Night eating in timing, frequency, and food quality and risks of all-cause, cancer, and diabetes mortality: findings from national health and nutrition examination survey
Nutrition and Diabetes,
Год журнала:
2024,
Номер
14(1)
Опубликована: Фев. 27, 2024
Abstract
Objective
To
investigate
the
association
of
timing,
frequency,
and
food
quality
night
eating
with
all-cause,
cancer,
diabetes
mortality.
Methods
This
study
included
41,744
participants
from
US
National
Health
Nutrition
Examination
Survey
(2002–2018).
Night
information
was
collected
by
24-h
dietary
recall
exposures
were
eating.
Food
assessed
latent
class
analysis.
The
outcomes
mortality,
which
identified
Death
Index
International
Classification
Diseases
10th
Revision.
Adjusted
hazard
ratios
[aHR]
95%
confidence
intervals
[CI]
computed
Cox
regression.
Results
During
a
median
follow-up
8.7
years,
6066
deaths
documented,
including
1381
cancer
206
diabetes.
Compared
no
(eating
before
22:00),
later
timing
associated
higher
risk
all-cause
mortality
(each
P
-trend
<0.05)
rather
than
highest
being
00:00–1:00
(aHR
1.38,
CI
1.02–1.88)
23:00–00:00
2.31,
1.21–4.40),
respectively.
However,
increased
risks
not
observed
for
22:00-23:00.
Likewise,
one
time
or
over
frequency
<
0.05).
That
further
in
high-dietary-energy-density
group
(all-cause
mortality:
aHR
1.21
[95%
1.06–1.38];
1.97
1.13–3.45]),
but
low-dietary-energy-density
group.
Finally,
correlation
analysis
found
positive
associations
glycohemoglobin,
fasting
glucose,
OGTT.
Conclusions
mortality;
however,
reduction
excess
when
23:00
foods.
Язык: Английский
Time-Restricted Feeding Attenuates Metabolic Dysfunction-Associated Steatohepatitis and Hepatocellular Carcinoma in Obese Male Mice
Cancers,
Год журнала:
2024,
Номер
16(8), С. 1513 - 1513
Опубликована: Апрель 16, 2024
Metabolic
dysfunction-associated
steatotic
liver
disease
(MASLD)
has
surpassed
the
hepatitis
B
virus
and
C
as
leading
cause
of
chronic
in
most
parts
Western
world.
MASLD
(formerly
known
NAFLD)
encompasses
both
simple
steatosis
more
aggressive
metabolic
steatohepatitis
(MASH),
which
is
accompanied
by
inflammation,
fibrosis,
cirrhosis,
ultimately
can
lead
to
hepatocellular
carcinoma
(HCC).
There
are
currently
very
few
approved
therapies
for
MASH.
Weight
loss
strategies
such
caloric
restriction
ameliorate
harmful
effect
MASH
inhibit
HCC;
however,
it
difficult
implement
maintain
daily
life,
especially
individuals
diagnosed
with
HCC.
In
this
study,
we
tested
a
time-restricted
feeding
(TRF)
nutritional
intervention
mouse
models
We
show
that
TRF
abrogated
dysregulation
induced
diet
without
any
calorie
or
weight
loss.
improved
insulin
sensitivity
reduced
hyperinsulinemia,
steatosis,
fibrosis.
Importantly,
inhibited
tumors
two
obesity-driven
Our
data
suggest
likely
be
effective
abrogating
HCC
warrant
further
studies
eating
humans
who
at
higher
risk
developing
Язык: Английский