ACS Applied Nano Materials,
Год журнала:
2023,
Номер
6(17), С. 15530 - 15539
Опубликована: Авг. 29, 2023
Quaternary
ammonium
compounds
(QACs)
are
widely
used
in
disinfectants,
cleaners,
preservatives,
cosmetics,
and
agriculture.
Recently,
QACs
have
been
detected
the
human
bloodstream,
breast
milk,
neonatal
mouse
brain,
which
shows
that
these
can
cross
biological
barriers.
In
vivo
studies
showed
chronic
low-level
exposure
to
causes
developmental,
reproductive,
immune
dysfunctions,
whereas
vitro
indicate
affect
reproductive
systems,
disrupt
cholesterol
biosynthesis,
increase
inflammatory
cytokines,
decrease
mitochondrial
functions.
Effects
of
on
health
gradually
emerging,
amid
increased
use
QAC
disinfectants
during
COVID-19
pandemic.
Analysis
fluids
including
blood,
urine,
sweat,
saliva
provide
vital
information
determining
effects
analytes.
Biofluid
analysis
is
convenient
yet
crucial
because
non-invasive/or
minimally
invasive
procedures
be
performed
outside
hospital
settings.
Interest
optical
detection
methods
for
biofluid
has
growing
due
recent
advances
technologies
availability
tunable
materials
aid
technologies.
Detection
near-infrared
(NIR)
spectral
range
advantageous
over
visible
mainly
minimal
autofluorescence,
light-scattering,
absorption
from
native
molecules
NIR
range.
Photoluminescent
single-walled
carbon
nanotubes
(SWCNTs)
promising
candidates
development
probes
sensors
their
non-photobleaching
fluorescence,
surface
chemistry,
high
sensitivity.
Herein,
we
report
protein-rich
media
a
model
biofluid.
We
functionalized
photoluminescent
SWCNTs
with
bile
salt
derivatives
enabled
artificial
sweat
serum-protein-enriched
media.
The
was
significant
at
nanomolar
concentrations,
within
threshold
various
physiological
processes.
Thus,
nanotube-based
could
well
suited
fluids.
Environmental Science & Technology,
Год журнала:
2023,
Номер
57(9), С. 3804 - 3816
Опубликована: Фев. 22, 2023
Peroxides
find
broad
applications
for
disinfecting
environmental
pathogens
particularly
in
the
COVID-19
pandemic;
however,
extensive
use
of
chemical
disinfectants
can
threaten
human
health
and
ecosystems.
To
achieve
robust
sustainable
disinfection
with
minimal
adverse
impacts,
we
developed
Fe
single-atom
Fe–Fe
double-atom
catalysts
activating
peroxymonosulfate
(PMS).
The
catalyst
supported
on
sulfur-doped
graphitic
carbon
nitride
outperformed
other
oxidation,
it
activated
PMS
likely
through
a
nonradical
route
catalyst-mediated
electron
transfer.
This
enhanced
kinetics
inactivating
murine
coronaviruses
(i.e.,
hepatitis
virus
strain
A59
(MHV-A59))
by
2.17–4.60
times
when
compared
to
treatment
alone
diverse
media
including
simulated
saliva
freshwater.
molecular-level
mechanism
MHV-A59
inactivation
was
also
elucidated.
catalysis
promoted
damage
not
only
viral
proteins
genomes
but
internalization,
key
step
lifecycle
host
cells,
enhancing
potency
disinfection.
For
first
time,
our
study
advances
pathogen
control
provides
fundamental
insights
coronavirus
Our
work
paves
new
avenue
leveraging
advanced
materials
improving
disinfection,
sanitation,
hygiene
practices
protecting
public
health.
Chemosensors,
Год журнала:
2023,
Номер
11(2), С. 124 - 124
Опубликована: Фев. 7, 2023
Hydrogen
peroxide
(aqueous
solution
of
H2O2)
is
one
the
most
used
reagents
i
n
medical
sterilization,
environmental
disinfection,
food
storage,
and
other
fields.
However,
hydrogen
has
potential
to
cause
serious
harm
biological
health
safety.
There
are
many
methods
(especially
electrochemistry)
for
H2O2
detection
in
liquid
phase
systems,
but
a
lack
vapor
detection.
This
due
its
colorless
tasteless
nature,
as
well
oxidative
activity
molecule
coexistence
with
humidity.
In
this
study,
poly(3,4-ethylenedioxythiophene):polystyrene
sulfonate
(PEDOT:PSS),
commercially
successful
widely
conductive
polymers,
was
employed
fabricate
an
all-organic
chemiresistive
sensor
simple,
real-time,
on-site
sensing
(HPV)
at
room
temperature.
comparison
pristine
PEDOT:PSS
film,
PEDOT:PSS/PEDOT
film
prepared
by
situ
electrochemical
polymerization.
Upon
exposure
different
concentrations
HPV,
it
found
that
hydrophobic
porous
PEDOT
layer
could
weaken
interference
humidity
HPV
sensing,
resulting
more
sensitive
accurate
response.
At
1.0
ppm
concentration,
resistance
signal
response
increased
nearly
89%
compared
film.
PEDOT-film-based
showcases
possibility
further
development
nonenzymatic
monitoring
technology.
Biomolecules,
Год журнала:
2024,
Номер
14(8), С. 957 - 957
Опубликована: Авг. 7, 2024
The
adherence
of
pathogenic
microorganisms
to
surfaces
and
their
association
form
antibiotic-resistant
biofilms
threatens
public
health
affects
several
industrial
sectors
with
significant
economic
losses.
For
this
reason,
the
medical,
pharmaceutical
materials
science
communities
are
exploring
more
effective
anti-fouling
approaches.
This
review
focuses
on
properties,
structure-activity
relationships
environmental
toxicity
quaternary
ammonium
salts
(QAS)
and,
as
a
subclass,
ionic
liquid
compounds.
Greener
alternatives
such
QAS-based
antimicrobial
polymers
biocide
release,
non-fouling
(i.e.,
PEG,
zwitterions),
fouling
release
poly(dimethylsiloxanes),
fluorocarbon)
contact
killing
properties
highlighted.
We
also
report
dual-functional
stimuli-responsive
materials.
Given
impacts
in
submerged
surfaces,
we
emphasize
importance
less
explored
approaches
marine
industry
developing
efficient
membranes
for
water
treatment
systems.
Nanoscale,
Год журнала:
2024,
Номер
16(35), С. 16344 - 16375
Опубликована: Янв. 1, 2024
Single-walled
carbon
nanotubes
(SWCNTs)
possess
outstanding
photophysical
properties
which
has
garnered
interest
towards
utilizing
these
materials
for
biosensing
and
imaging
applications.
Antimicrobial Stewardship & Healthcare Epidemiology,
Год журнала:
2022,
Номер
2(1)
Опубликована: Янв. 1, 2022
Abstract
As
of
December
2021,
the
coronavirus
disease
2019
(COVID-19)
pandemic
has
claimed
millions
deaths
and
caused
disruptions
in
health
systems
around
world.
The
short-
long-term
effects
COVID-19
on
antimicrobial
resistance
(AMR),
which
was
already
a
global
threat
before
pandemic,
are
manifold
complex.
In
this
expert
review,
we
summarize
how
might
be
affecting
AMR
short
term
(by
influencing
key
determinants
antibiotic
use,
infection
control
practices
international/local
mobility)
additional
factors
play
role
long
term.
Whereas
reduced
outpatient
use
high-income
countries,
increased
awareness
for
hand
hygiene,
mobility
have
likely
mitigated
emergence
spread
term,
such
as
overuse
antibiotics
patients,
shortage
personal
protective
equipment,
lack
qualified
healthcare
staff,
patient
overcrowding
presumably
facilitated
its
propagation.
Unsurprisingly,
international
national
surveillance
data
2020
show
ambiguous
trends.
Although
stewardship
programs,
research
promote
AMR,
other
developments
could
prove
beneficial
to
cause
These
include
public
infectious
diseases
issues,
strengthening
One
Health
perspective
outlined
by
Centers
Disease
Control
Prevention,
unprecedented
number
collaborations
platforms.
even
serve
leverage
provide
opportunities
better
combat
future.
