Academic institution extensive, building-by-building wastewater-based surveillance platform for SARS-CoV-2 monitoring, clinical data correlation, and potential national proxy DOI Creative Commons
Arnoldo Armenta-Castro, Mariel Araceli Oyervides-Muñoz, Alberto Aguayo-Acosta

и другие.

PLOS Global Public Health, Год журнала: 2025, Номер 5(5), С. e0003756 - e0003756

Опубликована: Май 9, 2025

In this work, we report on the performance of an extensive, building-by-building wastewater surveillance platform deployed across 38 locations largest private university system in Mexico, spanning 19 32 states, to detect SARS-CoV-2 genetic materials during COVID-19 pandemic. Sampling took place weekly from January 2021 and June 2022. Data 343 sampling sites was clustered by campus state evaluated through its correlation with seven-day average daily new cases each cluster. Statistically significant linear correlations (p-values below 0.05) were found 25 campuses 13 states. Moreover, evaluate effectiveness epidemiologic containment measures taken institution potential as representative points for future public health emergencies Monterrey Metropolitan Area, between viral loads samples be stronger Dulces Nombres, treatment plant city (Pearson coefficient: 0.6456, p-value: 6.36710 −8 ), than study 0.4860, 8.288x10 −5 ). However, when comparing data after urban mobility returned pre-pandemic levels, levels both became comparable (0.894 0.865 Nombres). This work provides a basic framework implementation analysis similar decentralized platforms address sanitary emergencies, allowing efficient return priority in-person activities while preventing becoming transmission hotspots.

Язык: Английский

Deep learning techniques for detection and prediction of pandemic diseases: a systematic literature review DOI Creative Commons
Sunday Adeola Ajagbe, Matthew O. Adigun

Multimedia Tools and Applications, Год журнала: 2023, Номер 83(2), С. 5893 - 5927

Опубликована: Май 29, 2023

Abstract Deep learning (DL) is becoming a fast-growing field in the medical domain and it helps timely detection of any infectious disease (IDs) essential to management diseases prediction future occurrences. Many scientists scholars have implemented DL techniques for pandemics, IDs other healthcare-related purposes, these outcomes are with various limitations research gaps. For purpose achieving an accurate, efficient less complicated DL-based system therefore, this study carried out systematic literature review (SLR) on pandemics using techniques. The survey anchored by four objectives state-of-the-art forty-five papers seven hundred ninety retrieved from different scholarly databases was analyze evaluate trend application areas pandemics. This used tables graphs extracted related articles online repositories analysis showed that good tool pandemic prediction. Scopus Web Science given attention current because they contain suitable scientific findings subject area. Finally, presents forty-four (44) studies technique performances. challenges identified include low performance model due computational complexities, improper labeling absence high-quality dataset among others. suggests possible solutions such as development improved or reduction output layer architecture pandemic-prone considerations.

Язык: Английский

Процитировано

79

Opportunities and limits of wastewater-based epidemiology for tracking global health and attainment of UN sustainable development goals DOI Creative Commons
Sangeet Adhikari, Rolf U. Halden

Environment International, Год журнала: 2022, Номер 163, С. 107217 - 107217

Опубликована: Март 27, 2022

Wastewater-based epidemiology (WBE) emerged as a powerful, actionable health management tool during the COVID-19 pandemic. Hypothesizing future uses, we explored its potential for real-time, tracking of progress in attaining United Nations Sustainable Development Goals (SDGs) globally non-expensive method using existing infrastructure. We inventoried (i) literature-documented sewerage infrastructure, (ii) demographics populations served, and (iii) WBE markers informative 9 SDGs. Among 17 different sustainable development goals listed by UN 2030 agenda, more than half these may be monitored monitoring at centralized treatment infrastructure tabulated this study. Driven mainly COVID-19, currently is practiced least 55 countries, reaching about 300 million people. Expansion to 109,000 + plants 129 countries would increase global coverage 9-fold 34.7% or 2.7 billion, leaving out 5 billion people not served systems. Associations between population present-day are explored, geospatial regions particularly vulnerable infectious disease outbreaks identified. The results suggest that difference differential outcomes well-being an outcome sanitation inequalities lack creates doubly disadvantaged risk poor hygiene cut off from early-warning benefits conventional WBE. This first study explore feasibility barriers use attainment SDGs with

Язык: Английский

Процитировано

76

Nanofarming: Promising Solutions for the Future of the Global Agricultural Industry DOI Creative Commons
Hassan El-Ramady, Neama Abdalla,

Daniella Sári

и другие.

Agronomy, Год журнала: 2023, Номер 13(6), С. 1600 - 1600

Опубликована: Июнь 13, 2023

The agricultural sector is a vital source of human well-being that provides the necessities daily life. A variety farming systems are utilized in agriculture, such as wide range tillage options, no-till, agroforestry, precision farming, organic cover cropping, crop rotations, etc. Each these has unique challenges, and nanotechnology successfully improved on many them. Agricultural applications include nanofertilizers, nanopesticides, nanosensors, nanobiotechnology, nanoremediation. This study focuses application nano-farming technologies to different systems. Suggested practices nano improvement soil quality, nano-protection under biotic stress, nanoremediation polluted water environments, nanomanagement agro-wastes, nano-agrochemicals, nano-precision nanobiotechnology for modern farming. review also addresses expected problems may occur due over nanomaterials systems, nanopollution nanotoxicity agroecosystem compartments. Several dimensions emphasized this study, green energy, sustainable development, circular bioeconomy, land biodegradation, pollution, one health approach, essential global goals development. Nanofarming presents both benefits obstacles exact balance between challenges needs more study.

Язык: Английский

Процитировано

45

Microplastics and other emerging contaminants in the environment after COVID-19 pandemic: The need of global reconnaissance studies DOI Open Access
Yolanda Picó, ‪Damià Barceló

Current Opinion in Environmental Science & Health, Год журнала: 2023, Номер 33, С. 100468 - 100468

Опубликована: Апрель 11, 2023

Язык: Английский

Процитировано

32

Emerging technologies revolutionising disease diagnosis and monitoring in aquatic animal health DOI Creative Commons
Kailash Bohara, Pabitra Joshi, Krishna Prasad Acharya

и другие.

Reviews in Aquaculture, Год журнала: 2023, Номер 16(2), С. 836 - 854

Опубликована: Окт. 30, 2023

Abstract In recent years, aquaculture has seen tremendous growth worldwide due to technological advancements, leading research and development of various innovations. Aquaculture farmers prioritise early diagnosis for timely treatment achieve better productive economic performance. Aquatic animal health experts still employ traditional diagnostic methods using visual diagnosis, cell culture, media histopathology serology. However, the developments technologies in aquamedicine, such as sequencing, biosensors CRISPR, have enabled rapid disease detection within minutes. Furthermore, integrating sensors, drones, artificial intelligence internet farm monitoring helped take decisive actions improve production. Advancements techniques significantly enhanced efficient bacterial, viral, parasitic fungal diseases aquatic animals. Moreover, water quality, behaviour on farms become exceptionally streamlined with cutting‐edge tools like sensors intelligence. Summarising aids technology adoption aquaculture. With these advanced technologies' continued developed countries, industry is experiencing increased efficiency, benefiting consumers regions. educators developing countries lack information about technologies. Training agricultural dissemination knowledge through advertising publication collaboration companies essential. This review delves into emerging capable replacing conventional utilised We also explore their strengths, limitations potential future applications settings.

Язык: Английский

Процитировано

30

Wastewater surveillance for viral pathogens: A tool for public health DOI Creative Commons
Matheus Carmo dos Santos,

Ana Clara Cerqueira Silva,

Carine dos Reis Teixeira

и другие.

Heliyon, Год журнала: 2024, Номер 10(13), С. e33873 - e33873

Опубликована: Июнь 29, 2024

A focus on water quality has intensified globally, considering its critical role in sustaining life and ecosystems. Wastewater, reflecting societal development, profoundly impacts public health. Wastewater-based epidemiology (WBE) emerged as a surveillance tool for detecting outbreaks early, monitoring infectious disease trends, providing real-time insights, particularly vulnerable communities. WBE aids tracking pathogens, including viruses, sewage, offering comprehensive understanding of community health lifestyle habits. With the rise global COVID-19 cases, gained prominence, aiding SARS-CoV-2 levels worldwide. Despite advancements treatment, poorly treated wastewater discharge remains threat, amplifying spread water-, sanitation-, hygiene (WaSH)-related diseases. WBE, serving complementary surveillance, is pivotal community-level viral infections. However, there untapped potential to expand surveillance. This review emphasizes importance link between health, highlighting need further integration into management.

Язык: Английский

Процитировано

14

Optical biosensors for the detection of foodborne pathogens: recent development and future prospects DOI
Yuhe Wang,

Kaiyuan Jia,

Jianhan Lin

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 177, С. 117785 - 117785

Опубликована: Май 22, 2024

Язык: Английский

Процитировано

11

Integration of microfluidic chips with biosensors DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu,

Sivarasu Sudesh

и другие.

Deleted Journal, Год журнала: 2024, Номер 6(9)

Опубликована: Авг. 23, 2024

Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.

Язык: Английский

Процитировано

11

A review of wastewater-based epidemiology for antimicrobial resistance surveillance DOI Open Access

Leah Clarke,

Jake O’Brien, Aimee K. Murray

и другие.

Journal of Environmental Exposure Assessment, Год журнала: 2024, Номер 3(1)

Опубликована: Фев. 26, 2024

Antimicrobial resistance (AMR) is recognized as one of the most serious threats to public health. Unparalleled population growth and accelerated rates AMR emergence dissemination have resulted in both novel pathogenic organisms re-appearance infections that were formerly under control. Consequently, this has led an increased quantity infectious diseases. One main drivers antimicrobial overuse inappropriate prescribing human veterinary medicine. The ability rapidly survey spread within populations key for its prevention, intervention, However, many constraints are present current clinical surveillance systems their capacity determine dynamics microbiome healthy individuals well pathogens causing infections. Wastewater-based epidemiology (WBE) emergent technique act a supplementary measure disease early warning system outbreaks. development outbreaks community level can be monitored real time through analysis pooled wastewater. This review provides introduction using wastewater-based monitor bacteria, overview components.

Язык: Английский

Процитировано

10

Optimization of a 6-plex Crystal Digital PCR® assay and its application to simultaneous surveillance of enteric and respiratory viruses in wastewater DOI Creative Commons
Bikash Malla, Sadhana Shrestha, Eiji Haramoto

и другие.

The Science of The Total Environment, Год журнала: 2025, Номер 970, С. 178939 - 178939

Опубликована: Март 1, 2025

Multiplex digital PCR (dPCR) approaches are commonly employed in wastewater-based epidemiology (WBE) studies. However, optimizing the dPCR workflow is a critical step to ensure its reliability and accuracy before application. In this study, 6-plex Crystal Digital PCR® (cdPCR) was optimized for simultaneous detection of six epidemiologically important pathogens, including three enteric viruses, noroviruses genogroups I II (NoV-GI GII) enteroviruses (EnV), respiratory severe acute syndrome coronavirus 2 (SARS-CoV-2), which causative agent disease 2019 (COVID-19), influenza A virus (InfA), syncytial B (RSVB), wastewater. Four cDNA input ratios (20 %-70 %) two extraction kits were evaluated optimization, with 30 % AllPrep PowerViral DNA/RNA Kit (Qiagen) exhibiting optimal performance. The cdPCR assay applied year-long wastewater surveillance study Japan (n = 52), revealing distinct trends prevalence viruses. NoV-GII detected 96 samples highest mean concentration (6.1 ± 0.6 log10 copies/L), while SARS-CoV-2 InfA 60 50 samples, respectively, reflected circulation these pathogens within community. Notably, RSVB less frequently (25 %), line fewer cases reported during period. concentrations EnV showed significant positive correlations hand foot mouth herpangina cases, respectively. no observed RSV COVID-19, possibly due testing RSVA more prevalent also cluster outbreaks. These findings demonstrated utility detecting provided insights into community trends, representing an advancement WBE.

Язык: Английский

Процитировано

1