Mutation Research/Genetic Toxicology and Environmental Mutagenesis,
Год журнала:
2023,
Номер
892, С. 503705 - 503705
Опубликована: Окт. 10, 2023
The
ubiquitous
pollution
of
plastic
particles
in
most
environmental
matrices
leads
to
concern
about
any
potential
adverse
effects
on
human
health.
Most
studies
the
toxicological
effect
nanoplastics
has
focused
standard
polystyrene.
In
reality
humans
are
exposed
a
large
variety
different
types
and
sizes
material
via
oral
intake
inhalation.
this
study,
we
investigated
polyethylene
terephthalate
(PET)
nanoplastic
from
ground
food
containers
supermarket.
aim
was
investigate
possible
link
between
exposure
PET
genotoxic
response
cell
model
airway
epithelial
(A549)
cells.
Further,
combined
chemicals
known
alter
cellular
redox
state,
as
partially
compromised
antioxidant
defense
system.
DNA
damage
assessed
by
alkaline
comet
assay.
have
mean
hydrodynamic
diameter
136
nm
water.
results
showed
that
led
increased
reactive
oxygen
species
production
(approximately
30
%
increase
compared
unexposed
cells).
addition,
level
strand
breaks
(net
=
0.10
lesions/106
base
pair,
95
confidence
interval:
0.01,
0.18
pair).
Pre-
or
post-exposure
hydrogen
peroxide
buthionine
sulfoximine
did
not
lead
higher
damage.
Overall,
study
shows
increases
both
intracellular
A549
Advanced Functional Materials,
Год журнала:
2023,
Номер
34(2)
Опубликована: Сен. 10, 2023
Abstract
Microplastics
(MPs)
are
present
not
only
in
the
environment
but
also
drinking
water,
food,
and
consumer
products.
These
MPs
being
toxic,
carcinogenic,
endocrine
disrupting,
genetic
risk
creators
cause
several
diseases.
Despite
various
approaches,
development
of
onsite
applicable,
facile,
quick
MP
detection
methods
is
still
challenging.
Here,
3D‐plasmonic
gold
nanopocket
(3D‐PGNP)
nanoarchitecture
formed
on
a
paper
substrate
for
simultaneous
filtration
detection.
The
paper‐based
3D‐PGNP
integrated
with
syringe
filter
device,
then,
MP‐containing
solutions
injected
through
syringe.
Subsequent
using
surface‐enhanced
Raman
scattering
(SERS)
successfully
identifies
without
pretreatment.
interface
volumetric
hotspot
generation
around
captured
significantly
improves
sensitivity,
which
confirmed
by
finite‐difference
time‐domain
simulation.
Then,
SERS
mapping
images
obtained
from
portable
spectrometer
transformed
into
digital
signals
via
machine
learning
(ML)
technique
to
identify
quantify
distribution.
developed
SERS‐ML‐based
method
applied
mixture
real
matrix
samples,
demonstrating
that
provides
improved
accuracy.
This
system
expected
be
used
environmentally
hazardous
substances,
such
as
bacteria,
viruses,
fungi.
Environmental Science & Technology,
Год журнала:
2024,
Номер
unknown
Опубликована: Фев. 5, 2024
The
increasing
global
attention
on
micro(nano)plastics
(MNPs)
is
a
result
of
their
ubiquity
in
the
water,
air,
soil,
and
biosphere,
exposing
humans
to
MNPs
daily
basis
threatening
human
health.
However,
crucial
data
body,
including
sources,
occurrences,
behaviors,
health
risks,
are
limited,
which
greatly
impedes
any
systematic
assessment
impact
body.
To
further
understand
effects
we
must
identify
existing
knowledge
gaps
that
need
be
immediately
addressed
provide
potential
solutions
these
issues.
Herein,
examined
current
literature
behaviors
body
as
well
risks.
Furthermore,
identified
key
resolved
comprehensively
assess
Additionally,
complexity
lack
efficient
analytical
methods
main
barriers
impeding
investigations
necessitating
development
standard
unified
method.
Finally,
highlighted
for
interdisciplinary
studies
from
environmental,
biological,
medical,
chemical,
computer,
material
scientists
fill
drive
research.
Considering
inevitability
occurrence
exposure
MNPs,
more
urgently
required
enhance
our
understanding
negative
Environmental Sciences Europe,
Год журнала:
2025,
Номер
37(1)
Опубликована: Янв. 8, 2025
The
degradation
of
mismanaged
plastic
waste
in
the
environment
results
formation
microplastics
(MPs)
and
nanoplastics
(NPs),
which
pose
significant
risks
to
ecosystems
human
health.
These
particles
are
pervasive,
detected
even
remote
regions,
can
enter
food
chain,
accumulating
organisms
causing
harm
depending
on
factors
such
as
particle
load,
exposure
dose,
presence
co-contaminants.
Detecting
analyzing
NMPs
present
unique
challenges,
particularly
size
decreases,
making
them
increasingly
difficult
identify.
Moreover,
absence
standardized
protocols
for
their
detection
analysis
further
hinders
comprehensive
assessments
environmental
biological
impacts.
This
review
provides
a
detailed
overview
latest
advancements
technologies
sampling,
separation,
measurement,
quantification
NMPs.
It
highlights
promising
approaches,
supported
by
practical
examples
from
recent
studies,
while
critically
addressing
persistent
challenges
characterization,
analysis.
work
examines
cutting-edge
developments
nanotechnology-based
detection,
integrated
spectro-microscopic
techniques,
AI-driven
classification
algorithms,
offering
solutions
bridge
gaps
NMP
research.
By
exploring
state-of-the-art
methodologies
presenting
future
perspectives,
this
valuable
insights
improving
capabilities
at
micro-
nanoscale,
enabling
more
effective
across
diverse
contexts.
Analytical Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 23, 2025
Nanoplastics,
emerging
as
pervasive
environmental
pollutants,
pose
significant
threats
to
ecosystems
and
human
health
due
their
small
size
potential
toxicity.
However,
detecting
trace
levels
of
nanoplastics
remains
challenging
because
limitations
in
the
current
analytical
methods.
Herein,
we
propose
a
method
that
combines
superhydrophobic
enrichment
with
SERS
analysis
for
aqueous
environments.
Superhydrophobic
substrates
were
prepared
by
using
liquid-liquid
self-assembly
method.
The
superhydrophobicity
facilitated
analyte
enrichment,
monolayer
Au
nanoparticles
(AuNPs)
enhanced
Raman
signals.
detection
limit
probe
crystal
violet
(CV)
this
substrate
reached
nanomolar
(10-9
M),
an
RSD
9.96%
across
40
×
μm2
area
(441
spots),
demonstrating
excellent
sensitivity
reproducibility.
This
successfully
detected
polystyrene
(PS)
plastics
ranging
from
30
1000
nm
water
concentrations
low
0.03
μg/mL.
Additionally,
nanoscale
polyethylene
terephthalate
(PET)
particles
bottled
samples.
approach
offers
promising
platform
analyzing
samples
addresses
needs
monitoring.
ACS Nano,
Год журнала:
2024,
Номер
18(3), С. 2370 - 2383
Опубликована: Янв. 8, 2024
Nanoplastics
(NPs)
pervade
daily
life,
posing
serious
threats
to
marine
ecosystems.
Despite
the
crucial
role
that
surface
charge
plays
in
NP
effects,
there
is
a
substantial
gap
our
understanding
of
how
influences
toxicity.
Herein,
by
exposing
