Food Hydrocolloids, Год журнала: 2023, Номер 150, С. 109668 - 109668
Опубликована: Дек. 19, 2023
Язык: Английский
Chemical Reviews, Год журнала: 2021, Номер 121(8), С. 4999 - 5041
Опубликована: Март 31, 2021
Manipulation and navigation of micro nanoswimmers in different fluid environments can be achieved by chemicals, external fields, or even motile cells. Many researchers have selected magnetic fields as the active actuation source based on advantageous features this strategy such remote spatiotemporal control, fuel-free, high degree reconfigurability, programmability, recyclability, versatility. This review introduces fundamental concepts advantages micro/nanorobots (termed here "MagRobots") well basic knowledge materials, setups for manipulation, field configurations, symmetry-breaking strategies effective movement. These are discussed to describe interactions between fields. Actuation mechanisms flagella-inspired MagRobots (i.e., corkscrew-like motion traveling-wave locomotion/ciliary stroke motion) surface walkers surface-assisted motion), applications other propulsion approaches, stimulation beyond provided followed fabrication techniques (quasi-)spherical, helical, flexible, wire-like, biohybrid MagRobots. Applications targeted drug/gene delivery, cell minimally invasive surgery, biopsy, biofilm disruption/eradication, imaging-guided delivery/therapy/surgery, pollution removal environmental remediation, (bio)sensing also reviewed. Finally, current challenges future perspectives development magnetically powered miniaturized motors discussed.
Язык: Английский
Процитировано
576
Journal of the American Chemical Society, Год журнала: 2021, Номер 143(15), С. 5569 - 5591
Опубликована: Апрель 8, 2021
Pumps and motors are essential components of the world as we know it. From complex proteins that sustain our cells, to mechanical marvels power industries, much take for granted is only possible because pumps motors. Although molecular have supported life eons, it recently chemists made progress toward designing building artificial forms microscopic machinery present in nature. The advent machines has scientists an unprecedented level control over relative motion molecules through development kinetically controlled, away-from-thermodynamic equilibrium chemistry. We outline history motors, focusing specifically on innovations enable design synthesis central this Perspective. A key insight connecting biomolecular physical motions by which these carry out their function unambiguously at every instant. operation can be described trajectory thermodynamics, a theory based work Onsager, grounded firm foundation principle reversibility. Free energy derived from thermodynamically non-equilibrium reactions favors some reaction pathways others. By with kinetic asymmetry, one engineer potential landscapes harness external drive formation maintenance geometries component parts away-from-equilibrium, would impossible achieve standard synthetic approaches.
Язык: Английский
Процитировано
200
Trends in Food Science & Technology, Год журнала: 2021, Номер 109, С. 413 - 434
Опубликована: Янв. 12, 2021
Язык: Английский
Процитировано
191
Advances in Colloid and Interface Science, Год журнала: 2023, Номер 314, С. 102864 - 102864
Опубликована: Фев. 26, 2023
Designable morphology and predictable properties are the most challenging goals in material engineering. Features such as shape, size, porosity, agglomeration ratio significantly affect final of metal-organic frameworks (MOFs) can be regulated throughout synthesis parameters but require a deep understanding mechanisms MOFs formation. Herein, we systematically summarize effects individual factors, pH reaction mixture, including acidic or basic character modulators, temperature, solvents types, surfactants type content ionic liquids on growing MOFs. We identified main MOFs' growth leading to different particles next discuss effect miscellaneous based related nucleation, formation structure, coordination modulation, protonation/deprotonation acting modulation by capping agents. The microwaves ultrasound employment during is also considered due their affecting especially nucleation steps
Язык: Английский
Процитировано
146
Small Methods, Год журнала: 2021, Номер 5(9)
Опубликована: Авг. 15, 2021
Abstract Ubiquitous pollution by microplastics is causing significant deleterious effects on marine life and human health through the food chain has become a big challenge for global ecosystem. It of great urgency to find cost‐efficient biocompatible material remove from environment. Mimicking basic characteristics adhesive chemistry practiced mussels, polydopamine (PDA)@Fe 3 O 4 magnetic microrobots (MagRobots) are prepared coating Fe nanoparticles with polymeric layer dopamine via one‐step self‐polymerization. In addition, lipase loaded PDA@Fe MagRobots’ surface perform microplastic enzymatic degradation. The synthesized MagRobots, which externally triggered transversal rotating field, have capacity clear away targeted due their strong sticky characteristics. With MagRobots surfaces, can be navigated along an arbitrarily predefined path field removed using directional field. Such envisioned used in swarms aqueous environments.
Язык: Английский
Процитировано
110
Chemical Reviews, Год журнала: 2022, Номер 123(7), С. 3944 - 3975
Опубликована: Сен. 15, 2022
Micro-/nanorobots (MNRs) can be autonomously propelled on demand in complex biological environments and thus may bring revolutionary changes to biomedicines. Fluorescence has been widely used real-time imaging, chemo-/biosensing, photo-(chemo-) therapy. The integration of MNRs with fluorescence generates fluorescent unique advantages optical trackability, on-the-fly environmental sensitivity, targeting chemo-/photon-induced cytotoxicity. This review provides an up-to-date overview MNRs. After the highlighted elucidation about various propulsion mechanisms introductory information emphasis materials, we systematically illustrate design preparation strategies integrate substances their biomedical applications imaging-guided drug delivery, intelligent sensing In end, summarize main challenges provide outlook future directions work is expected attract inspire researchers from different communities advance creation practical application a broad horizon.
Язык: Английский
Процитировано
86
Proceedings of the IEEE, Год журнала: 2022, Номер 110(7), С. 1028 - 1037
Опубликована: Апрель 28, 2022
The
use
of
magnetic
fields
and
field
gradients
to
move
material
devices
within
the
human
body
has
a
surprisingly
long
history.
Over
past
two
decades,
there
been
renewed
interest
in
this
area
with
growth
medical
microrobots.
In
article,
we
focus
on
state-of-the-art
future
directions
for
magnetically
actuated
robots
from
an
Язык: Английский
Процитировано
72
Nature Communications, Год журнала: 2023, Номер 14(1)
Опубликована: Сен. 21, 2023
The intricate and delicate anatomy of the brain poses significant challenges for treatment cerebrovascular neurodegenerative diseases. Thus, precise local drug delivery in hard-to-reach regions remains an urgent medical need. Microrobots offer potential solutions; however, their functionality restricted by limited imaging capabilities complications within blood vessels, such as high flows, osmotic pressures, cellular responses. Here, we introduce ultrasound-activated microrobots vivo navigation vasculature. Our consist lipid-shelled microbubbles that autonomously aggregate propel under ultrasound irradiation. We investigate capacities vitro microfluidic-based vasculatures vessels a living mouse brain. These self-assemble execute upstream motion vasculature, achieving velocities up to 1.5 µm/s moving against flows ~10 mm/s. This work represents substantial advance towards therapeutic application complex
Язык: Английский
Процитировано
54
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 261, С. 129799 - 129799
Опубликована: Фев. 1, 2024
Язык: Английский
Процитировано
23
Chemical Society Reviews, Год журнала: 2024, Номер 53(18), С. 9190 - 9253
Опубликована: Янв. 1, 2024
Autonomous micro/nanorobots capable of performing programmed missions are at the forefront next-generation micromachinery. These small robotic systems predominantly constructed using functional components sourced from micro- and nanoscale materials; therefore, combining them with various advanced materials represents a pivotal direction toward achieving higher level intelligence multifunctionality. This review provides comprehensive overview for innovative micro/nanorobotics, focusing on five families that have witnessed most rapid advancements over last decade: two-dimensional materials, metal-organic frameworks, semiconductors, polymers, biological cells. Their unique physicochemical, mechanical, optical, properties been integrated into to achieve greater maneuverability, programmability, intelligence, multifunctionality in collective behaviors. The design fabrication methods hybrid discussed based material categories. In addition, their promising potential powering motion and/or (multi-)functionality is described fundamental principles underlying explained. Finally, extensive use variety applications, including environmental remediation, (bio)sensing, therapeutics,
Язык: Английский
Процитировано
20