
selectivity,
wide
range.
The
exhibits
range
0.01
1000
nM
limit
1.18
pM,
while
maintaining
excellent
selectivity
even
presence
interfering
substances
at
concentrations
up
100
times
test
concentration.
This
is
suitable
for
quantifying
overall
level
various
environmental
scenarios,
facilitating
study
transport
transformation
processes
systems.
Finally,
recognition
mechanism
elucidated,
which
makes
method
rational
universal,
will
help
future
researchers
obtain
aptamers
analysis
multiple
classes
pollutants.
Dalton Transactions,
Год журнала:
2023,
Номер
52(33), С. 11552 - 11557
Опубликована: Янв. 1, 2023
Functional
materials
are
considered
one
of
the
most
critical
factors
in
constructing
high-performance
electrochemical
aptasensors
sensing
field.
In
this
work,
microporous
Zr-MOF
UiO-66
(UiO
=
Universitetet
i
Oslo)
is
selected
for
assembly
with
carbon
nanotubes
(CNTs)
to
prepare
a
CNT@UiO-66
composite.
The
as-synthesized
composite
has
high
surface
area,
excellent
stability,
good
electrical
conductivity,
and
abundant
Zr(IV)
sites,
conferring
it
great
potential
application
fabricating
aptasensors.
It
gratifying
that
impedimetric
aptasensor
can
detect
trace
oxytetracycline
(OTC)
from
0.01
0.7
pg
mL-1
low
limit
detection
(LOD)
1.48
fg
mL-1.
Meanwhile,
fabricated
sensor
based
on
fine
selectivity,
available
reproducibility.
particular,
CNT@UiO-66-based
quantitatively
OTC
concentration
real
samples.
