ACS ES&T Water, Год журнала: 2024, Номер 4(9), С. 3614 - 3618
Опубликована: Авг. 13, 2024
Язык: Английский
Frontiers in Immunology, Год журнала: 2023, Номер 14
Опубликована: Апрель 18, 2023
Gastric cancer is one of the top causes cancer-related death globally. Although novel treatment strategies have been developed, attempts to eradicate gastric proven insufficient. Oxidative stress continually produced and present in human body. Increasing evidences show that oxidative contributes significantly development cancer, either through initiation, promotion, progression cells or causing cell death. As a result, purpose this article review role response subsequent signaling pathways as well potential stress-related therapeutic targets cancer. Understanding pathophysiology developing new therapies for depends on more researches focusing contributors carcinogenesis.
Язык: Английский
Процитировано
33
Environment International, Год журнала: 2024, Номер 187, С. 108724 - 108724
Опубликована: Май 1, 2024
The mass concentration of atmospheric particulate matter (PM) has been continuously decreasing in the Beijing-Tianjin-Hebei region. However, health endpoints do not exhibit a linear correlation with PM concentrations. Thus, it is urgent to clarify prior toxicological components further improve air quality. In this study, we analyzed long-term oxidative potential (OP) water-soluble PM2.5, which generally considered more effective assessing hazardous exposure Beijing from 2018 2022 based on dithiothreitol assay and identified crucial drivers OP PM2.5 online monitoring pollutants, receptor model, random forest (RF) model. Our results indicate that dust, traffic, biomass combustion are main sources Beijing. complex interactions dust particles, black carbon, gaseous pollutants (nitrogen dioxide sulfur dioxide) factors driving evolution, particular, leading abnormal rise 2022. data shows higher observed winter spring compared summer autumn. diurnal variation characterized by declining trend 0:00 14:00 an increasing 23:00. spatial was as lower than Shijiazhuang, while Zhenjiang Haikou, primarily influenced distribution carbon. significance identifying key influencing provide new insights for advancing quality improvement efforts focus safeguarding human
Язык: Английский
Процитировано
10
Current Pollution Reports, Год журнала: 2023, Номер 9(3), С. 590 - 601
Опубликована: Июнь 16, 2023
Язык: Английский
Процитировано
19
Chemical Research in Chinese Universities, Год журнала: 2023, Номер 39(3), С. 326 - 341
Опубликована: Апрель 29, 2023
Язык: Английский
Процитировано
14
ACS ES&T Air, Год журнала: 2024, Номер 1(4), С. 273 - 282
Опубликована: Фев. 21, 2024
Biomass burning brown carbon (BrC) aerosol affects the climate by absorbing light in visible and UV wavelengths, with daytime photochemistry changing its optical properties. Here, aging UVB irradiation of BrC both aqueous particle states was conducted to evaluate conditions mechanism required change ability absorb an emphasis on role radicals oxidation. Photoreactions enhanced absorption O2 present phase particulate states. Deoxygenated samples did not show this enhancement, indicating importance oxidation mechanism. Using furfuryl alcohol as a singlet oxygen (1O2) scavenger, it shown that 1O2 contributes roughly one third increase phase. Conversely, hydroxyl (OH) were demonstrated have no impact. Carbon-centered radicals, measured electron paramagnetic resonance state, formed when but for deoxygenated irradiation. Overall, dependence indicates highly viscous particles, will be atmosphere at low temperatures and/or relative humidity, may experience same degree photochemical more liquid-like particles.
Язык: Английский
Процитировано
5
Environment International, Год журнала: 2024, Номер 193, С. 109102 - 109102
Опубликована: Окт. 28, 2024
Язык: Английский
Процитировано
4
ACS ES&T Air, Год журнала: 2025, Номер unknown
Опубликована: Янв. 28, 2025
Язык: Английский
Процитировано
0
Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 138139 - 138139
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Aerosol Research, Год журнала: 2025, Номер 3(1), С. 205 - 218
Опубликована: Апрель 22, 2025
Abstract. Air pollution is one of the largest environmental health risks and leading causes adverse outcomes mortality worldwide. The possible importance oxidative potential (OP) as a metric to quantify particle toxicity in air increasingly being recognised. In this work, OP reactive oxygen species (ROS) activity particles from fresh aged petrol passenger car emissions residential wood combustion (RWC) were investigated using two novel instruments. Applying online instruments an ascorbic acid (AA) 2′,7′-dichlorodihydrofluorescein (DCFH) assay provides much higher temporal resolution compared with traditional filter-based methods allows for new insights into highly dynamic changes ROS these sources. Due efficiency particulate filter Euro 6d car, almost no primary emitted and, thus, or was detected exhaust. However, substantial ROSs observed after photochemical ageing due formation secondary particles. Increasing also when comparing RWC emissions. Overall, had signals This suggests that could be major contributor may intrinsically more harmful emission source than exhaust, although still high. These measurements illustrate strong differences nature toxicity-relevant properties sources contribute efficient mitigation policies.
Язык: Английский
Процитировано
0
The Science of The Total Environment, Год журнала: 2023, Номер 895, С. 165180 - 165180
Опубликована: Июнь 27, 2023
Язык: Английский
Процитировано
9