Organ-Specific Effects of Polystyrene Nanoplastics on Deltamethrin-Induced Toxicity in Mice: Mitigated Hepatorenal Oxidative Damage But Increased Enteric Toxicity DOI
Mengyuan Qi, Shengdong Zhang, Hua Fang

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер 73(9), С. 5092 - 5101

Опубликована: Фев. 24, 2025

This study investigates the combined effects of polystyrene nanoplastics (PS-NPs) and deltamethrin (DEL) on mice, focusing their different impacts among organs. Mice were exposed to PS-NPs and/or DEL for 30 days. Results showed that alleviated DEL-induced oxidative damage in liver kidney by reducing its accumulation due decreased bioaccessibility. Conversely, increased intestine, leading enhanced susceptibility enteric infections caused bacteria, viruses, parasites, as indicated transcriptomic analysis. delayed excretion gastrointestinal motility, evidenced altered neurotransmitter levels, thereby contributing greater intestinal DEL. Moreover, 16S rDNA sequencing revealed tended decrease beneficial bacteria increase pathogenic gut microbiota, further heightening upon coexposure. The findings this shed new light complex health risks associated with coexposure pesticides.

Язык: Английский

Twenty years of microplastics pollution research—what have we learned? DOI
Richard C. Thompson, Winnie Courtene‐Jones, Julien Boucher

и другие.

Science, Год журнала: 2024, Номер 386(6720)

Опубликована: Сен. 19, 2024

Twenty years after the first publication that used term microplastic, we review current understanding, refine definitions, and consider future prospects. Microplastics arise from multiple sources, including tires, textiles, cosmetics, paint, fragmentation of larger items. They are widely distributed throughout natural environment, with evidence harm at levels biological organization. pervasive in food drink have been detected human body, emerging negative effects. Environmental contamination could double by 2040, wide-scale has predicted. Public concern is increasing, diverse measures to address microplastic pollution being considered international negotiations. Clear on efficacy potential solutions now needed issue minimize risks unintended consequences.

Язык: Английский

Процитировано

218

A critical review of the adsorption-desorption characteristics of antibiotics on microplastics and their combined toxic effects DOI Creative Commons
Kefu Wang, Changyan Guo, Li Jiang

и другие.

Environmental Technology & Innovation, Год журнала: 2024, Номер 35, С. 103729 - 103729

Опубликована: Июнь 26, 2024

The interaction between microplastics (MPs) and pollutants is crucial for assessing the environmental risk of MPs. It necessary to pay attention adsorption/desorption behavior antibiotics on MPs due their potential role in antibiotic resistance. When MPs-loaded are ingested by organisms, they enter gastrointestinal tract undergo desorption, leading corresponding toxic effects. Existing literature primarily focuses adsorption behavior, while there a lack systematic generalizations desorption or combined effects organisms. Therefore, this article provides review mechanisms, biological tract. Desorption suggests that characteristics (aging hydrophobicity) components fluid (digestive enzyme species pH) can also have effect desorption. Moreover, summarizes induced MPs-antibiotics, demonstrating either enhance reduce plants, microorganisms, aquatic animals. Since methodological uniformity relevance natural environment main shortcomings existing literature, future research should focus actual water given region studying at gene, protein, metabolic levels. This direction expected provide valuable references insights evaluating antibiotics.

Язык: Английский

Процитировано

19

Exploring developmental toxicity of microplastics and nanoplastics (MNPS): Insights from investigations using zebrafish embryos DOI

Wenlong Huang,

Jiezhang Mo, Jiejie Li

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 933, С. 173012 - 173012

Опубликована: Май 6, 2024

Язык: Английский

Процитировано

14

Ingested Polystyrene Micro-Nanoplastics Increase the Absorption of Co-Ingested Arsenic and Boscalid in an In Vitro Triculture Small Intestinal Epithelium Model DOI Creative Commons
Davood Kharaghani, Glen M. DeLoid, Trung Huu Bui

и другие.

Microplastics, Год журнала: 2025, Номер 4(1), С. 4 - 4

Опубликована: Янв. 7, 2025

Micro-nano plastics (MNPs) are emerging environmental and food contaminants that raising serious health concerns. Due to the polycontamination of web with pollutants (EPs), now MNPs, co-ingestion EPs MNPs is likely occur, potential synergistic effects such co-ingestions completely unstudied. In this study, we therefore sought determine two model EPs, arsenic boscalid, on uptake toxicity 25 1000 nm polystyrene (PS-25 PS-1000), vice versa, employing a triculture small intestinal epithelium combined simulated digestion. 24 h exposures, neither nor + caused significant toxicity. The presence PS-25 significantly increased (from 0.0 5.8%, p < 0.001) translocation 5.2 9.8%, 0.05) but had no effect boscalid or translocation, whereas PS-1000 either EP. both PS was also by rising from 10.6 19.5% (p 0.01) for 4.8 8.5% PS-1000. These findings highlight need further studies assess MNP-EP interactions possible adverse impacts.

Язык: Английский

Процитировано

1

Behavioral and Molecular Neurotoxicity of Thermally Degraded Polystyrene in Caenorhabditis elegans DOI
Hui Li, Jinyu Chen, Chenyin Dong

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 487, С. 137212 - 137212

Опубликована: Янв. 13, 2025

Язык: Английский

Процитировано

1

Ecological and Health Risk Mediated by Micro(nano)plastics Aging Process: Perspectives and Challenges DOI
Kyuseok Song, Shu-Hong Gao,

Yu-Sheng Pan

и другие.

Environmental Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Март 19, 2025

Aged micro(nano)plastics (MNPs) are normally the ultimate state of plastics in environment after aging. The changes physical and chemical characteristics aged MNPs significantly influence their environmental behavior by releasing additives, forming byproducts, adsorbing contaminants. However, a systematic review is lacking on effects ecological human health regarding increasing but scattered studies results. This Review first summarizes unique methods for quantifying aging degree. Then we focused potential impacts organisms, ecosystems, health, including "Trojan horse" under real conditions. Through combining meta-analysis analytic hierarchy process (AHP) model, demonstrated that, compared to virgin MNPs, would result biomass decrease oxidative stress increase organisms lead total N/P greenhouse gas emissions ecosystems while causing cell apoptosis, antioxidant system reaction, inflammation health. Within framework risk assessment, used quotient (RQ) physiologically based pharmacokinetic (PBK) models as examples illustrate importance considering degree data acquisition, model building, formula evaluation. Given risks our urgent call more understand hazards real-world environments.

Язык: Английский

Процитировано

1

Seasonal dynamics, tidal influences, and anthropogenic impacts on microplastic distribution in the Yangtze River estuary: A comprehensive characterization and comparative analysis DOI
Panfeng Wu, Yuchuan Fan, Xinxin Zhang

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 476, С. 135167 - 135167

Опубликована: Июль 14, 2024

Язык: Английский

Процитировано

9

Polystyrene nanoplastics induce lipophagy via the AMPK/ULK1 pathway and block lipophagic flux leading to lipid accumulation in hepatocytes DOI

Zhuying Fan,

Yukang Zhang,

Yuting Fang

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 476, С. 134878 - 134878

Опубликована: Июнь 12, 2024

Язык: Английский

Процитировано

8

Microplastic and antibiotics in waters: Interactions and environmental risks DOI
Jiayi Guo, Xuefeng Jin, Yi Zhou

и другие.

Journal of Environmental Management, Год журнала: 2024, Номер 371, С. 123125 - 123125

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

8

Microplastics supply contaminants in food chain: non-negligible threat to health safety DOI

Hongwen Xu,

Zhenyang Hu,

Yingying Sun

и другие.

Environmental Geochemistry and Health, Год журнала: 2024, Номер 46(8)

Опубликована: Июль 3, 2024

Язык: Английский

Процитировано

7