Experimental factors influencing the bioaccessibility and the oxidative potential of transition metals from welding fumes DOI
Manuella Ghanem, L. Alleman, Davy Rousset

et al.

Environmental Science Processes & Impacts, Journal Year: 2024, Volume and Issue: 26(5), P. 843 - 857

Published: Jan. 1, 2024

Experimental conditions such as extraction methods and storage induce biases on the measurement of oxidative potential bioaccessibility transition metals from welding fumes.

Language: Английский

Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer DOI Creative Commons
Yingying Liu, Yu Shi, Ruiqin Han

et al.

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14

Published: April 18, 2023

Gastric cancer is one of the top causes cancer-related death globally. Although novel treatment strategies have been developed, attempts to eradicate gastric proven insufficient. Oxidative stress continually produced and present in human body. Increasing evidences show that oxidative contributes significantly development cancer, either through initiation, promotion, progression cells or causing cell death. As a result, purpose this article review role response subsequent signaling pathways as well potential stress-related therapeutic targets cancer. Understanding pathophysiology developing new therapies for depends on more researches focusing contributors carcinogenesis.

Language: Английский

Citations

35
Key drivers of the oxidative potential of PM2.5 in Beijing in the context of air quality improvement from 2018 to 2022 DOI Creative Commons
Jinwen Li,

Chenjie Hua,

Li Ma

et al.

Environment International, Journal Year: 2024, Volume and Issue: 187, P. 108724 - 108724

Published: May 1, 2024

The mass concentration of atmospheric particulate matter (PM) has been continuously decreasing in the Beijing-Tianjin-Hebei region. However, health endpoints do not exhibit a linear correlation with PM concentrations. Thus, it is urgent to clarify prior toxicological components further improve air quality. In this study, we analyzed long-term oxidative potential (OP) water-soluble PM2.5, which generally considered more effective assessing hazardous exposure Beijing from 2018 2022 based on dithiothreitol assay and identified crucial drivers OP PM2.5 online monitoring pollutants, receptor model, random forest (RF) model. Our results indicate that dust, traffic, biomass combustion are main sources Beijing. complex interactions dust particles, black carbon, gaseous pollutants (nitrogen dioxide sulfur dioxide) factors driving evolution, particular, leading abnormal rise 2022. data shows higher observed winter spring compared summer autumn. diurnal variation characterized by declining trend 0:00 14:00 an increasing 23:00. spatial was as lower than Shijiazhuang, while Zhenjiang Haikou, primarily influenced distribution carbon. significance identifying key influencing provide new insights for advancing quality improvement efforts focus safeguarding human

Language: Английский

Citations

12
Aging Effects on the Toxicity Alteration of Different Types of Organic Aerosols: A Review DOI

Ruoyuan Lei,

Ziqian Wei, Meijuan Chen

et al.

Current Pollution Reports, Journal Year: 2023, Volume and Issue: 9(3), P. 590 - 601

Published: June 16, 2023

Language: Английский

Citations

19
Toxicological Effects of Secondary Air Pollutants DOI Open Access

Wang Xiang,

Weigang Wang, Libo Du

et al.

Chemical Research in Chinese Universities, Journal Year: 2023, Volume and Issue: 39(3), P. 326 - 341

Published: April 29, 2023

Language: Английский

Citations

18
Light Exposure of Wood Smoke Aerosol: Connecting Optical Properties, Oxidation, Radical Formation, and Chemical Composition DOI
Carolyn Liu-Kang, Anna Sokolova, Yufeng Gong

et al.

ACS ES&T Air, Journal Year: 2024, Volume and Issue: 1(4), P. 273 - 282

Published: Feb. 21, 2024

Biomass burning brown carbon (BrC) aerosol affects the climate by absorbing light in visible and UV wavelengths, with daytime photochemistry changing its optical properties. Here, aging UVB irradiation of BrC both aqueous particle states was conducted to evaluate conditions mechanism required change ability absorb an emphasis on role radicals oxidation. Photoreactions enhanced absorption O2 present phase particulate states. Deoxygenated samples did not show this enhancement, indicating importance oxidation mechanism. Using furfuryl alcohol as a singlet oxygen (1O2) scavenger, it shown that 1O2 contributes roughly one third increase phase. Conversely, hydroxyl (OH) were demonstrated have no impact. Carbon-centered radicals, measured electron paramagnetic resonance state, formed when but for deoxygenated irradiation. Overall, dependence indicates highly viscous particles, will be atmosphere at low temperatures and/or relative humidity, may experience same degree photochemical more liquid-like particles.

Language: Английский

Citations

5
High time resolution quantification of PM2.5 oxidative potential at a Central London Roadside Supersite DOI Creative Commons
Steven J. Campbell, Alexandre Barth, Gang Chen

et al.

Environment International, Journal Year: 2024, Volume and Issue: 193, P. 109102 - 109102

Published: Oct. 28, 2024

Language: Английский

Citations

5
Water-soluble organic carbon (WSOC) from vegetation fire and its differences from WSOC in natural media: Spectral comparison and self-organizing maps (SOM) classification DOI
Huiying Zhang, Jinzhi Ni, Ran Wei

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 895, P. 165180 - 165180

Published: June 27, 2023

Language: Английский

Citations

9
Formation of Ozone and PM2.5 in Smoke from Prescribed Burning in the Southeastern United States DOI Creative Commons

Rime El Asmar,

Zongrun Li, Haofei Yu

et al.

ACS ES&T Air, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Language: Английский

Citations

0
Key Toxicity Enhancement Effect of Aqueous-Phase Secondary Formation: Insights from Hourly Measurements during Haze Events DOI

Feiyan Cao,

Yingjun Chen,

Yong Han

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 138139 - 138139

Published: April 1, 2025

Language: Английский

Citations

0
Emission dynamics of reactive oxygen species and oxidative potential in particles from a petrol car and wood stove DOI Creative Commons
Battist Utinger, Alexandre Barth, Andreas Paul

et al.

Aerosol Research, Journal Year: 2025, Volume and Issue: 3(1), P. 205 - 218

Published: April 22, 2025

Abstract. Air pollution is one of the largest environmental health risks and leading causes adverse outcomes mortality worldwide. The possible importance oxidative potential (OP) as a metric to quantify particle toxicity in air increasingly being recognised. In this work, OP reactive oxygen species (ROS) activity particles from fresh aged petrol passenger car emissions residential wood combustion (RWC) were investigated using two novel instruments. Applying online instruments an ascorbic acid (AA) 2′,7′-dichlorodihydrofluorescein (DCFH) assay provides much higher temporal resolution compared with traditional filter-based methods allows for new insights into highly dynamic changes ROS these sources. Due efficiency particulate filter Euro 6d car, almost no primary emitted and, thus, or was detected exhaust. However, substantial ROSs observed after photochemical ageing due formation secondary particles. Increasing also when comparing RWC emissions. Overall, had signals This suggests that could be major contributor may intrinsically more harmful emission source than exhaust, although still high. These measurements illustrate strong differences nature toxicity-relevant properties sources contribute efficient mitigation policies.

Language: Английский

Citations

0