Asian Journal of Organic Chemistry,
Год журнала:
2023,
Номер
12(7)
Опубликована: Май 23, 2023
Abstract
The
Povarov
reaction
is
a
representative
multicomponent
used
for
synthesizing
nitrogen‐containing
aromatic
compounds
from
amines,
aldehydes,
and
dienophiles,
such
as
electron‐rich
alkenes
alkynes.
In
this
study,
we
investigated
triple
of
1,3,5‐triaminobenzne
with
aldehydes
phenylacetylene
to
obtain
triazatriphenylene
derivatives.
Reactions
arylaldehydes
containing
electron‐donating
groups
proceeded
smoothly
provide
contrast,
reactions
electron‐withdrawing
resulted
in
low
yields.
are
probably
more
favorable
terms
high
stability
imine
intermediates
smooth
electrophilic
cyclization.
Single‐crystal
X‐ray
structure
analysis
revealed
that
the
aryl
derived
had
small
dihedral
angles
between
core.
derivative
tertiary
butyl
(
tBu‐TaT
)
glass
transition
temperature,
while
without
H‐TaT
lower
highest
occupied
molecular
orbital
(HOMO)
lowest
unoccupied
(LUMO)
level
served
an
efficient
hole‐blocking
material
better
electron
transport
properties
than
those
.
This
study
provides
insights
into
scope
limitations
based
on
reaction,
substituent
dependence
crystal
structures,
physical
π‐extended
compounds.
Organic & Biomolecular Chemistry,
Год журнала:
2022,
Номер
20(12), С. 2356 - 2369
Опубликована: Янв. 1, 2022
Enaminones
and
analogous
stable
enamines
are
well
known
as
platform
building
blocks
in
organic
synthesis
for
the
construction
of
heterocyclic
compounds,
especially
N-heterocycles.
To
date,
enaminones
have
been
successfully
employed
various
5-
or
6-
membered
heterocycles.
Recently,
synthetic
protocols
accomplished
by
diversity-oriented
annulation
reactions
based
on
C-N
bond
cleavage
gained
notable
success.
In
this
review,
development
transition
metal-free
product
featuring
a
is
reviewed.
Asian Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 1, 2025
Abstract
In
this
study
we
introduce
indoline
hemiaminals
as
phenacyl
bromide
surrogates
for
the
synthesis
of
deaminokynurenine
derivatives
through
cyclic‐linear
tautomeric
intermediates.
The
reaction
proceeds
a
tandem
process
involving
ring
opening
hemiaminals,
generating
transient
acyclic
aldehydes
which
are
then
trapped
with
in
situ
generated
enolate
species.
Our
protocol
overcomes
traditional
dilemma
production
polar‐mismatch
1,4‐dicarbonyl
compounds
by
utilizing
highly
electrophilic
linear
aldehyde
and
late‐stage
transposition
carbonyl
moiety.
synthetic
utility
our
transformation
was
demonstrated
follow‐up
transformations,
including
first
total
quinoline‐2,4‐dione
alkaloid.
New Journal of Chemistry,
Год журнала:
2023,
Номер
47(13), С. 6102 - 6113
Опубликована: Янв. 1, 2023
Hantzsch
pyridine
ester
has
been
used
as
a
precursor
for
the
synthesis
of
dihydrazone
ligands.
Two
dinuclear
V(
v
)
complexes
obtained
by
these
ligands
show
high
catalytic
activity
in
oxidation
sulfides.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(21), С. 15350 - 15357
Опубликована: Окт. 23, 2023
A
palladium-catalyzed
oxidative
amination
of
inactive
olefins
with
an
aromatic
amine
was
developed
using
a
copper
acetate
oxidant
to
yield
corresponding
secondary
and
tertiary
enamines
in
moderate
good
yields.
This
new
procedure
outlines
efficient
approach
for
the
construction
enamine
skeletons.
European Journal of Organic Chemistry,
Год журнала:
2022,
Номер
2022(30)
Опубликована: Май 11, 2022
Abstract
In
the
current
Perspective
article,
we
critically
review
and
discuss
importance
of
solvent
effects
on
multicomponent
reactions,
likely
most
neglected
aspect
in
this
research
field.
Although
solvent‐free
reactions
may
be
desirable
sometimes,
still
require
a
to
properly
promote
them.
This
requirement
makes
knowledge
all
drawbacks
advantages
each
central
issue
when
trying
optimize
reactions.
Yet,
only
few
studies
with
actual
evidence
these
key
have
been
published.
For
quantitative
solvents,
are
even
scarcer.
Perspective,
argue
that
greater
efforts
should
directed
such
fundamental
studies.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
89(1), С. 111 - 123
Опубликована: Дек. 9, 2023
The
chiral
framework
based
on
11-aminomefloquine
has
been
utilized
for
the
first
time
to
construct
bifunctional
organocatalysts.
These
catalysts
demonstrate
high
enantioselectivity
in
both
Michael
additions
and
Friedel-Crafts
reactions
across
a
variety
of
substrates,
achieving
up
>99%
ee.
distinctive
feature
is
incorporation
secondary
amine
group,
offering
unique
tight
hydrogen-bonding
capabilities
protonated
state,
as
supported
by
DFT
computation.
diversity
these
organocatalysts
suggests
their
broad
applicability
multiple
reaction
classes.
International Journal of Corrosion,
Год журнала:
2022,
Номер
2022, С. 1 - 15
Опубликована: Май 27, 2022
Four
enaminoesters
derived
from
halogenated
aniline,
with
potential
anticorrosion
activity,
were
synthesized
and
tested
against
carbon
steel
AISI
1020
in
acid
medium
using
1.0
mol
L-1
HCl.
The
synthesis
was
demonstrated
through
the
reaction
of
ethyl
acetoacetate
four
different
amines,
presence
glacial
acetic
molecular
sieve,
ethanol
as
solvent
for
24
h.
evaluation
anticorrosive
activity
performed
gravimetric
technique
electrochemical
methods,
such
impedance
spectroscopy
(EIS),
linear
polarization
resistance
(LPR),
potentiodynamic
(PP).
Results
indicated
that
F-EN
(Ethyl
(2Z)-3-[(4-fluoro-phenyl)-amino]-but-2-enoate)
inhibitor
had
higher
corrosion
inhibition
efficiency,
98%
by
mass
loss,
85%
techniques.
Adsorption
obeyed
Langmuir
isotherm,
thus
suggesting
inhibitors
form
a
monolayer
film
metal
surface.
These
results
also
contributed
to
calculations
physicochemical
parameters
Ea
,
△H≠ads△S≠ads
which
confirmed
when
compared
absence
inhibitors.
Applied Organometallic Chemistry,
Год журнала:
2022,
Номер
37(1)
Опубликована: Окт. 19, 2022
An
efficient
acid‐catalyzed
synthesis
of
1,5‐diaryl‐3‐(arylamino)‐1
H
‐pyrrol‐2(5
)‐ones
is
reported
using
novel
N
‐sulfonic
acid
modified
poly
(styrene‐diethylenetriamine)
through
three‐component
reaction
between
aldehyde,
amine,
and
ethyl
pyruvate
in
high
yields
short
times.
This
heterogeneous
solid
catalyst
produced
by
reacting
amine‐modified
chloromethyl
polystyrene
with
neat
chlorosulfonic
acid.
The
structure
the
synthesized
was
examined
Fourier
transform‐infrared
spectroscopy
(FT‐IR),
X‐ray
diffraction
(XRD),
dynamic
light
scattering
(DLS),
thermogravimetric
analysis
(TGA),
differential
thermal
(DTA),
scanning
electron
micrograph
(SEM),
Brunauer–Emmett–Teller
(BET),
energy
dispersive
(EDS),
elemental
analyses.
has
many
advantages,
including
an
easy
work‐up
procedure,
a
product
yield,
capability
to
be
easily
regenerated
reused
for
at
least
five
cycles
without
losing
its
activity.
