Ratiometric Fluorescent Probe for Super-Resolution Imaging of Lysosome HClO in Ferroptosis Cells

Analytical Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Ferroptosis is an iron-dependent programmed cell death that characterized by the dysregulation of lipid reactive oxygen species (ROS) production, causing abnormal changes in hypochlorous acid (HClO) levels lysosomes. Super-resolution imaging can observe fine structure lysosome at nanometer level; therefore, it be used to detect HClO during ferroptosis suborganelle level. Herein, we utilize a ratiometric fluorescent probe,

Язык: Английский

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6PPD impairs growth performance by inducing intestinal oxidative stress and ferroptosis in zebrafish

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Год журнала: 2025, Номер 293, С. 110161 - 110161

Опубликована: Фев. 21, 2025

Язык: Английский

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Nanostructured aptasensors for ricin detection and tumor therapy: exploring aptamer-protein interactions and conformational stability in biological complexities

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143282 - 143282

Опубликована: Апрель 1, 2025

Язык: Английский

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Discovery of phenazine derivatives as a new class of non-classical ferroptosis inhibitors and efficacy evaluation on a mouse model of liver injury

European Journal of Medicinal Chemistry, Год журнала: 2024, Номер 282, С. 117042 - 117042

Опубликована: Ноя. 12, 2024

Язык: Английский

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Syzygium aromaticum Extract Mitigates Doxorubicin-Induced Hepatotoxicity in Male Rats

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(23), С. 12541 - 12541

Опубликована: Ноя. 22, 2024

Doxorubicin (DOX), an anticancer drug, is used to treat several types of tumors, but it has detrimental side effects that restrict its therapeutic efficacy. One the iron-dependent form ferroptosis, which characterized by elevated ROS production and iron overload.

Язык: Английский

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