The Analyst, Год журнала: 2024, Номер 149(17), С. 4322 - 4342
Опубликована: Янв. 1, 2024
Biomedical silk protein optics has become the subject of intensive research aimed at solving challenges associated with traditional medical devices in terms biocompatibility and performance balance.
Язык: Английский
Environmental Research, Год журнала: 2024, Номер 251, С. 118610 - 118610
Опубликована: Март 3, 2024
Язык: Английский
Процитировано
23
Chemical Reviews, Год журнала: 2024, Номер 124(20), С. 11242 - 11347
Опубликована: Окт. 9, 2024
Biopsy, including tissue and liquid biopsy, offers comprehensive real-time physiological pathological information for disease detection, diagnosis, monitoring. Fluorescent probes are frequently selected to obtain adequate on processes in a rapid minimally invasive manner based their advantages biopsy. However, conventional fluorescent have been found show aggregation-caused quenching (ACQ) properties, impeding greater progresses this area. Since the discovery of aggregation-induced emission luminogen (AIEgen) promoted advancements molecular bionanomaterials owing unique high quantum yield (QY) signal-to-noise ratio (SNR),
Язык: Английский
Процитировано
18
TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 169, С. 117386 - 117386
Опубликована: Окт. 20, 2023
Язык: Английский
Процитировано
28
Microchemical Journal, Год журнала: 2025, Номер 209, С. 112734 - 112734
Опубликована: Янв. 10, 2025
Язык: Английский
Процитировано
1
Aggregate, Год журнала: 2025, Номер unknown
Опубликована: Янв. 15, 2025
ABSTRACT Colorectal cancer (CRC) screening and early diagnosis is an effective strategy for reducing CRC mortality. However, the current detection methods involve exorbitant costs complex procedures, which are inconvenient large‐scale screening. Given its high prevalence in malignant tissues feces of patients, Fusobacterium nucleatum ( F. ) has emerged as a crucial biomarker CRC. Herein, we propose ‐specific recognition diagnosis. A novel nanobioprobe (AIE‐Pep) with aggregation‐induced emission (AIE) characteristics was synthesized by conjugating red/near‐infrared (NIR) emissive AIE luminogen (AIEgen) FadA‐targeting peptide (ASANWTIQYND). The robust binding affinity between FadA on allows AIE‐Pep NPs to adhere selectively , emits strong red/NIR fluorescence. In model orthotopic CRC, can precisely localize around Moreover, demonstrated limit (LOD) 82.97 CFU/mL could significantly differentiate mice from those normal mice. Overall, this study presents pivotal approach specifically identifying holds immense potential
Язык: Английский
Процитировано
1
Microchimica Acta, Год журнала: 2024, Номер 191(6)
Опубликована: Май 10, 2024
Abstract The COVID-19 pandemic underlines the need for effective strategies controlling virus spread and ensuring sensitive detection of SARS-CoV-2. This review presents potential nanomaterial-enabled optical biosensors rapid low-cost SARS-CoV-2 biomarkers, demonstrating a comprehensive analysis including colorimetric, fluorescence, surface-enhanced Raman scattering, surface plasmon resonance methods. Nanomaterials metal-based nanomaterials, metal–organic frame–based nanoparticles, nanorods, nanoporous materials, nanoshell magnetic nanoparticles employed in production are presented detail. also discusses principles, fabrication methods, nanomaterial synthesis, their applications four categories: antibody-based, antigen-based, nucleic acid–based, aptamer-based biosensors. critical includes reports published literature between years 2021 2024. In addition, offers insights into nanobiosensors diagnosis COVID-19. integration artificial intelligence machine learning technologies with is proposed to improve efficiency diagnostic systems future scenarios. Graphical
Язык: Английский
Процитировано
7
Microchemical Journal, Год журнала: 2024, Номер 200, С. 110267 - 110267
Опубликована: Март 1, 2024
Язык: Английский
Процитировано
5
TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 169, С. 117368 - 117368
Опубликована: Окт. 12, 2023
Язык: Английский
Процитировано
12
Molecules, Год журнала: 2023, Номер 28(23), С. 7889 - 7889
Опубликована: Дек. 1, 2023
In this study, a fluorescence resonance energy transfer (FRET)-based aptasensor for the detection of aflatoxin B1 (AFB1) was designed using carboxyfluorescein (FAM)-labeled aptamer and short complementary DNA (cDNA) labeled with low molecular quencher RTQ1. The sensing principle based on restored FAM-aptamer due to ligand-induced displacement cDNA in presence AFB1, leading destruction aptamer/cDNA duplex preventing convergence FAM RTQ1 at effective FRET distance. Under optimal conditions, linear correlation obtained between intensity AFB1 concentration range 2.5–208.3 ng/mL limit assay equal 0.2 ng/mL. time 30 min. proposed has been successfully validated by analyzing white wine corn flour samples, recovery ranging from 76.7% 91.9% 84.0% 86.5%, respectively. This work demonstrates possibilities as an easily accessible tool sensitive detection. homogeneous is appropriate choice contaminant screening complex matrices.
Язык: Английский
Процитировано
12
Journal of Molecular Histology, Год журнала: 2024, Номер 55(4), С. 581 - 588
Опубликована: Май 17, 2024
Язык: Английский
Процитировано
4