Journal of Nanobiotechnology,
Год журнала:
2022,
Номер
20(1)
Опубликована: Март 24, 2022
Nowadays,
nano-/micro-motors
are
considered
as
powerful
tools
in
different
areas
ranging
from
cleaning
all
types
of
contaminants,
to
development
Targeted
drug
delivery
systems
and
diagnostic
activities.
Therefore,
the
application
based
on
metal-organic
frameworks
with
nanozyme
activity
(abbreviated
as:
MOF-NZs)
biomedical
activities
have
received
much
interest
recently.
after
investigating
catalytic
properties
applications
MOF-NZs
treatment
cancer,
this
study
intends
point
out
their
key
role
production
biocompatible
nano-/micro-motors.
Since
reducing
toxicity
MOF-NZ
can
pave
way
for
medical
activities,
article
examines
methods
making
nanomotors
address
benefits
drawbacks
required
propellants.
In
following,
an
analysis
amplified
directional
motion
under
physiological
conditions
is
presented,
which
improve
motor
behaviors
propulsion
function,
conductivity,
targeting,
release,
possible
elimination.
Meanwhile,
by
explaining
use
cancer
through
synergy
therapies,
it
was
revealed
that
be
effective
cancer.
Ultimately,
analyzing
potential
challenges
cancers,
we
hope
encourage
researchers
develop
MOF-NZs-based
nanomotors,
addition
opening
up
new
ideas
ongoing
problems.
Chemical Reviews,
Год журнала:
2021,
Номер
121(8), С. 4999 - 5041
Опубликована: Март 31, 2021
Manipulation
and
navigation
of
micro
nanoswimmers
in
different
fluid
environments
can
be
achieved
by
chemicals,
external
fields,
or
even
motile
cells.
Many
researchers
have
selected
magnetic
fields
as
the
active
actuation
source
based
on
advantageous
features
this
strategy
such
remote
spatiotemporal
control,
fuel-free,
high
degree
reconfigurability,
programmability,
recyclability,
versatility.
This
review
introduces
fundamental
concepts
advantages
micro/nanorobots
(termed
here
"MagRobots")
well
basic
knowledge
materials,
setups
for
manipulation,
field
configurations,
symmetry-breaking
strategies
effective
movement.
These
are
discussed
to
describe
interactions
between
fields.
Actuation
mechanisms
flagella-inspired
MagRobots
(i.e.,
corkscrew-like
motion
traveling-wave
locomotion/ciliary
stroke
motion)
surface
walkers
surface-assisted
motion),
applications
other
propulsion
approaches,
stimulation
beyond
provided
followed
fabrication
techniques
(quasi-)spherical,
helical,
flexible,
wire-like,
biohybrid
MagRobots.
Applications
targeted
drug/gene
delivery,
cell
minimally
invasive
surgery,
biopsy,
biofilm
disruption/eradication,
imaging-guided
delivery/therapy/surgery,
pollution
removal
environmental
remediation,
(bio)sensing
also
reviewed.
Finally,
current
challenges
future
perspectives
development
magnetically
powered
miniaturized
motors
discussed.
Journal of the American Chemical Society,
Год журнала:
2021,
Номер
143(15), С. 5569 - 5591
Опубликована: Апрель 8, 2021
Pumps
and
motors
are
essential
components
of
the
world
as
we
know
it.
From
complex
proteins
that
sustain
our
cells,
to
mechanical
marvels
power
industries,
much
take
for
granted
is
only
possible
because
pumps
motors.
Although
molecular
have
supported
life
eons,
it
recently
chemists
made
progress
toward
designing
building
artificial
forms
microscopic
machinery
present
in
nature.
The
advent
machines
has
scientists
an
unprecedented
level
control
over
relative
motion
molecules
through
development
kinetically
controlled,
away-from-thermodynamic
equilibrium
chemistry.
We
outline
history
motors,
focusing
specifically
on
innovations
enable
design
synthesis
central
this
Perspective.
A
key
insight
connecting
biomolecular
physical
motions
by
which
these
carry
out
their
function
unambiguously
at
every
instant.
operation
can
be
described
trajectory
thermodynamics,
a
theory
based
work
Onsager,
grounded
firm
foundation
principle
reversibility.
Free
energy
derived
from
thermodynamically
non-equilibrium
reactions
favors
some
reaction
pathways
others.
By
with
kinetic
asymmetry,
one
engineer
potential
landscapes
harness
external
drive
formation
maintenance
geometries
component
parts
away-from-equilibrium,
would
impossible
achieve
standard
synthetic
approaches.
Advances in Colloid and Interface Science,
Год журнала:
2023,
Номер
314, С. 102864 - 102864
Опубликована: Фев. 26, 2023
Designable
morphology
and
predictable
properties
are
the
most
challenging
goals
in
material
engineering.
Features
such
as
shape,
size,
porosity,
agglomeration
ratio
significantly
affect
final
of
metal-organic
frameworks
(MOFs)
can
be
regulated
throughout
synthesis
parameters
but
require
a
deep
understanding
mechanisms
MOFs
formation.
Herein,
we
systematically
summarize
effects
individual
factors,
pH
reaction
mixture,
including
acidic
or
basic
character
modulators,
temperature,
solvents
types,
surfactants
type
content
ionic
liquids
on
growing
MOFs.
We
identified
main
MOFs'
growth
leading
to
different
particles
next
discuss
effect
miscellaneous
based
related
nucleation,
formation
structure,
coordination
modulation,
protonation/deprotonation
acting
modulation
by
capping
agents.
The
microwaves
ultrasound
employment
during
is
also
considered
due
their
affecting
especially
nucleation
steps
Abstract
Ubiquitous
pollution
by
microplastics
is
causing
significant
deleterious
effects
on
marine
life
and
human
health
through
the
food
chain
has
become
a
big
challenge
for
global
ecosystem.
It
of
great
urgency
to
find
cost‐efficient
biocompatible
material
remove
from
environment.
Mimicking
basic
characteristics
adhesive
chemistry
practiced
mussels,
polydopamine
(PDA)@Fe
3
O
4
magnetic
microrobots
(MagRobots)
are
prepared
coating
Fe
nanoparticles
with
polymeric
layer
dopamine
via
one‐step
self‐polymerization.
In
addition,
lipase
loaded
PDA@Fe
MagRobots’
surface
perform
microplastic
enzymatic
degradation.
The
synthesized
MagRobots,
which
externally
triggered
transversal
rotating
field,
have
capacity
clear
away
targeted
due
their
strong
sticky
characteristics.
With
MagRobots
surfaces,
can
be
navigated
along
an
arbitrarily
predefined
path
field
removed
using
directional
field.
Such
envisioned
used
in
swarms
aqueous
environments.
Chemical Reviews,
Год журнала:
2022,
Номер
123(7), С. 3944 - 3975
Опубликована: Сен. 15, 2022
Micro-/nanorobots
(MNRs)
can
be
autonomously
propelled
on
demand
in
complex
biological
environments
and
thus
may
bring
revolutionary
changes
to
biomedicines.
Fluorescence
has
been
widely
used
real-time
imaging,
chemo-/biosensing,
photo-(chemo-)
therapy.
The
integration
of
MNRs
with
fluorescence
generates
fluorescent
unique
advantages
optical
trackability,
on-the-fly
environmental
sensitivity,
targeting
chemo-/photon-induced
cytotoxicity.
This
review
provides
an
up-to-date
overview
MNRs.
After
the
highlighted
elucidation
about
various
propulsion
mechanisms
introductory
information
emphasis
materials,
we
systematically
illustrate
design
preparation
strategies
integrate
substances
their
biomedical
applications
imaging-guided
drug
delivery,
intelligent
sensing
In
end,
summarize
main
challenges
provide
outlook
future
directions
work
is
expected
attract
inspire
researchers
from
different
communities
advance
creation
practical
application
a
broad
horizon.
Proceedings of the IEEE,
Год журнала:
2022,
Номер
110(7), С. 1028 - 1037
Опубликована: Апрель 28, 2022
The
use
of
magnetic
fields
and
field
gradients
to
move
material
devices
within
the
human
body
has
a
surprisingly
long
history.
Over
past
two
decades,
there
been
renewed
interest
in
this
area
with
growth
medical
microrobots.
In
article,
we
focus
on
state-of-the-art
future
directions
for
magnetically
actuated
robots
from
an
in
vivo
perspective.
We
initially
review
history
relevant
physics
followed
by
discussion
limited
research
efforts
that
investigate
guided
devices.
Our
is
tethered
probes,
untethered
(microrobots
nanorobots),
navigation
systems
have
or
could
be
utilized
provide
increased
control
safety
physician
patient.
Nature Communications,
Год журнала:
2023,
Номер
14(1)
Опубликована: Сен. 21, 2023
The
intricate
and
delicate
anatomy
of
the
brain
poses
significant
challenges
for
treatment
cerebrovascular
neurodegenerative
diseases.
Thus,
precise
local
drug
delivery
in
hard-to-reach
regions
remains
an
urgent
medical
need.
Microrobots
offer
potential
solutions;
however,
their
functionality
restricted
by
limited
imaging
capabilities
complications
within
blood
vessels,
such
as
high
flows,
osmotic
pressures,
cellular
responses.
Here,
we
introduce
ultrasound-activated
microrobots
vivo
navigation
vasculature.
Our
consist
lipid-shelled
microbubbles
that
autonomously
aggregate
propel
under
ultrasound
irradiation.
We
investigate
capacities
vitro
microfluidic-based
vasculatures
vessels
a
living
mouse
brain.
These
self-assemble
execute
upstream
motion
vasculature,
achieving
velocities
up
to
1.5
µm/s
moving
against
flows
~10
mm/s.
This
work
represents
substantial
advance
towards
therapeutic
application
complex
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(18), С. 9190 - 9253
Опубликована: Янв. 1, 2024
Autonomous
micro/nanorobots
capable
of
performing
programmed
missions
are
at
the
forefront
next-generation
micromachinery.
These
small
robotic
systems
predominantly
constructed
using
functional
components
sourced
from
micro-
and
nanoscale
materials;
therefore,
combining
them
with
various
advanced
materials
represents
a
pivotal
direction
toward
achieving
higher
level
intelligence
multifunctionality.
This
review
provides
comprehensive
overview
for
innovative
micro/nanorobotics,
focusing
on
five
families
that
have
witnessed
most
rapid
advancements
over
last
decade:
two-dimensional
materials,
metal-organic
frameworks,
semiconductors,
polymers,
biological
cells.
Their
unique
physicochemical,
mechanical,
optical,
properties
been
integrated
into
to
achieve
greater
maneuverability,
programmability,
intelligence,
multifunctionality
in
collective
behaviors.
The
design
fabrication
methods
hybrid
discussed
based
material
categories.
In
addition,
their
promising
potential
powering
motion
and/or
(multi-)functionality
is
described
fundamental
principles
underlying
explained.
Finally,
extensive
use
variety
applications,
including
environmental
remediation,
(bio)sensing,
therapeutics,
