Chemosensors,
Год журнала:
2025,
Номер
13(2), С. 60 - 60
Опубликована: Фев. 8, 2025
Pathogens
and
their
metabolites
in
food
present
significant
risks
to
both
human
health
economic
development.
Rising
living
standards
increasing
awareness
of
safety
have
driven
the
demand
for
sensitive
rapid
detection
methods.
Lanthanide-doped
upconversion
nanoparticles
(UCNPs),
with
exceptional
optical
properties,
emerged
as
a
promising
platform
developing
biosensors
detect
pathogenic
bacteria
metabolites.
The
integration
UCNPs
point-of-care
testing
(POCT)
has
garnered
considerable
attention
its
portability
immediacy,
highlighting
future
biosensing,
particularly
applications
requiring
quick
accurate
diagnostics.
This
review
explores
recognition
elements
design
principles
commonly
used
UCNP-based
examines
various
applications,
including
lateral
flow
assays,
microfluidic
systems,
photoelectrochemical
devices,
smartphone-integrated
platforms.
Despite
advancements,
challenges
remain
applicability
commercialization
biosensing
technology.
Future
research
should
focus
on
enhancing
sensitivity
specificity,
scalable
cost-effective
production
methods,
integrating
advanced
digital
technologies
enable
broader
adoption.
Addressing
these
challenges,
establishing
regulatory
frameworks,
considering
sustainability
will
be
crucial
fully
realizing
potential
biosensors.
Lab on a Chip,
Год журнала:
2024,
Номер
24(5), С. 1441 - 1493
Опубликована: Янв. 1, 2024
This
review
explores
emerging
microfluidic-based
technologies
incorporating
innovative
assay
strategies
for
infectious
disease
diagnostics.
Our
classification
scheme
is
based
on
the
human
body
systems
or
pathogen
transmission
modes.
Biosensors,
Год журнала:
2022,
Номер
13(1), С. 29 - 29
Опубликована: Дек. 26, 2022
Infectious
pathogens
cause
severe
threats
to
public
health
due
their
frightening
infectivity
and
lethal
capacity.
Rapid
accurate
detection
of
is
great
significance
for
preventing
infection.
Gold
nanoparticles
have
drawn
considerable
attention
in
colorimetric
biosensing
during
the
past
decades
unique
physicochemical
properties.
Colorimetric
diagnosis
platforms
based
on
functionalized
AuNPs
are
emerging
as
a
promising
pathogen-analysis
technique
with
merits
high
sensitivity,
low-cost,
easy
operation.
This
review
summarizes
recent
development
this
field.
We
first
introduce
detecting
characteristics
gold
nanoparticles.
Four
types
strategies,
including
application
indirect
target-mediated
aggregation,
chromogenic
substrate-mediated
catalytic
activity,
point-of-care
testing
(POCT)
devices,
machine
learning-assisted
sensor
arrays,
systematically
introduced.
In
particular,
three
biomolecule-functionalized
AuNP-based
sensors
described
detail.
Finally,
we
conclude
by
presenting
our
subjective
views
present
challenges
some
appropriate
suggestions
future
research
directions
sensors.
