The coral microbiome in sickness, in health and in a changing world

Nature Reviews Microbiology, Год журнала: 2024, Номер 22(8), С. 460 - 475

Опубликована: Март 4, 2024

Язык: Английский

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Probiotics reshape the coral microbiome in situ without detectable off-target effects in the surrounding environment

Communications Biology, Год журнала: 2024, Номер 7(1)

Опубликована: Апрель 9, 2024

Beneficial microorganisms for corals (BMCs), or probiotics, can enhance coral resilience against stressors in laboratory trials. However, the ability of probiotics to restructure microbiome situ is yet be determined. As a first step elucidate this, we inoculated putative probiotic bacteria (pBMCs) on healthy colonies Pocillopora verrucosa Red Sea, three times per week, during 3 months. pBMCs significantly influenced microbiome, while surrounding seawater and sediment remained unchanged. The genera Halomonas, Pseudoalteromonas, Bacillus were enriched probiotic-treated corals. Furthermore, treatment also correlated with an increase other beneficial groups (e.g., Ruegeria Limosilactobacillus), decrease potential pathogens, such as Vibrio. all (treated non-treated) throughout experiment, could not track health improvements protection stress. Our data indicate that healthy, therefore stable, microbiomes restructured situ, although repeated continuous inoculations may required these cases. Further, our study provides supporting evidence that, at studied scale, have no detectable off-target effects near

Язык: Английский

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Microbial-Based Therapies to Restore and Rehabilitate Disrupted Coral Health

Coral reefs of the world, Год журнала: 2025, Номер unknown, С. 181 - 195

Опубликована: Янв. 1, 2025

Язык: Английский

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Integrating microbiome science and evolutionary medicine into animal health and conservation

Biological reviews/Biological reviews of the Cambridge Philosophical Society, Год журнала: 2023, Номер 99(2), С. 458 - 477

Опубликована: Ноя. 13, 2023

ABSTRACT Microbiome science has provided groundbreaking insights into human and animal health. Similarly, evolutionary medicine – the incorporation of eco‐evolutionary concepts primarily medical theory practice is increasingly recognised for its novel perspectives on modern diseases. Studies host–microbe relationships have been expanded beyond humans to include a wide range taxa, adding new facets our understanding ecology, evolution, behaviour, In this review, we propose that broader application medicine, combined with microbiome science, can provide valuable innovative care conservation. First, draw classic ecological principles, such as alternative stable states, an framework variation in microbiomes their role health wellbeing. With focus mammalian gut microbiomes, apply populations animals under care, particular relevance many species suffer diseases linked microbial dysfunction (e.g. distress infection, autoimmune disorders, obesity). We discuss diet landscapes (i.e. microbes animal's external environment), two factors are ( i ) proposed represent mismatches captive animals, ii structure function, iii potentially best understood from perspective. Keeping within framework, highlight potential benefits pitfalls therapies, pre‐ probiotics, faecal microbiota transplants, rewilding. limited, yet growing, empirical evidence use therapies modulate beneficially. Interspersed throughout, 12 actionable steps, grounded be applied practical management. encourage these steps paired integration definitions appropriate standards. The herein may appreciated when broad diversity rather than solely focused humans. urge professionals, veterinarians, nutritionists, scientists, others collaborate efforts, allowing simultaneous patients generation data.

Язык: Английский

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A coral-associated actinobacterium mitigates coral bleaching under heat stress

Environmental Microbiome, Год журнала: 2023, Номер 18(1)

Опубликована: Ноя. 23, 2023

The positive effects of exposing corals to microorganisms have been reported though how the benefits are conferred poorly understood. Here, we isolated an actinobacterial strain (SCSIO 13291) from Pocillopora damicornis with capabilities synthesize antioxidants, vitamins, and antibacterial antiviral compounds supported phenotypic and/or genomic evidence. Strain SCSIO 13291 was labeled 5 (and - 6)-carboxytetramethylrhodamine, succinimidyl ester cell suspension directly inoculated onto coral polyp tissues when nubbins were under thermal stress in a mesocosm experiment. We then visualized labelled bacterial cells analyzed physiological, transcriptome microbiome elucidate effect this on holobiont stress.Subsequent microscopic observations confirmed presence bacterium attached polyps. Addition reduced signs bleaching subjected heat stress. At same time, alterations gene expression, which involved reactive oxygen species light damage mitigation, attenuated apoptosis exocytosis addition metabolite utilization, observed host Symbiodiniaceae populations. In addition, associated community altered more stable ecological network for samples strain.Our results provide insights into putative probiotic that mitigate signs. This study suggests inoculation bacteria can potentially benefit through conferring metabolic activities or indirect mechanisms suppling additional nutrient sources.

Язык: Английский

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Feeding Drosophila gut microbiomes from young and old flies modifies the microbiome

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Апрель 2, 2024

Abstract It is becoming increasingly evident that the myriad of microbes in gut, within cells and attached to body parts (or roots plants), play crucial roles for host. Although this has been known decades, recent developments molecular biology allow expanded insight into abundance function these microbes. Here we used vinegar fly, Drosophila melanogaster , investigate fitness measures across lifetime flies fed a suspension gut harvested from young or old flies, respectively. Our hypothesis was constitutively enriched with ‘Young microbiome’ would live longer be more agile at age (i.e. have increased healthspan) compared an ‘Old microbiome’. Three major take home messages came out our study: (1) microbiomes differ markedly; (2) feeding Young Old altered microbiome recipient (3) two different microbial diets did not any effect on locomotor activity nor lifespan contradicting working hypothesis. Combined, results provide novel interplay between hosts their clearly highlight phenotypic effects transplants probiotics can complex unpredictable.

Язык: Английский

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Localization and symbiotic status of probiotics in the coral holobiont

mSystems, Год журнала: 2024, Номер 9(5)

Опубликована: Апрель 12, 2024

ABSTRACT Corals establish symbiotic relationships with microorganisms, especially endosymbiotic photosynthetic algae. Although other microbes have been commonly detected in coral tissues, their identity and beneficial functions for host are unclear. Here, we confirm the outcomes of inoculation bacteria selected as probiotics use fluorescence situ hybridization (FISH) to define localization Pocillopora damicornis . Our results show first evidence inherent presence Halomonas sp. Cobetia native even before inoculation. Furthermore, relative enrichment these tissue-associated through corals correlates health improvements, such increases potential, productivity. study suggests status by indicating within gastrodermis epidermis correlating increased abundance active holobiont. This knowledge is crucial facilitate screening application that may not be transient members microbiome. IMPORTANCE Despite promising associated some scarce regarding bacterial cells found tissue, correlation between two aspects still missing. gap limits our understanding actual diversity coral-associated whether symbionts beneficial. Some researchers, example, suggesting probiotic should only focus on very few known bacteria, Endozoicomonas sp., assuming currently tested tissue-associated. provide specific FISH probes expand probiotics. The microorganisms (BMCs) inside tissues gastric cavities also supports notion direct interactions underpin role. a new breakthrough; argue against possibility positive effects BMCs due factors related interaction, simply feeds inoculated or change water quality.

Язык: Английский

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Soil microbiome interventions for carbon sequestration and climate mitigation

mSystems, Год журнала: 2024, Номер unknown

Опубликована: Дек. 18, 2024

Mitigating climate change in soil ecosystems involves complex plant and microbial processes regulating carbon pools flows. Here, we advocate for the use of microbiome interventions to help increase stocks curb greenhouse gas emissions from managed soils. Direct include introduction strains, consortia, phage, transplants, whereas indirect managing conditions or additives modulate community composition its activities. Approaches using microbially catalyzed increasing inputs plants, promoting organic matter (SOM) formation, reducing SOM turnover production diverse gases. Marginal degraded soils may provide greatest opportunities enhancing global stocks. Among many knowledge gaps this field, crucial influencing transformation plant-derived into identity microbes activities impacting transformation. As a critical step forward, encourage broadening current widespread screening potentially beneficial microorganisms encompass functions relevant stimulating Moreover, developing these interventions, must consider potential ecological ramifications uncertainties, such as incurred by homogenous inoculants need site-specificity given extreme variation among habitats. Incentivization implementation at large spatial scales could effectively harness increases stocks, helping mitigate impacts change.

Язык: Английский

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When Microbial Interactions Go Wrong: Coral Bleaching, Disease, and Dysbiosis

Coral reefs of the world, Год журнала: 2025, Номер unknown, С. 169 - 180

Опубликована: Янв. 1, 2025

Язык: Английский

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Complexity of the Coral Microbiome Assembly

Coral reefs of the world, Год журнала: 2025, Номер unknown, С. 105 - 110

Опубликована: Янв. 1, 2025

Язык: Английский

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