Nano TransMed, Год журнала: 2025, Номер unknown, С. 100080 - 100080
Опубликована: Март 1, 2025
Язык: Английский
Clinica Chimica Acta, Год журнала: 2025, Номер 568, С. 120125 - 120125
Опубликована: Янв. 8, 2025
Язык: Английский
Процитировано
1
Acta Biomaterialia, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1
Analytica Chimica Acta, Год журнала: 2025, Номер 1345, С. 343743 - 343743
Опубликована: Янв. 31, 2025
Язык: Английский
Процитировано
1
Microchimica Acta, Год журнала: 2025, Номер 192(4)
Опубликована: Март 5, 2025
The review article provides a short introduction to exosomes with the focus use as disease markers itself (i.e. their concentration or presence of some specific receptors) source biomarkers such proteins and metabolites. In detail, we are discussing various methods exosome isolation main paper is on affinity capture exosomes, since them can be applied sub-populations produced by organs. comprehensive overview magnetic (bio)affinity detection exosomal cargo using different ligands antibodies, DNA aptamers, peptides, glycan-based recognition, transferrin-based approaches, based recognition phospholipids other approaches including electrostatic interactions. in detail key analytical clinical parameters form an extensive table summarising outcomes published last two years (2023-2024). Finally, also conclusions sections pros cons for and/or determination content.
Язык: Английский
Процитировано
1
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(22), С. 12092 - 12092
Опубликована: Ноя. 11, 2024
Plant-derived exosome-like nanoparticles (PELNs) are a type of membranous vesicle isolated from plant tissues. They contain proteins, lipids, nucleic acids, and other components. PELNs involved in the defensive response to pathogen attacks by exerting anti-inflammatory, antiviral, antifibrotic, antitumor effects through substances they contain. Most edible can be used as carriers for delivering specific drugs without toxicity side effects, making them hot topic research. Sources abundantly, produced high yields, with low risk developing immunogenicity vivo. This paper summarizes formation, isolation, purification methods; physical properties; composition comprehensive literature search. It also analyzes biomedical applications PELNs, well future research directions. provides new ideas methods on PELNs.
Язык: Английский
Процитировано
4
Cancer Medicine, Год журнала: 2025, Номер 14(1)
Опубликована: Янв. 1, 2025
ABSTRACT Background Cancer is the second leading cause of human mortality worldwide. Extracellular vesicles (EVs) from liquid biopsy samples are used in early cancer detection, characterization, and surveillance. Exosomes a subset EVs produced by all cells present body fluids. They play an important role development because they active transporters capable carrying contents any type cell. The objective this review was to provide brief overview clinical implication exosomes or exosomal components diagnosis prognosis. Methods An extensive current literature their prognosis were carried out study. Results Tumor release that contribute formation pre‐metastatic microenvironment, angiogenesis, invasion, treatment resistance. On contrary, tumor more than normal cells, these tumor‐specific can carry genomic proteomic signature which act as tools for patients with cancers. Conclusion This information may help clinicians improve management settings future.
Язык: Английский
Процитировано
0
International Journal of Biological Macromolecules, Год журнала: 2025, Номер 296, С. 139698 - 139698
Опубликована: Янв. 9, 2025
Язык: Английский
Процитировано
0
Cosmetics, Год журнала: 2025, Номер 12(1), С. 9 - 9
Опубликована: Янв. 13, 2025
This study addresses a significant gap in the clinical validation and standardization of exosome-based applications within domains cosmetics regenerative medicine. Despite offering thorough overview potential therapeutic benefits underlying mechanisms exosomes, manuscript underscores several unresolved challenges, including paucity evidence, regulatory barriers, inconsistencies standardization, incomplete mechanistic understanding. The primary aim this research is to conduct systematic comprehensive review existing studies on exosomes skincare. To achieve this, literature was performed, drawing major medical database PubMed. approach facilitated collection meta-analysis relevant data, ensuring rigorous assessment recent advancements exosome research. main outcomes highlight multifaceted roles promoting skin rejuvenation mitigating signs aging. Specific discussed include pigmentation correction, wound healing, tissue repair, innovative delivery mechanisms. Moreover, examines emerging plastic surgery Challenges limitations, such as constraints, hurdles, need for further validation, are critically analyzed, providing framework future directions.
Язык: Английский
Процитировано
0
Advanced Drug Delivery Reviews, Год журнала: 2025, Номер 218, С. 115522 - 115522
Опубликована: Янв. 22, 2025
Язык: Английский
Процитировано
0
Stem Cell Research & Therapy, Год журнала: 2025, Номер 16(1)
Опубликована: Янв. 23, 2025
Interest in prostate cancer as a research topic has gradually increased. As result, series of innovative treatment strategies have emerged with an in-depth understanding the disease. Owing to their unique biological characteristics, mesenchymal stromal cell exosomes (MSC-Exos) garnered significant attention for potential deliver targeted drugs and enable precise treatment. Herein, MSC-Exos drug-delivery systems is reviewed. This review provides comprehensive introduction advantages these systems, current trends progress, well analysis challenges future directions. Moreover, this lays solid foundation continued development application MSC-Exos.
Язык: Английский
Процитировано
0