Unconventional secretion of Magnaporthe oryzae effectors in rice cells is regulated by tRNA modification and codon usage control
Nature Microbiology,
Год журнала:
2023,
Номер
8(9), С. 1706 - 1716
Опубликована: Авг. 10, 2023
Язык: Английский
Effectors and environment modulating rice blast disease: from understanding to effective control
Trends in Microbiology,
Год журнала:
2024,
Номер
32(10), С. 1007 - 1020
Опубликована: Апрель 5, 2024
Язык: Английский
Characterization of Arbuscular Mycorrhizal Effector Proteins
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(11), С. 9125 - 9125
Опубликована: Май 23, 2023
Plants
are
colonized
by
various
fungi
with
both
pathogenic
and
beneficial
lifestyles.
One
type
of
colonization
strategy
is
through
the
secretion
effector
proteins
that
alter
plant's
physiology
to
accommodate
fungus.
The
oldest
plant
symbionts,
arbuscular
mycorrhizal
(AMF),
may
exploit
effectors
their
benefit.
Genome
analysis
coupled
transcriptomic
studies
in
different
AMFs
has
intensified
research
on
function,
evolution,
diversification
AMF.
However,
current
338
predicted
from
AM
fungus
Язык: Английский
Filamentous pathogen effectors enter plant cells via endocytosis
Trends in Plant Science,
Год журнала:
2023,
Номер
28(11), С. 1214 - 1217
Опубликована: Авг. 14, 2023
Recent
findings
demonstrate
that
cytoplasmic
effectors
from
fungal
and
oomycete
pathogens
enter
plant
cells
via
clathrin-mediated
endocytosis
(CME).
This
raises
several
questions:
Does
effector
secretion
pathway
facilitate
host
uptake?
How
is
CME
triggered
in
cells?
are
the
released
endosomal
compartments
to
reach
diverse
subcellular
destinations?
Язык: Английский
The Dynamic Interaction between Oil Palm and Phytophthora palmivora in Bud Rot Disease: Insights from Transcriptomic Analysis and Network Modelling
Journal of Fungi,
Год журнала:
2024,
Номер
10(3), С. 164 - 164
Опубликована: Фев. 20, 2024
Bud
Rot,
caused
by
Phytophthora
palmivora,
is
considered
one
of
the
main
diseases
affecting
African
oil
palm
(Elaeis
guineensis).
In
this
study,
we
investigated
in
vitro
molecular
dynamics
pathogen–host
interaction
analyzing
gene
expression
profiles
from
genotypes
that
were
either
susceptible
or
resistant
to
disease.
We
observed
distinct
interactions
P.
palmivora
with
and
palms
through
co-expression
network
analysis.
When
interacting
genotypes,
exhibited
upregulation
carbohydrate
sulfate
transport
genes.
These
genes
demonstrated
apoplastic
cytoplasmic
effectors,
including
cell
wall
degrading
enzymes,
elicitins,
RxLR
motif
effectors.
The
pathogen
manipulated
materials,
exacerbating
response
compromising
phenylpropanoid
pathway,
ultimately
leading
susceptibility.
contrast,
materials
control
over
their
putative
Heat
Shock
Proteins
(HSP)
maintained
homeostasis
between
primary
metabolism
biotic
defense.
Co-expressed
related
flavonoids,
WRKY
transcripts,
lectin-type
receptors,
LRR
receptors
may
play
important
roles
control.
Overall,
study
provides
new
knowledge
mechanisms
underlying
E.
guineensis
which
can
contribute
controlling
Rot
gives
insights
into
hosts.
Язык: Английский
The secreted protein FonCHRD is essential for vegetative growth, asexual reproduction, and pathogenicity in watermelon Fusarium wilt fungus
Crop Health,
Год журнала:
2024,
Номер
2(1)
Опубликована: Окт. 25, 2024
Abstract
Fungal
pathogens
often
secrete
numerous
effectors
to
interfere
with
and/or
suppress
plant
immunity
promote
their
infection.
Watermelon
Fusarium
wilt,
caused
by
the
soil-borne
fungus
oxysporum
f.
sp.
niveum
(
Fon
),
is
one
of
devastating
diseases
that
severely
affect
watermelon
industry.
Here,
we
report
function
a
candidate
effector
protein,
FonCHRD,
in
.
FonCHRD
harbors
chordin
(CHRD)
domain
unknown
and
has
signal
peptide
secretion
activity.
shows
relatively
high
expression
level
marcoconidia
inducible
root
tissues.
Phenotypic
analysis
targeted
deletion
mutant
revealed
plays
roles
vegetative
growth,
asexual
reproduction,
conidial
morphology
,
while
it
not
involved
spore
germination
as
well
cell
wall,
oxidative
salt
stress
responses.
Deletion
impaired
ability
colonize
spread
within
host
plants,
significantly
reducing
its
virulence
on
watermelon.
distributed
across
multiple
compartments
cells
but
can
target
apoplast
space
plants.
inhibits
INF1-
Bcl2-associated
X
protein-triggered
death
defense
gene
transiently
expressed
Nicotiana
benthamiana
leaves.
These
findings
suggest
essential
for
pathogenicity
modulating
invasive
growth
spreading
abilities
suppressing
immune
Язык: Английский
Paths of Least Resistance: Unconventional Effector Secretion by Fungal and Oomycete Plant Pathogens
Molecular Plant-Microbe Interactions,
Год журнала:
2024,
Номер
37(9), С. 653 - 661
Опубликована: Июль 1, 2024
Effector
secretion
by
different
routes
mediates
the
molecular
interplay
between
host
plant
and
pathogen,
but
mechanistic
details
in
eukaryotes
are
sparse.
This
may
limit
discovery
of
new
effectors
that
could
be
utilized
for
improving
disease
resistance.
In
fungi
oomycetes,
apoplastic
secreted
via
conventional
endoplasmic
reticulum
(ER)-Golgi
pathway,
while
cytoplasmic
packaged
into
vesicles
bypass
Golgi
an
unconventional
protein
(UPS)
pathway.
Язык: Английский
Transformation‐based gene silencing and functional characterization of an ISC effector reveal how a powdery mildew fungus disturbs salicylic acid biosynthesis and immune response in the plant
Jinyao Yin,
Xiao Li,
Longying Dong
и другие.
Molecular Plant Pathology,
Год журнала:
2024,
Номер
25(11)
Опубликована: Ноя. 1, 2024
Abstract
Obligate
biotrophic
powdery
mildew
fungi
infect
a
wide
range
of
economically
important
plants.
These
often
deliver
effector
proteins
into
the
host
tissues
to
suppress
plant
immunity
and
sustain
infection.
The
phytohormone
salicylic
acid
(SA)
is
one
most
signals
that
activate
against
pathogens.
However,
how
effectors
interact
with
SA
signalling
poorly
understood.
Isochorismatase
(ISC)
from
two
other
filamentous
pathogens
have
been
found
inhibit
biosynthesis
by
hydrolysing
isochorismate,
main
precursor
in
cytosol.
Here,
we
identified
an
ISC
effector,
named
EqIsc1,
rubber
tree
fungus
Erysiphe
quercicola
.
In
enzyme
assays,
EqIsc1
displayed
activity
transferring
isochorismate
2,3‐dihydro‐2,3‐dihydroxybenzoate
vitro
transgenic
Nicotiana
benthamiana
EqIsc1‐expressing
Arabidopsis
thaliana
,
SA‐mediated
immune
response
were
significantly
inhibited.
addition,
developed
electroporation‐mediated
transformation
method
for
genetic
manipulation
E.
Inoculation
leaves
‐silenced
strain
induced
immunity.
We
also
detected
translocation
cytosol
during
interaction
between
its
host.
Taken
together,
our
results
suggest
functions
as
hydrolyse
cytosol,
altering
response.
Язык: Английский
Fusarium sacchari Effector FsMEP1 Contributes to Virulence by Disturbing Localization of Thiamine Thiazole Synthase ScTHI2 from Sugarcane
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(22), С. 12075 - 12075
Опубликована: Ноя. 10, 2024
is
a
significant
pathogenic
fungus
that
causes
sugarcane
Pokkah
Boeng.
Proteins
secreted
by
fungi
can
be
delivered
into
hosts
to
suppress
plant
immunity
and
establish
infection.
However,
there
still
much
discovered
regarding
Язык: Английский
Exploring the potential role of four Rhizophagus irregularis nuclear effectors: opportunities and technical limitations
Maria Chacon,
Sofía Hernández Luelmo,
Viktor Devlieghere
и другие.
Frontiers in Plant Science,
Год журнала:
2024,
Номер
15
Опубликована: Апрель 24, 2024
Arbuscular
mycorrhizal
fungi
(AMF)
are
obligate
symbionts
that
interact
with
the
roots
of
most
land
plants.
The
genome
AMF
model
species
Rhizophagus
irregularis
contains
hundreds
predicted
small
effector
proteins
secreted
extracellularly
but
also
into
plant
cells
to
suppress
immunity
and
modify
physiology
establish
a
niche
for
growth.
Here,
we
investigated
role
four
nuclear-localized
putative
effectors,
i.e.
,
GLOIN707,
GLOIN781,
GLOIN261,
RiSP749,
in
mycorrhization
We
initially
intended
execute
functional
studies
Solanum
lycopersicum
host
economic
interest
not
previously
used
biology,
extended
our
Medicago
truncatula
as
well
non-host
Arabidopsis
thaliana
because
technical
advantages
working
these
models.
Furthermore,
three
implementation
reverse
genetic
tools,
yeast
two-hybrid
screening
whole-genome
transcriptome
analysis
revealed
potential
nuclear
targets
downstream
triggered
transcriptional
responses.
identified
validated
protein
interactors
participating
host.
S.
demonstrated
by
transcriptomics
effectors
possible
involvement
different
molecular
processes,
regulation
DNA
replication,
methylglyoxal
detoxification,
RNA
splicing.
conclude
R.
may
act
on
pathways
modulate
symbiosis
discuss
pros
cons
tools
used.
Язык: Английский