Photothermal amplified multizyme activity for synergistic photothermal-catalytic tumor therapy

Journal of Colloid and Interface Science, Год журнала: 2024, Номер 679, С. 375 - 383

Опубликована: Сен. 28, 2024

Язык: Английский

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Recent advances of piezoelectric materials used in sonodynamic therapy of tumor

Coordination Chemistry Reviews, Год журнала: 2024, Номер 523, С. 216282 - 216282

Опубликована: Окт. 22, 2024

Язык: Английский

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Catalytic Biomaterials‐Activated In Situ Chemical Reactions: Strategic Modulation and Enhanced Disease Treatment

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 5, 2024

Abstract Chemical reactions underpin biological processes, and imbalances in critical biochemical pathways within organisms can lead to the onset of severe diseases. Within this context, emerging field “Nanocatalytic Medicine” leverages nanomaterials as catalysts modulate fundamental chemical specific microenvironments This approach is designed facilitate targeted synthesis localized accumulation therapeutic agents, thus enhancing treatment efficacy precision while simultaneously reducing systemic side effects. The effectiveness these nanocatalytic strategies critically hinges on a profound understanding kinetics intricate interplay particular pathological ensure effective catalytic actions. review methodically explores situ their associated biomaterials, emphasizing regulatory that control responses. Furthermore, discussion encapsulates crucial elements‐reactants, catalysts, reaction conditions/environments‐necessary for optimizing thermodynamics reactions, rigorously addressing both biophysical dimensions disease enhance outcomes. It seeks clarify mechanisms underpinning biomaterials evaluate potential revolutionize across various conditions.

Язык: Английский

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Nano-Based Strategies Aiming at Tumor Microenvironment for Improved Cancer Therapy

Molecular Pharmaceutics, Год журнала: 2025, Номер unknown

Опубликована: Янв. 17, 2025

Malignant tumors pose a considerable threat to human life and health. Traditional treatments, such as radiotherapy chemotherapy, often lack specificity, leading collateral damage normal tissues. Tumor microenvironment (TME) is characterized by hypoxia, acidity, redox imbalances, elevated ATP levels factors that collectively promote tumor growth metastasis. This review provides comprehensive overview of the nanoparticles developed in recent years for TME-responsive strategies or TME-modulating methods therapy. The focus on designing synthesizing can interact with achieve precisely controlled drug release. These activate release under specific conditions within environment, thereby enhancing efficacy drugs while reducing toxicity cells. Moreover, simply eliminating cells does not fundamentally solve problem. Only comprehensively regulating TME make it unsuitable cell survival proliferation we more thorough therapeutic effects reduce risk recurrence. regulation aim suppress metastasis modulating various components TME. only improve treatment outcomes but also have potential lay foundation future personalized cancer therapies.

Язык: Английский

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Manganese Empowered Electronic Modulated Nanocatalysts Facilitate Bone Reconstruction via Osteoclastogenesis Inhibition and Osteogenesis Activation Bistimulatory Strategy

Composites Part B Engineering, Год журнала: 2025, Номер unknown, С. 112364 - 112364

Опубликована: Март 1, 2025

Язык: Английский

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Catalytic biomaterials, catalytic biology and catalytic medicine

Science Bulletin, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Photocatalytic Degradation of Synozol Navy Blue Dye by Ni‐Cu‐Ag Dopped ZnO: An Insight Into Photoluminescence, Scavenging, Mechanism and Kinetic Aspects

Microscopy Research and Technique, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

ABSTRACT Cost‐effective, sustainable, and eco‐friendly strategies are crucial for treating organic pollutants in industrial wastewater. ZnO is a promising photocatalyst due to its affordability, environmentally benign nature, ability fully mineralize pollutants. However, limited effectiveness under visible light major drawback. Ni doping helps reduce charge carrier recombination, enhancing the photocatalytic activity of ZnO. Ni‐Cu co‐doping increases saturation magnetization by creating intrinsic defects, though it can lead nanocluster formation on catalyst surface. Ag further improves performance preventing aggregation prolonging lifetimes. In this study, Ni‐Cu‐Ag@ZnO nanoparticles were synthesized via sol–gel method used as degradation Synozol navy blue dye. Characterization techniques like FTIR, SEM, XRD, EDX, BET, UV, PL confirmed nanocomposite structure morphology. The achieved 88% photodegradation efficiency optimal conditions (a contact time 50 min, an initial dye concentration 75 ppm, dosage 0.03 g, acidic medium with pH 2). rate constants, k 1 (2 × 10 −2 min −1 ) suggest that ordinary follows pseudo‐first‐order kinetics. Scavenging tests enhanced was driven generation OH • radicals, addition hydrogen peroxide playing key role electron–hole recombination. This indicates quantity hydroxyl radicals their adsorption determining extent degradation. study highlights potential nanocomposites wastewater treatment opens new avenues enhancement other catalysts consideration.

Язык: Английский

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Regulating Manganese-Site Electronic Structure via Reconstituting Nitrogen Coordination for Efficient Non-Oxygen-Dependent Sonocatalytic Therapy against Orthotopic Breast Cancer

ACS Nano, Год журнала: 2024, Номер unknown

Опубликована: Сен. 26, 2024

Sonocatalytic therapy (SCT) has emerged as a promising noninvasive modality for tumor treatment but is hindered by the insufficient generation of ultrasound-induced reactive oxygen species (ROS) and hypoxic microenvironments. Herein, we fabricated carbon nanoframe-confined N-coordinated manganese single-atom sonocatalyst with five-coordinated structure (MnN

Язык: Английский

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Fabricating PDA-NOate@CuS coated NIR-activable titanium implant to realize simultaneous antiinfection and osseointegration

New Journal of Chemistry, Год журнала: 2024, Номер 48(25), С. 11465 - 11475

Опубликована: Янв. 1, 2024

A good biocompatible multifunctional Ti implant was constructed, which exhibits synergistic antibacterial activity through photothermal and NO effects, promotes osseointegration.

Язык: Английский

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Au/CeO₂ Nanozyme Scaffold Boosts Electron and Hydrogen Transfer for NIR-Enhanced Chemodynamic Therapy

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

CeO

Язык: Английский

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