BMC Psychiatry, Год журнала: 2024, Номер 24(1)
Опубликована: Дек. 18, 2024
Язык: Английский
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown
Опубликована: Фев. 25, 2025
Functional magnetic resonance imaging (fMRI) in awake infants has the potential to reveal how early developing brain gives rise cognition and behavior. However, infant fMRI poses significant methodological challenges that have hampered wider adoption. The present work takes stock after collection of a substantial amount data across multiple studies from two labs at different institutions. We leveraged these glean insights on participant recruitment, experimental design, acquisition could be useful consider for future studies. Across 766 sessions, we explored factors influenced much usable were obtained per session (average 9 minutes). age an predicted whether they would successfully enter scanner (younger was more likely) and, if did enter, number minutes functional retained preprocessing. also by assigned sex (female more), paradigm (movies better than blocks events), stimulus content (social abstract). In addition, assessed value attempting collect experiments session, approach yielded one experiment averaging all sessions (including those with no data). Although any given scan is unpredictable, findings support feasibility suggest practices optimize research.
Язык: Английский
Процитировано
1
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown
Опубликована: Апрель 21, 2025
Abstract Cortical folding begins in utero as sulci emerge and continues postnatally deepen. However, the timeline mechanisms underlying postnatal sulcal development remain unknown. Using structural quantitative magnetic resonance imaging infants from birth to one year of age, we longitudinally measured macroanatomical microstructural major that between 16th 31st gestational weeks. We find earlier are deeper at deepen a slower rate than later emerging sulci. Sulci also become wider, thicker, microstructurally denser, while their curvature decreases. Notably, mean depth is predicted by weighted sum span, thickness, curvature, tissue microstructure, with differential weights across Analysis local along sulcus reveals portions (fundi) have higher density surrounding walls. These data reveal deepening nonuniform depends on time emergence utero, multiple factors. Together, these findings important ramifications for theories cortical elucidating neurodevelopmental disorders delays.
Язык: Английский
Процитировано
0
Journal of Neuroscience, Год журнала: 2024, Номер 44(40), С. e1291242024 - e1291242024
Опубликована: Окт. 2, 2024
Most studies on the development of visual system have focused mechanisms shaping early stages up to level primary cortex (V1). Much less is known about after V1 that handle higher functions fundamental everyday life. The standard model for maturation these areas it occurs sequentially, according positions in adult hierarchy. Yet, existing literature reviewed here paints a different picture, one which configuration emerges through sequence unique network configurations are not mere partial versions In addition studying per se fill major gaps knowledge, will be crucial adopt network-level perspective future investigations unravel normal developmental mechanisms, identify vulnerabilities disorders, and eventually devise treatments disorders.
Язык: Английский
Процитировано
2
Neurophotonics, Год журнала: 2024, Номер 11(04)
Опубликована: Окт. 8, 2024
The advances and miniaturization in functional near-infrared spectroscopy (fNIRS) instrumentation offer the potential to move classical laboratory-based cognitive neuroscience investigations into more naturalistic settings. Wearable mobile fNIRS devices also provide a novel child-friendly means image brain activity freely moving toddlers preschoolers. Measuring ecologically valid settings with presents additional challenges, such as increased impact of physiological interferences. One most popular methods for minimizing interferences is regress out short separation channels from long [i.e., superficial signal regression (SSR)]. Although this has been extensively investigated adults, little known about systemic changes on signals recorded children either or experiments.
Язык: Английский
Процитировано
1
Опубликована: Май 16, 2024
Over the past several decades, behavioral methods suitable for use with human infants have revealed detailed characteristics of perceptual development, but causal mechanisms that drive these changes remain elusive. Neuroimaging hold promise clarifying by reducing hypothesis space theories how biological and experiential factors interact as abilities emerge become refined during early development. Here we review milestones in key areas development infancy childhood, summarize potential value-added neural measures, highlight new analytic techniques can further clarify future. We also outline patterns interaction describe findings change age raise some cautionary notes about to interpret interactions.
Язык: Английский
Процитировано
0
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown
Опубликована: Июнь 3, 2024
Abstract Significance The advances and the miniaturization in functional Near Infrared Spectroscopy (fNIRS) instrumentation offers potential to move classical laboratory-based cognitive neuroscience investigations into more naturalistic settings. Wearable mobile fNIRS devices also provide a novel child-friendly means image brain activity freely moving toddlers preschoolers. Measuring ecologically valid settings with presents additional challenges, such as increased impact of physiological interferences. One most popular methods minimize interferences is regress out short separation channels from long (i.e., superficial signal regression or SSR). Whilst this has been extensively investigated adults, little known about systemic changes on signals recorded children either experiments. Aim We aim investigate if extracerebral occur preschoolers, whether SSR can help these Approach collected data 3-to-7 years olds during conventional computerized static task dynamic an immersive virtual reality (VR) continuous automatic environment (CAVE). Results Our results show that contamination present both young adults. Importantly, we find helps improving localization activity, and, larger extent, VR task. Conclusions Following results, formulate suggestions advance field developmental neuroimaging fNIRS, particularly ecological
Язык: Английский
Процитировано
0
bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown
Опубликована: Окт. 16, 2024
Abstract By adulthood, humans rapidly identify objects from sparse visual displays and across significant disruptions to their appearance. What are the minimal conditions needed achieve robust recognition abilities when might these develop? To answer questions, we investigated upper-limits of children’s object abilities. We found that children as young 3 years successfully identified at speeds 100 ms (both forward backward masked) under disrupted viewing conditions. contrast, a range computational models implemented with biologically informed properties or optimized for did not reach child-level performance. Models only matched if they received more examples than capable experiencing. These findings highlight robustness human system in absence extensive experience important developmental constraints building plausible machines. Teaser The preschool rival those state-of-the-art artificial intelligence models.
Язык: Английский
Процитировано
0
Religions, Год журнала: 2024, Номер 15(12), С. 1454 - 1454
Опубликована: Ноя. 29, 2024
How do infants praise the Lord? While we cannot say definitively how this is so, exploring idea—particularly in context of intergenerational worship and formation—offers rich theological insights. Scripture declares, “Out mouth babes nursing infants, you have perfected praise” (Matthew 21:16; Psalm 8:2, NKJV), suggesting that (1) indeed God, (2) their by Him. Rather than dismissing as purely metaphorical, article draws on St. Augustine’s concept jubilus, a song with no intelligible words, to explore infants’ babbling might be seen form worship, what learn from it if thus seen. The concludes demonstrating reflection challenge us reevaluate enrich our approaches Contemporary Praise & Worship formation.
Язык: Английский
Процитировано
0
BMC Psychiatry, Год журнала: 2024, Номер 24(1)
Опубликована: Дек. 18, 2024
Язык: Английский
Процитировано
0