Recent advances of piezoelectric materials used in sonodynamic therapy of tumor

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 523, P. 216282 - 216282

Published: Oct. 22, 2024

Language: Английский

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Photothermal amplified multizyme activity for synergistic photothermal-catalytic tumor therapy

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 679, P. 375 - 383

Published: Sept. 28, 2024

Language: Английский

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Nano-Based Strategies Aiming at Tumor Microenvironment for Improved Cancer Therapy

Molecular Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Malignant tumors pose a considerable threat to human life and health. Traditional treatments, such as radiotherapy chemotherapy, often lack specificity, leading collateral damage normal tissues. Tumor microenvironment (TME) is characterized by hypoxia, acidity, redox imbalances, elevated ATP levels factors that collectively promote tumor growth metastasis. This review provides comprehensive overview of the nanoparticles developed in recent years for TME-responsive strategies or TME-modulating methods therapy. The focus on designing synthesizing can interact with achieve precisely controlled drug release. These activate release under specific conditions within environment, thereby enhancing efficacy drugs while reducing toxicity cells. Moreover, simply eliminating cells does not fundamentally solve problem. Only comprehensively regulating TME make it unsuitable cell survival proliferation we more thorough therapeutic effects reduce risk recurrence. regulation aim suppress metastasis modulating various components TME. only improve treatment outcomes but also have potential lay foundation future personalized cancer therapies.

Language: Английский

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Catalytic Biomaterials‐Activated In Situ Chemical Reactions: Strategic Modulation and Enhanced Disease Treatment

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

Abstract Chemical reactions underpin biological processes, and imbalances in critical biochemical pathways within organisms can lead to the onset of severe diseases. Within this context, emerging field “Nanocatalytic Medicine” leverages nanomaterials as catalysts modulate fundamental chemical specific microenvironments This approach is designed facilitate targeted synthesis localized accumulation therapeutic agents, thus enhancing treatment efficacy precision while simultaneously reducing systemic side effects. The effectiveness these nanocatalytic strategies critically hinges on a profound understanding kinetics intricate interplay particular pathological ensure effective catalytic actions. review methodically explores situ their associated biomaterials, emphasizing regulatory that control responses. Furthermore, discussion encapsulates crucial elements‐reactants, catalysts, reaction conditions/environments‐necessary for optimizing thermodynamics reactions, rigorously addressing both biophysical dimensions disease enhance outcomes. It seeks clarify mechanisms underpinning biomaterials evaluate potential revolutionize across various conditions.

Language: Английский

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Regulating Manganese-Site Electronic Structure via Reconstituting Nitrogen Coordination for Efficient Non-Oxygen-Dependent Sonocatalytic Therapy against Orthotopic Breast Cancer

ACS Nano, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 26, 2024

Sonocatalytic therapy (SCT) has emerged as a promising noninvasive modality for tumor treatment but is hindered by the insufficient generation of ultrasound-induced reactive oxygen species (ROS) and hypoxic microenvironments. Herein, we fabricated carbon nanoframe-confined N-coordinated manganese single-atom sonocatalyst with five-coordinated structure (MnN

Language: Английский

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Manganese Empowered Electronic Modulated Nanocatalysts Facilitate Bone Reconstruction via Osteoclastogenesis Inhibition and Osteogenesis Activation Bistimulatory Strategy

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112364 - 112364

Published: March 1, 2025

Language: Английский

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Catalytic biomaterials, catalytic biology and catalytic medicine

Science Bulletin, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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Photocatalytic Degradation of Synozol Navy Blue Dye by Ni‐Cu‐Ag Dopped ZnO: An Insight Into Photoluminescence, Scavenging, Mechanism and Kinetic Aspects

Microscopy Research and Technique, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

ABSTRACT Cost‐effective, sustainable, and eco‐friendly strategies are crucial for treating organic pollutants in industrial wastewater. ZnO is a promising photocatalyst due to its affordability, environmentally benign nature, ability fully mineralize pollutants. However, limited effectiveness under visible light major drawback. Ni doping helps reduce charge carrier recombination, enhancing the photocatalytic activity of ZnO. Ni‐Cu co‐doping increases saturation magnetization by creating intrinsic defects, though it can lead nanocluster formation on catalyst surface. Ag further improves performance preventing aggregation prolonging lifetimes. In this study, Ni‐Cu‐Ag@ZnO nanoparticles were synthesized via sol–gel method used as degradation Synozol navy blue dye. Characterization techniques like FTIR, SEM, XRD, EDX, BET, UV, PL confirmed nanocomposite structure morphology. The achieved 88% photodegradation efficiency optimal conditions (a contact time 50 min, an initial dye concentration 75 ppm, dosage 0.03 g, acidic medium with pH 2). rate constants, k 1 (2 × 10 −2 min −1 ) suggest that ordinary follows pseudo‐first‐order kinetics. Scavenging tests enhanced was driven generation OH • radicals, addition hydrogen peroxide playing key role electron–hole recombination. This indicates quantity hydroxyl radicals their adsorption determining extent degradation. study highlights potential nanocomposites wastewater treatment opens new avenues enhancement other catalysts consideration.

Language: Английский

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Recent Advances in Thermoelectric Materials for Biomedical Applications: Energy Harvesting and Wearables

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: May 7, 2025

Recent advances in thermoelectric materials are transforming biomedicine, particularly for energy harvesting and wearables. This chapter reviews generators (TEGs) utilizing the Seebeck effect to convert body heat into electricity, powering self-sufficient medical devices like implants monitors. Performance metrics, including figures of merit (ZT) power factors, detailed, highlighting such as bismuth telluride (Bi2Te3) carbon nanotube composites achieving ZT values over 1.0 at room temperature. The covers: (1) novel nanocomposites, exploring nanostructured enhanced efficiency; (2) low-temperature thermoelectrics, focusing on magnesium silicide (Mg2Si) organic polymers wearables; (3) future challenges, addressing scalability, biocompatibility, biomedical integration. Key innovations include flexible hybrid showing up 0.8 factors exceeding 500 μW/mK², ideal monitoring therapies. Despite progress, challenges remain high ZT, material stability, scalable production. Future efforts emphasize biocompatible materials, robust designs, seamless Thermoelectric can revolutionize personalized healthcare, enabling energy-autonomous reducing reliance conventional power. review highlights synergy between innovation technology next-generation applications.

Language: Английский

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Catalytic Nanozyme: Unlocking new horizons in articular cartilage degeneration treatment

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 541, P. 216845 - 216845

Published: May 29, 2025

Language: Английский

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