Eye-movement replay supports episodic remembering

Proceedings of the Royal Society B Biological Sciences, Год журнала: 2022, Номер 289(1977)

Опубликована: Июнь 15, 2022

When we bring to mind something have seen before, our eyes spontaneously unfold in a sequential pattern strikingly similar that made during the original encounter, even absence of supporting visual input. Oculomotor movements eye may then serve opposite purpose acquiring new information; they as self-generated cues, pointing stored memories. Over 50 years ago Donald Hebb, forefather cognitive neuroscience, posited such replay supports ability mentally recreate visuospatial relations episodic remembering. However, direct evidence for this influential claim is lacking. Here isolate properties spontaneous encoding and retrieval pure recall memory task capture their encoding-retrieval overlap. Critically, show fidelity with which series consecutive from initial sequentially retained subsequent predicts quality recalled memory. Our findings provide scanpaths are replayed assemble reconstruct spatio-temporal remember further suggest distinct scanpath differentially contribute depending on nature goal-relevant

Язык: Английский

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Saccades are locked to the phase of alpha oscillations during natural reading

PLoS Biology, Год журнала: 2023, Номер 21(1), С. e3001968 - e3001968

Опубликована: Янв. 17, 2023

We saccade 3 to 5 times per second when reading. However, little is known about the neuronal mechanisms coordinating oculomotor and visual systems during such rapid processing. Here, we ask if brain oscillations play a role in temporal coordination of visuomotor integration. simultaneously acquired MEG eye-tracking data while participants read sentences silently. Every sentence was embedded with target word either high or low lexical frequency. Our key finding demonstrated that onsets were locked phase alpha (8 13 Hz), particular, for saccades towards frequency words. Source modelling which locked, generated right-visual motor cortex (BA 7). findings suggest serve time processing between natural reading, this becomes more pronounced demanding

Язык: Английский

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Entorhinal grid-like codes and time-locked network dynamics track others navigating through space

Nature Communications, Год журнала: 2023, Номер 14(1)

Опубликована: Янв. 31, 2023

Abstract Navigating through crowded, dynamically changing environments requires the ability to keep track of other individuals. Grid cells in entorhinal cortex are a central component self-related navigation but whether they also others’ movement is unclear. Here, we propose that grid-like codes make an essential contribution socio-spatial navigation. Sixty human participants underwent functional magnetic resonance imaging (fMRI) while observing and re-tracing different paths demonstrator navigated virtual reality environment. Results revealed tracked individual navigating space. The activity was time-locked increases co-activation entorhinal-cortical connectivity included striatum, hippocampus, parahippocampal right posterior parietal cortices. Surprisingly, grid-related effects during observation were stronger worse performed when subsequently demonstrator’s paths. Our findings suggests network dynamics grid-cell-related might serve distribute information about location others throughout brain.

Язык: Английский

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Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease

Alzheimer s & Dementia, Год журнала: 2023, Номер 20(1), С. 301 - 315

Опубликована: Авг. 23, 2023

Abstract INTRODUCTION Memory‐associated neural circuits produce oscillatory events including theta bursts (TBs), sleep spindles (SPs), and slow waves (SWs) in electroencephalography (EEG). Changes the “coupling” of these may indicate early Alzheimer's disease (AD) pathogenesis. METHODS We analyzed 205 aging adults using single‐channel EEG, cerebrospinal fluid (CSF) AD biomarkers, Clinical Dementia Rating® (CDR®) scale. mapped SW‐TB SW‐SP circuit coupling precision to amyloid positivity, cognitive impairment, CSF biomarkers. RESULTS Cognitive impairment correlated with lower TB spectral power coupling. Cognitively unimpaired, positive individuals demonstrated compared negative individuals. Significant biomarker correlations were found event Aβ 42 /Aβ 40 , phosphorylated‐ tau 181 total‐tau. DISCUSSION Sleep‐dependent memory processing integrity can be measured for both This breakdown associates increased pathology, impairment. Highlights At‐home EEG is a potential linked memory. Circuit associated positivity asymptomatic adults. Levels also correlate EEG. Theta burst decreased very mild technique enable inexpensive wearable EEGs monitoring brain health.

Язык: Английский

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Memory and consciousness

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 553 - 569

Опубликована: Март 18, 2024

Язык: Английский

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Overlapping and distinct phenotypic profiles in Alzheimer’s disease and late onset epilepsy: a biologically-based approach

Frontiers in Neurology, Год журнала: 2024, Номер 14

Опубликована: Март 13, 2024

Due to shared hippocampal dysfunction, patients with Alzheimer’s dementia and late-onset epilepsy (LOE) report memory decline. Multiple studies have described the epidemiological, pathological, neurophysiological, behavioral overlap between Disease LOE, implying a bi-directional relationship. We describe neurobiological decline occurring at different spatial in AD LOE patients, which may explain why their phenotypes differ. provide suggestions for clinical recognition of dual presentation novel approaches testing that reflect an “inside-out,” or biologically-based approach memory. New language assessments could detect—and treat—memory impairment earlier, actionable stage.

Язык: Английский

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Gaze dynamics during natural scene memorization and recognition

Cognition, Год журнала: 2025, Номер 259, С. 106098 - 106098

Опубликована: Март 6, 2025

Язык: Английский

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Refixation behavior in naturalistic viewing: Methods, mechanisms, and neural correlates

Attention Perception & Psychophysics, Год журнала: 2024, Номер unknown

Опубликована: Янв. 2, 2024

Abstract When freely viewing a scene, the eyes often return to previously visited locations. By tracking eye movements and coregistering EEG, such refixations are shown have multiple roles: repairing insufficient encoding from precursor fixations, supporting ongoing by resampling relevant locations prioritized aiding construction of memory representations. All these functions refixation behavior understood be underpinned three oculomotor cognitive systems their associated brain structures. First, immediate saccade planning prior involves attentional selection candidate revisit. This process is likely supported dorsal network. Second, visual working memory, involved in maintaining task-related information, cortex. Third, higher-order relevance scene locations, which depends on general knowledge understanding meaning, hippocampal system. Working together, structures bring about that balances exploring unvisited areas with exploiting through refixations.

Язык: Английский

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Autobiographical Implicit Association Test and eye movements: fixations topography enables detection of autobiographical memories

Frontiers in Psychology, Год журнала: 2024, Номер 15

Опубликована: Янв. 29, 2024

Introduction Autobiographical memory is the capacity to recollect memories of personally experienced events. The detection such plays a key role in criminal trials. Among behavioral memory-detection methods, autobiographical Implicit Association Test (aIAT) has gained popularity for its flexibility and suitability forensic applications. aIAT reaction time-based methodology aiming assess whether information about an event encoded respondent’s mind. Here, we introduced eye-D index, measure based on topography fixations while performing aIAT, as additional detect covertly. Methods In this study, participants were involved mock-crime experiment which they could act Guilty or Innocent. One week later all underwent combined with eye-tracking investigate presence crime-related memory. Results showed higher number towards category labels block true sentences shared same response sentences, compared paired describing alternative version. Innocent opposite pattern. This unbalanced allocation attention was quantified by index found be highly correlated standard aIAT-D index. Discussion suggests that more indicate increased cognitive load monitoring conflicts. These preliminary results highlight tool covertly aIAT.

Язык: Английский

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Investigating the suitability of online eye tracking for psychological research: Evidence from comparisons with in-person data using emotion–attention interaction tasks

Behavior Research Methods, Год журнала: 2023, Номер 56(3), С. 2213 - 2226

Опубликована: Июнь 20, 2023

Язык: Английский

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