TEMPO-Mediated Electrochemical α-Allylation of Tetrahydroisoquinolines DOI

Youliang He,

Zhen‐Hua Wang,

Huilin Liu

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 25, 2025

A C(sp3)-H allylation of tetrahydroisoquinolines has been developed by combining Shono oxidation with a vinylogous Mannich-type reaction. TEMPO was used as the electrocatalyst to lower electrode potential, improving functional group compatibility. This method provided practical and efficient tandem procedure for α-allylation tetrahydroisoquinolines. The reaction proceeded through formation an iminium cation intermediate, which generated in situ anodic oxidation, followed nucleophilic addition 2-allylazaarenes.

Язык: Английский

Throwing Light on Synthetic Molecular Photoelectrocatalysis (Part II): selected recent transformations of organic compounds and a future perspective in organic synthesis DOI Creative Commons
Erick Steven Patiño-Alonzo, José Manuel Ramos-Villaseñor, Julio Romero‐Ibañez

и другие.

Current Opinion in Electrochemistry, Год журнала: 2025, Номер unknown, С. 101674 - 101674

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Photoelectrochemistry-Promoted Ni-Catalyzed C–O Cross-Couplings DOI Creative Commons

Zhao‐Ran Liu,

Ye Wang, Cong Ma

и другие.

Precision Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

Язык: Английский

Процитировано

0
TEMPO-Mediated Electrochemical α-Allylation of Tetrahydroisoquinolines DOI

Youliang He,

Zhen‐Hua Wang,

Huilin Liu

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 25, 2025

A C(sp3)-H allylation of tetrahydroisoquinolines has been developed by combining Shono oxidation with a vinylogous Mannich-type reaction. TEMPO was used as the electrocatalyst to lower electrode potential, improving functional group compatibility. This method provided practical and efficient tandem procedure for α-allylation tetrahydroisoquinolines. The reaction proceeded through formation an iminium cation intermediate, which generated in situ anodic oxidation, followed nucleophilic addition 2-allylazaarenes.

Язык: Английский

Процитировано

0