Navigating confinement: Mechanotransduction and metabolic adaptation DOI
Alice Amitrano, Debanik Choudhury, Κωνσταντίνος Κωνσταντόπουλος

и другие.

Current Opinion in Cell Biology, Год журнала: 2025, Номер 94, С. 102487 - 102487

Опубликована: Фев. 24, 2025

Язык: Английский

The Emerging Role of Ferroptosis in EBV-Associated Cancer: Implications for Cancer Therapy DOI Creative Commons
Shan He, Cheng Luo, Feng Shi

и другие.

Biology, Год журнала: 2024, Номер 13(7), С. 543 - 543

Опубликована: Июль 18, 2024

Ferroptosis is a novel and iron-dependent form of programmed cell death, which has been implicated in the pathogenesis various human cancers. EBV well-recognized oncogenic virus that controls multiple signaling pathways within host cell, including ferroptosis signaling. Recent studies show inducing could be an efficient therapeutic strategy for EBV-associated tumors. This review will firstly describe mechanism ferroptosis, then summarize infection tumors, as well crosstalk between pathway, finally discuss role potential application ferroptosis-related reagents

Язык: Английский

Процитировано

4
AKR1B1-dependent fructose metabolism enhances malignancy of cancer cells DOI Creative Commons
Qing Zhao, Bing Han, Lu Wang

и другие.

Cell Death and Differentiation, Год журнала: 2024, Номер 31(12), С. 1611 - 1624

Опубликована: Окт. 15, 2024

Abstract Fructose metabolism has emerged as a significant contributor to cancer cell proliferation, yet the underlying mechanisms and sources of fructose for cells remain incompletely understood. In this study, we demonstrate that can convert glucose into through process called AKR1B1 -mediated polyol pathway. Inhibiting endogenous production deletion dramatically suppressed glycolysis, resulting in reduced migration, inhibited growth, induction apoptosis cycle arrest. Conversely, acceleration overexpression been shown significantly enhance proliferation migration with increased S progression. Our findings highlight crucial role malignancy support need further investigation potential therapeutic target.

Язык: Английский

Процитировано

3
An alginate-cellulose based bioink mimics the viscoelastic features of the melanoma microenvironment and its influence on cell cycle and invasion DOI Creative Commons

C. F. Eckert,

Steven K. Schmidt, Jessica Faber

и другие.

Bioprinting, Год журнала: 2025, Номер unknown, С. e00384 - e00384

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Targeted Delivery of SmacN7 Peptide Induces Immunogenic Cell Death in Cervical Cancer Treatment DOI
Yan Dai, Shentao Lu,

Linna Wei

и другие.

Applied Biochemistry and Biotechnology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 25, 2025

Язык: Английский

Процитировано

0
Navigating confinement: Mechanotransduction and metabolic adaptation DOI
Alice Amitrano, Debanik Choudhury, Κωνσταντίνος Κωνσταντόπουλος

и другие.

Current Opinion in Cell Biology, Год журнала: 2025, Номер 94, С. 102487 - 102487

Опубликована: Фев. 24, 2025

Язык: Английский

Процитировано

0