Metagenomic surveillance of antibiotic resistome in influent and effluent of wastewater treatment plants located on the Qinghai-Tibetan Plateau

The Science of The Total Environment, Год журнала: 2023, Номер 870, С. 162031 - 162031

Опубликована: Фев. 4, 2023

Язык: Английский

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Metagenome sequencing reveals shifts in phage-associated antibiotic resistance genes from influent to effluent in wastewater treatment plants

Water Research, Год журнала: 2024, Номер 253, С. 121289 - 121289

Опубликована: Фев. 8, 2024

Язык: Английский

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Dissemination of antibiotic resistance genes from aboveground sources to groundwater in livestock farms

Water Research, Год журнала: 2024, Номер 256, С. 121584 - 121584

Опубликована: Апрель 9, 2024

Язык: Английский

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Health risk ranking of antibiotic resistance genes in the Yangtze River

Environmental Science and Ecotechnology, Год журнала: 2024, Номер 21, С. 100388 - 100388

Опубликована: Янв. 3, 2024

Antibiotic resistance is an escalating global health concern, exacerbated by the pervasive presence of antibiotic genes (ARGs) in natural environments. The Yangtze River, world's third-longest river, traversing areas with intense human activities, presents a unique ecosystem for studying impact these on health. Here, we explored ARGs examining 204 samples from six distinct habitats approximately 6000 km including free-living and particle-associated settings, surface bottom sediments, bank soils. Employing shotgun sequencing, generated average 13.69 Gb reads per sample. Our findings revealed significantly higher abundance diversity water-borne bacteria compared to other habitats. A notable pattern resistome coalescence was observed within similar habitat types. In addition, created accurate framework ranking risk ARG corresponding method calculating index. Applying them, identified as highest contributors risks, noted increase risks correlating heightened anthropogenic activities. Further analysis using weighted index pinpointed Chengdu–Chongqing River Delta urban agglomerations regions elevated risk. These insights provide critical new perspective assessment, highlighting urgent need strategies mitigate preserve ecological economic sustainability future use.

Язык: Английский

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Profiles of antibiotic resistome risk in diverse water environments

Communications Earth & Environment, Год журнала: 2025, Номер 6(1)

Опубликована: Фев. 27, 2025

Язык: Английский

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Source-oriented ecological and resistome risks associated with geochemical enrichment of heavy metals in river sediments

Chemosphere, Год журнала: 2023, Номер 336, С. 139119 - 139119

Опубликована: Июнь 9, 2023

Язык: Английский

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Microplastic and antibiotic proliferated the colonization of specific bacteria and antibiotic resistance genes in the phycosphere of Chlorella pyrenoidosa

Journal of Hazardous Materials, Год журнала: 2023, Номер 455, С. 131618 - 131618

Опубликована: Май 11, 2023

Язык: Английский

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Antibiotic resistome associated with inhalable bioaerosols from wastewater to atmosphere: Mobility, bacterial hosts, source contributions and resistome risk

Water Research, Год журнала: 2023, Номер 243, С. 120403 - 120403

Опубликована: Июль 24, 2023

Язык: Английский

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Selective enrichment of high-risk antibiotic resistance genes and priority pathogens in freshwater plastisphere: Unique role of biodegradable microplastics

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 135901 - 135901

Опубликована: Сен. 19, 2024

Язык: Английский

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Hydraulic conditions control the abundance of antibiotic resistance genes and their potential host microorganisms in a frequently regulated river–lake system

The Science of The Total Environment, Год журнала: 2024, Номер 946, С. 174143 - 174143

Опубликована: Июнь 20, 2024

Antibiotic resistance genes (ARGs) are a growing problem that is widespread in river-lake ecosystems, where they pose threat to the aquatic environment's health and public safety. These systems serve as critical nodes water management, facilitate equitable allocation of resources through long-term frequent diversions. However, hydrological disturbances associated with water-regulation practices can influence dynamics their potential host microorganisms genes. Consequently, identifying key ARGs mechanisms heavily regulated waters vital for safeguarding human ecosystems. In this study, we examined impact factors on hosts within continuum using 16S rRNA metagenomic sequencing. We found significant increase ARG abundance during regulation periods (p < 0.05), especially environment. Key were macB, tetA, evgS, novA, msbA, increased efflux pinpointed principal mechanism. Network analysis identified Flavobacteriales, Acinetobacter, Pseudomonas, Burkholderiaceae, Erythrobacter microorganisms, which showed column 0.05). Flow velocity depth both drove ARGs. Our findings underscore importance monitoring mitigating antibiotic risk transfers systems, thereby supporting informed management conservation strategies.

Язык: Английский

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